| Name | P glycoprotein |
|---|---|
| Synonyms | ABC20; MDR1; ABCB 1; ABCB1; ATP binding cassette sub family B member 1; CD243; CD243 antigen; CLCS… |
| Name | chloroform |
|---|---|
| CAS | trichloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17560460 | Turgut S, Yaren A, Kursunluoglu R, Turgut G: MDR1 C3435T polymorphism in patients with breast cancer. . Arch Med Res. 2007 Jul;38(5):539-44. Epub 2007 Apr 26. DNA was extracted from peripheral blood samples by standard /chloroform extraction method. |
7(0,0,0,7) | Details |
| 18690658 | Engi H, Hohmann J, Gang G, Pusztai R, Redei D, Kovacs O, Schelz Z, Molnar J: Chemoprevention and inhibition of P-glycoprotein in cancer cells by Chinese medicinal herbs. Phytother Res. 2008 Dec;22(12):1671-6. In the present work, extracts of 12 selected herbs were prepared with chloroform, ethyl and water, and the effects of these on the multidrug resistance (MDR) and P-glycoprotein of mouse lymphoma cells transfected with the human mdr1 gene and on a human lung alveolar epithelial cell line were investigated. |
7(0,0,1,2) | Details |
| 17986257 | Regev R, Katzir H, Yeheskely-Hayon D, Eytan GD: Modulation of P-glycoprotein-mediated multidrug resistance by acceleration of passive drug permeation across the plasma membrane. FEBS J. 2007 Dec;274(23):6204-14. Epub 2007 Nov 6. Whereas Pluronic P85, Tween-20, Triton X-100 and Cremophor EL modulated MDR by inhibition of Pgp-mediated efflux, with no appreciable effect on transbilayer movement of drugs, the anesthetics chloroform, benzyl diethyl ether and propofol modulated MDR by accelerating transbilayer movement of drugs, with no concomitant inhibition of Pgp-mediated efflux. |
2(0,0,0,2) | Details |