| Name | phosphatidylinositol 3 kinase (protein family or complex) |
|---|---|
| Synonyms | PI3 kinase; PI3 kinases; PI3K; Phosphatidylinositol 3 kinase; Phosphatidylinositol 3 kinases; Phosphatidylinositol 4,5 bisphosphate 3 kinase; Phosphatidylinositol 4,5 bisphosphate 3 kinases |
| Name | chloroform |
|---|---|
| CAS | trichloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18577687 | Chen YL, Jian MH, Lin CC, Kang JC, Chen SP, Lin PC, Hung PJ, Chen JR, Chang WL, Lin SZ, Harn HJ: The induction of orphan nuclear receptor Nur77 expression by n-butylenephthalide as pharmaceuticals on hepatocellular carcinoma cell therapy. Mol Pharmacol. 2008 Oct;74(4):1046-58. Epub 2008 Jun 24. N-butylidenephthalide (BP), isolated from the chloroform extract of Angelica sinensis, has been examined for its antitumor effects on glioblastoma multiforme brain tumors; however, little is known about its antitumor effects on hepatocellular carcinoma cells. N-butylidenephthalide-related tumor apoptosis was associated with phosphatidylinositol 3-kinase/protein kinase B (AKT)/glycogen synthase kinase-3beta rather than the mitogen-activated protein kinase or protein kinase C pathway. |
1(0,0,0,1) | Details |
| 19003111 | Teruya K, Yamashita M, Tominaga R, Nagira T, Shim SY, Katakura Y, Tokumaru S, Tokumaru K, Barnes D, Shirahata S: Fermented milk, Kefram-Kefir enhances uptake into insulin-responsive muscle cells. Cytotechnology. 2002 Nov;40(1-3):107-16. -soluble or chloroform/-extracted fractions from Kefram-Kefir were examined to evaluate the uptake ability of L6 myotubes.As a result, the water-soluble fraction augmented the uptake of in L6 myotubes both in the presence and absence of insulin stimulation. Furthermore, this augmentation was inhibited in the presence of phosphatidylinositol 3-kinase (PI 3-kinase) inhibitor wortmannin. |
1(0,0,0,1) | Details |
| 19744549 | Kumar R, Balaji S, Uma TS, Sehgal PK: Fruit extracts of Momordica charantia potentiate uptake and up-regulate Glut-4, PPAR gamma and PI3K. J Ethnopharmacol. 2009 Dec 10;126(3):533-7. Epub 2009 Sep 8. Effects of aqueous and chloroform extracts of Momordica charantia fruit on uptake and up-regulation of transporter (Glut-4), peroxisome proliferator activator receptor gamma (PPAR gamma) and phosphatidylinositol-3 kinase (PI3K), were investigated to show its efficacy as a hypoglycaemic agent. |
31(0,1,1,1) | Details |
| 19272638 | Hayes MP, Douglas W, Ellenson LH: Molecular alterations of EGFR and PIK3CA in uterine serous carcinoma. . Gynecol Oncol. 2009 Jun;113(3):370-3. Epub 2009 Mar 9. This study sought to evaluate primary USC tumors for molecular alterations in epidermal growth factor receptor (EGFR) and the recently characterized oncogene PIK3CA, which encodes the catalytic p110-alpha subunit of phosphatidylinositol 3-kinase (PI3K) and thus activates the AKT-mTOR oncogenic pathway. For mutational analysis, neoplastic tissue was microdissected and DNA was extracted with -chloroform. |
1(0,0,0,1) | Details |