Protein Information

Name AP 1 (protein family or complex)
Synonyms AP 1; AP 1 complex; AP1; Adapter related protein complex 1

Compound Information

Name anthraquinone
CAS 9,10-anthracenedione

Reference List

PubMed Abstract RScore(About this table)
9711216 Goto M, Masegi M, Yamauchi T, Chiba K, Kuboi Y, Harada K, Naruse N: K1115 A, a new anthraquinone derivative that inhibits the binding of activator protein-1 (AP-1) to its recognition sites. J Antibiot. 1998 Jun;51(6):539-44.
33(0,1,1,3) Details
9711217 Naruse N, Goto M, Watanabe Y, Terasawa T, Dobashi K: K1115 A, a new anthraquinone that inhibits the binding of activator protein-1 (AP-1) to its recognition sites. J Antibiot. 1998 Jun;51(6):545-52.
32(0,1,1,2) Details
16959273 Lee J, Jung E, Lee J, Huh S, Hwang CH, Lee HY, Kim EJ, Cheon JM, Hyun CG, Kim YS, Park D: Emodin inhibits TNF alpha-induced MMP-1 expression through suppression of activator protein-1 (AP-1). Life Sci. 2006 Nov 25;79(26):2480-5. Epub 2006 Aug 17.

In this study, we found that emodin, an anthraquinone which has been isolated from the rhizome of Rheum palmatum, significantly inhibited TNF alpha-induced MMP-1 gene expression in a concentration-dependent manner.
3(0,0,0,3) Details
11212108 Ijaz T, Tran P, Ruparelia KC, Teesdale-Spittle PH, Orr S, Patterson LH: Anthraquinone-peptides as inhibitors of AP-1 transcription factor. Bioorg Med Chem Lett. 2001 Feb 12;11(3):351-3.
3(0,0,0,3) Details