Protein Information

Name S mephenytoin 4 hydroxylase
Synonyms (R) limonene 6 monooxygenase; Xenobiotic monooxygenase; Mephenytoin 4 hydroxylase; Microsomal monooxygenase; S mephenytoin 4 hydroxylase; (S) limonene 6 monooxygenase; (S) limonene 7 monooxygenase; CPC 9…

Compound Information

Name diazinon
CAS

Reference List

PubMed Abstract RScore(About this table)
11708902 Kappers WA, Edwards RJ, Murray S, Boobis AR: Diazinon is activated by CYP2C19 in human liver. . Toxicol Appl Pharmacol. 2001 Nov 15;177(1):68-76.

Among eight P450-catalyzed reactions, the putative high-affinity component (50 microM diazinon) correlated with S-mephenytoin 4'-hydroxylase activity (r = 0.686, p < 0.01), suggesting the involvement of CYP2C19.
93(0,3,3,3) Details