| Name | phospholipase A2 |
|---|---|
| Synonyms | 14 3 3 protein zeta/delta; Phospholipase A2; KCIP 1; Protein kinase C inhibitor protein 1; 14 3 3 protein/cytosolic phospholipase A2; 14 3 3 zeta; FAS; Factor activating exoenzyme S… |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8702935 | Sapirstein A, Spech RA, Witzgall R, Bonventre JV: Cytosolic phospholipase A2 (PLA2), but not secretory PLA2, potentiates peroxide cytotoxicity in kidney epithelial cells. J Biol Chem. 1996 Aug 30;271(35):21505-13. Phospholipase A2 (PLA2) and reactive species have been implicated both individually and synergistically in various forms of cellular injury. Exposure to peroxide or but not mercuric chloride, resulted in significantly greater lactate dehydrogenase release in LLC-cPLA2 cells when compared with control cells. |
1(0,0,0,1) | Details |
| 3272823 | Kaever V, Firla U, Resch K: Sulfhydryl reagents as model substances for eicosanoid research. Eicosanoids. 1988;1(1):49-57. Therefore, release from prelabelled cells as well as incorporation into different phospholipid species under the influence of mercuric chloride (HgCl2), ethylmercurithiosalicylate (thimerosal), p-hydroxymercuribenzoic acid (PHMB), 0-(3-hydroxymercuri-3-methoxypropyl) carbamoyl-phenoxyacetic acid (mersalyl), N-ethylmaleimide (NEM), and ethacrynic acid were examined. Additionally, direct effects of those substances on corresponding enzyme activities, i.e. phospholipase A2 (PLA2), acyl-CoA synthetase, and lysophospholipid acyltransferase (LAT), on levels, and on cell viability were estimated. |
1(0,0,0,1) | Details |
| 2839361 | Lachowiez RM, Hammoud NM, Teibel JL, Dix JA: Phospholipase activation, free fatty acids and the permeability of a biological membrane. FEBS Lett. 1988 Jul 4;234(1):195-8. The rate of collapse of a gradient across the apical membrane of rat kidney proximal tubule increases upon treatment with mercuric chloride and mellitin, substances which activate phospholipase A2. |
82(1,1,1,2) | Details |
| 3364578 | Chaudhari A, Kirschenbaum MA: Alterations in rabbit renal microvascular prostanoid synthesis in acute renal failure. Am J Physiol. 1988 May;254(5 Pt 2):F684-8. This study assessed whether changes in two microvascular vasodilator prostanoids would correlate with changes seen in renal hemodynamics in rabbits with nephrotoxic renal injury produced by either uranyl or mercuric chloride. These data suggest that the biosynthesis of and may contribute to the maintenance of renal blood flow in the first few days after acute renal injury and further suggest that a mechanism for this increase may be stimulation of phospholipase A2. |
1(0,0,0,1) | Details |