Protein Information

Name Myosin
Synonyms Myosin

Compound Information

Name 2,4-D
CAS 2-(2,4-dichlorophenoxy)acetic acid

Reference List

PubMed Abstract RScore(About this table)
689920 Dux E, Toth I, Dux L, Joo F: The localization of calcium by X-ray microanalysis in myopathic muscle fibers. Histochemistry. 1978 Jul 12;56(3-4):239-44.

Calcium, because the uptake into sarcoplasmic vesicles was inhibited by 2,4-D, could attach to other binding sites, such as to the troponin-C.A long-lasting binding of calcium might lead to a prolonged activation of the actin-myosin system.
81(1,1,1,1) Details
232748 Muhlrad A, Friedman M: Myosin changes in experimental 2,4-dichlorophenoxyacetate myopathy. . Muscle Nerve. 1978 Nov-Dec;1(6):471-8.

The results indicate that there is a change in the heavy chains of myosin isolated from the gastrocnemius muscle in 2,4-D-induced rat myopathy.
11(0,0,1,6) Details
18022655 Shi F, Takasaki H, Komatsu S: Quantitative analysis of auxin-regulated proteins from basal part of leaf sheaths in rice by two-dimensional difference gel electrophoresis. Phytochemistry. 2008 Feb;69(3):637-46. Epub 2007 Nov 26.

These results indicate that mitochondrial complex I subunit is part of the downstream signal cascade of PCIB, whereas myosin heavy chain, mitochondrial [Mn] SOD and EF-1beta' are involved in the 2,4-D signal cascade but are probably upstream of PCIB.
6(0,0,1,1) Details