Protein Information

Name SRBC
Synonyms CD2; SRBC; CD2 molecule; Erythrocyte receptor; HUMCD2A; LFA 2; LFA 3 receptor; LFA2…

Compound Information

Name chlordane
CAS

Reference List

PubMed Abstract RScore(About this table)
3694709 Johnson KW, Kaminski NE, Munson AE: Direct suppression of cultured spleen cell responses by chlordane and the basis for differential effects on in vivo and in vitro immunocompetence. J Toxicol Environ Health. 1987;22(4):497-515.

The antibody response to sheep erythrocytes (SRBC) was suppressed 90% at 10 microM chlordane.
112(1,2,2,2) Details
3486141 Johnson KW, Holsapple MP, Munson AE: An immunotoxicological evaluation of gamma-chlordane. . Fundam Appl Toxicol. 1986 Feb;6(2):317-26.

Variables evaluated included periodic body weights, terminal organ weights, hematology including leukocyte differentials, antibody response to sheep red blood cells (SRBC), lymphoproliferative responses to the mitogens phytohemagglutinin (PHA), concanavalin A (Con A), and lipopolysaccharide (LPS) and allogeneic cells, and the delayed hypersensitivity response (DHR) to keyhole limpet hemocyanin (KLH).
2(0,0,0,2) Details