| Name | MSRA |
|---|---|
| Synonyms | Cytosolic methionine S sulfoxide reductase (Methionine sulfoxide reductase A3); MSRA; Methionine sulfoxide reductase A1; Methionine sulfoxide reductase A2; PMSR; Peptide Met(O) reductase; Peptide methionine sulfoxide reductase; Protein methionine S oxide reductase… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18424444 | Cabreiro F, Picot CR, Perichon M, Castel J, Friguet B, Petropoulos I: Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage. J Biol Chem. 2008 Jun 13;283(24):16673-81. Epub 2008 Apr 17. We report, for the first time, that overexpression of methionine sulfoxide reductase B2 in mitochondria of acute T-lymphoblastic leukemia MOLT-4 cell line, in which methionine sulfoxide reductase A is missing, markedly protects against peroxide-induced oxidative stress by scavenging reactive species. |
1(0,0,0,1) | Details |
| 19665240 | Wu TM, Hsu YT, Sung MS, Hsu YT, Lee TM: Expression of genes involved in redox homeostasis and antioxidant defense in a marine macroalga Ulva fasciata by excess Aquat Toxicol. 2009 Oct 4;94(4):275-85. Epub 2009 Jul 19. Redox-related genes, methionine sulfoxide reductase A (UfMsrA), thioredoxin (UfTrx), cyclophilin (UfCyp), and ferritin (UfFer) that were up-regulated by excess Cu [Wu, T.M., Lee, T.M., 2008. |
1(0,0,0,1) | Details |
| 20060866 | Misiti F, Clementi ME, Giardina B: Oxidation of 35 reduces toxicity of the amyloid beta-peptide (1-42) in neuroblastoma cells (IMR-32) via enzyme methionine sulfoxide reductase A expression and function. Neurochem Int. 2010 Mar;56(4):597-602. Epub 2010 Jan 11. |
1(0,0,0,1) | Details |
| 18466776 | Oien DB, Osterhaus GL, Latif SA, Pinkston JW, Fulks J, Johnson M, Fowler SC, Moskovitz J: MsrA knockout mouse exhibits abnormal behavior and brain levels. Free Radic Biol Med. 2008 Jul 15;45(2):193-200. Epub 2008 Apr 15. Previously, we have described elevated levels of brain pathologies and an abnormal walking pattern in the methionine sulfoxide reductase A knockout (MsrA (-/-)) mouse. |
1(0,0,0,1) | Details |
| 18651754 | Quinternet M, Tsan P, Neiers F, Beaufils C, Boschi-Muller S, Averlant-Petit MC, Branlant G, Cung MT: Solution structure and dynamics of the reduced and oxidized forms of the N-terminal domain of PilB from Neisseria meningitidis. Biochemistry. 2008 Aug 19;47(33):8577-89. Epub 2008 Jul 24. The central and the C-terminal domains display methionine sulfoxide reductase A and B activities, respectively. |
1(0,0,0,1) | Details |
| 19432210 | Pauk VV, Nasibullin TR, Tuktarova IA, Zueva LP, Mustafina OE: [Antioxidant gene polymorphism and longevity] . Adv Gerontol. 2008;21(4):593-5. On sample of 1534 ethnic Tatars catalase (CAT, -262C/T), glutathione peroxidase 1 (GPX1, L198P) and methionine sulfoxide reductase A (MSRA, -402C/T) gene polymorphisms in connection with lifespan were studied. |
1(0,0,0,1) | Details |
| 18054192 | Cabreiro F, Perichon M, Jatje J, Malavolta M, Mocchegiani E, Friguet B, Petropoulos I: supplementation in the elderly subjects: effect on oxidized protein degradation and repair systems in peripheral blood lymphocytes. Exp Gerontol. 2008 May;43(5):483-7. Epub 2007 Oct 25. The status of the proteasome, which is in charge of oxidized protein degradation and the repair enzymes peptide methionine sulfoxide reductases, which can reverse oxidation in proteins, were analysed on peripheral blood lymphocytes collected from 20 elderly subjects (age range between 59 and 85 years old) before and after zinc supplementation (10mg of zinc per day for 48+/-2 days). |
1(0,0,0,1) | Details |
| 19487311 | Salmon AB, Perez VI, Bokov A, Jernigan A, Kim G, Zhao H, Levine RL, Richardson A: Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span. FASEB J. 2009 Oct;23(10):3601-8. Epub 2009 Jun 1. Methionine sulfoxide reductase A (MsrA) repairs oxidized residues within proteins and may also function as a general antioxidant. |
1(0,0,0,1) | Details |
| 19833874 | Rosen H, Klebanoff SJ, Wang Y, Brot N, Heinecke JW, Fu X: oxidation contributes to bacterial killing by the myeloperoxidase system of neutrophils. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18686-91. Epub 2009 Oct 15. Disruption of bacterial repair systems rendered E. coli more susceptible to killing by HOCl, whereas over-expression of a repair enzyme, methionine sulfoxide reductase A, rendered them resistant, suggesting a direct role for oxidation in bactericidal activity. |
1(0,0,0,1) | Details |
| 18692284 | Schwerin M, Kurts-Ebert B, Beyer M, Swalve H, Junghans P: Temporary consumption of diet with unbalanced amino acid pattern affects long-lasting growth retardation correlated with oxidative stress response associated gene expression in juvenile pigs. Clin Nutr. 2008 Oct;27(5):781-9. Epub 2008 Aug 8. RESULTS: Temporary feeding of SPI diet resulted in prolonged up-regulation of genes involved in oxidative/cellular stress response (glutathione-S-transferase, peptide methionine sulfoxide reductase, calnexin, organic anion transport polypeptide 2). |
1(0,0,0,1) | Details |
| 17624316 | Su Z, Limberis J, Martin RL, Xu R, Kolbe K, Heinemann SH, Hoshi T, Cox BF, Gintant GA: Functional consequences of oxidation of hERG channels. Biochem Pharmacol. 2007 Sep 1;74(5):702-11. Epub 2007 Jun 7. In HEK 293 cells, the effects of ChT on hERG current were time- and concentration-dependent, and were markedly attenuated in the presence of enzyme methionine sulfoxide reductase A that specifically repairs oxidized |
1(0,0,0,1) | Details |
| 17418992 | Picot CR, Moreau M, Juan M, Noblesse E, Nizard C, Petropoulos I, Friguet B: Impairment of reductase during UV irradiation and photoaging. Exp Gerontol. 2007 Sep;42(9):859-63. Epub 2007 Feb 21. Using quantitative confocal microscopy, the amount of methionine sulfoxide reductase A was found significantly lower in sun-exposed skin as compared to sun-protected skin. |
1(0,0,0,1) | Details |
| 18239417 | Park AK, Shin YJ, Moon JH, Kim YK, Hwang KY, Chi YM: Overexpression, purification, and preliminary X-ray crystallographic studies of methionine sulfoxide reductase B from Bacillus subtilis. J Microbiol Biotechnol. 2008 Jan;18(1):59-62. The peptide methionine sulfoxide reductases Msrs) are enzymes that catalyze the reduction of back to |
1(0,0,0,1) | Details |
| 19557161 | Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, Aulchenko YS, Chambers JC, Drong A, Luan J, Lyon HN, Rivadeneira F, Sanna S, Timpson NJ, Zillikens MC, Zhao JH, Almgren P, Bandinelli S, Bennett AJ, Bergman RN, Bonnycastle LL, Bumpstead SJ, Chanock SJ, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Doney AS, Ebrahim S, Elliott P, Erdos MR, Estrada K, Ferrucci L, Fischer G, Forouhi NG, Gieger C, Grallert H, Groves CJ, Grundy S, Guiducci C, Hadley D, Hamsten A, Havulinna AS, Hofman A, Holle R, Holloway JW, Illig T, Isomaa B, Jacobs LC, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Lathrop GM, Lawlor DA, Mangino M, McArdle WL, Meitinger T, Morken MA, Morris AP, Munroe P, Narisu N, Nordstrom A, Nordstrom P, Oostra BA, Palmer CN, Payne F, Peden JF, Prokopenko I, Renstrom F, Ruokonen A, Salomaa V, Sandhu MS, Scott LJ, Scuteri A, Silander K, Song K, Yuan X, Stringham HM, Swift AJ, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Walters GB, Weedon MN, Witteman JC, Zhang C, Zhang W, Caulfield MJ, Collins FS, Davey Smith G, Day IN, Franks PW, Hattersley AT, Hu FB, Jarvelin MR, Kong A, Kooner JS, Laakso M, Lakatta E, Mooser V, Morris AD, Peltonen L, Samani NJ, Spector TD, Strachan DP, Tanaka T, Tuomilehto J, Uitterlinden AG, van Duijn CM, Wareham NJ, Hugh Watkins, Waterworth DM, Boehnke M, Deloukas P, Groop L, Hunter DJ, Thorsteinsdottir U, Schlessinger D, Wichmann HE, Frayling TM, Abecasis GR, Hirschhorn JN, Loos RJ, Stefansson K, Mohlke KL, Barroso I, McCarthy MI: Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet. 2009 Jun;5(6):e1000508. Epub 2009 Jun 26. Follow-up studies in a maximum of 70,689 individuals identified two loci strongly associated with measures of central adiposity; these map near TFAP2B (WC, P = 1.9x10 (-11)) and MSRA (WC, P = 8.9x10 (-9)). |
1(0,0,0,1) | Details |
| 18715149 | Cabreiro F, Picot CR, Perichon M, Friguet B, Petropoulos I: Overexpression of reductases A and B2 protects MOLT-4 cells against zinc-induced oxidative stress. Antioxid Redox Signal. 2009 Feb;11(2):215-25. Among the amino acids, is the most susceptible to oxidation, and can be catalytically reduced within proteins by methionine sulfoxide reductase A (MsrA) and B (MsrB). |
1(0,0,0,1) | Details |
| 17451107 | Junghans P, Beyer M, Derno M, Petzke KJ, Kuchenmeister U, Hennig U, Jentsch W, Schwerin M: Studies on persisting effects of soy-based compared with amino acid-supplemented casein-based diet on protein metabolism and oxidative stress in juvenile pigs. Arch Anim Nutr. 2007 Apr;61(2):75-89. After switching back from SPI to CAS diet the decrease of WBPS of the test group vs. control group was of borderline significance (p = 0.061), transcript levels of hepatic gene expressions of leucine aminopeptidase, endopeptidase 24.16, glutathione-S-transferase and peptide methionine sulfoxide reductase were increased. |
1(0,0,0,1) | Details |
| 17500063 | Gand A, Antoine M, Boschi-Muller S, Branlant G: Characterization of the amino acids involved in substrate specificity of methionine sulfoxide reductase A. J Biol Chem. 2007 Jul 13;282(28):20484-91. Epub 2007 May 11. MsrAs are stereo-specific toward the S epimer on the of the sulfoxide, whereas MsrBs are specific toward the R isomer. |
1(0,0,0,1) | Details |
| 18083115 | Prentice HM, Moench IA, Rickaway ZT, Dougherty CJ, Webster KA, Weissbach H: MsrA protects cardiac myocytes against hypoxia/reoxygenation induced cell death. Biochem Biophys Res Commun. 2008 Feb 15;366(3):775-8. Epub 2007 Dec 18. The enzyme methionine sulfoxide reductase-A (MsrA) is capable of protecting cells against oxidative damage by reversing damage to proteins caused by oxidation or by decreasing ROS through a scavenger mechanism. |
1(0,0,0,1) | Details |
| 19237503 | Wood JM, Decker H, Hartmann H, Chavan B, Rokos H, Spencer JD, Hasse S, Thornton MJ, Shalbaf M, Paus R, Schallreuter KU: Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting repair. FASEB J. 2009 Jul;23(7):2065-75. Epub 2009 Feb 23. Moreover, we demonstrate almost absent catalase and methionine sulfoxide reductase A and B protein expression via immunofluorescence and Western blot in association with a functional loss of (Met-S=O) repair in the entire gray hair follicle. |
1(0,0,0,1) | Details |
| 19461988 | Brennan LA, Lee W, Cowell T, Giblin F, Kantorow M: Deletion of mouse MsrA results in HBO-induced cataract: MsrA repairs mitochondrial cytochrome c. Mol Vis. 2009 May 15;15:985-99. PURPOSE: Considerable evidence indicates a role for methionine sulfoxide reductase A (MsrA) in lens cell resistance to oxidative stress through its maintenance of mitochondrial function. |
1(0,0,0,1) | Details |
| 19733220 | Brennan LA, Lee W, Giblin FJ, David LL, Kantorow M: Methionine sulfoxide reductase A (MsrA) restores alpha-crystallin chaperone activity lost upon oxidation. Biochim Biophys Acta. 2009 Dec;1790(12):1665-72. Epub 2009 Sep 3. Two proteins that cause cataract when deleted from the lens are methionine sulfoxide reductase A (MsrA) that repairs protein methionine sulfoxide (PMSO) oxidized proteins and alpha-crystallin which is a two-subunit (alphaA and alphaB) chaperone. |
32(0,1,1,2) | Details |
| 19844733 | Ogawa F, Shimizu K, Hara T, Muroi E, Komura K, Takenaka M, Hasegawa M, Fujimoto M, Takehara K, Sato S: Autoantibody against one of the antioxidant repair enzymes, methionine sulfoxide reductase A, in systemic sclerosis: association with pulmonary fibrosis and vascular damage. Arch Dermatol Res. 2010 Jan;302(1):27-35. Epub 2009 Oct 21. |
10(0,0,0,10) | Details |
| 19388147 | Oien DB, Canello T, Gabizon R, Gasset M, Lundquist BL, Burns JM, Moskovitz J: Detection of oxidized in selected proteins, cellular extracts and blood serums by novel anti- antibodies. Arch Biochem Biophys. 2009 May 1;485(1):35-40. Furthermore, mouse serum albumin and immunoglobulin (IgG) were shown to accumulate MetO as function of age especially in serums of methionine sulfoxide reductase A knockout mice. |
1(0,0,0,1) | Details |
| 19082015 | Stalford SA, Fascione MA, Sasindran SJ, Chatterjee D, Dhandayuthapani S, Turnbull WB: A natural carbohydrate substrate for Mycobacterium tuberculosis methionine sulfoxide reductase A. Chem Commun. 2009 Jan 7;(1):110-2. Epub 2008 Nov 11. |
1(0,0,0,1) | Details |
| 19558554 | Zhou Z, Li CY, Li K, Wang T, Zhang B, Gao TW: Decreased sulphoxide reductase A expression renders melanocytes more sensitive to oxidative stress: a possible cause for melanocyte loss in vitiligo. Br J Dermatol. 2009 Sep;161(3):504-9. Epub 2009 May 5. OBJECTIVES: To investigate whether the decreased expression of MSRA is one of the reasons why melanocytes are especially vulnerable to oxidative stress in vitiligo. |
9(0,0,0,9) | Details |
| 18506707 | Walss-Bass C, Soto-Bernardini MC, Johnson-Pais T, Leach RJ, Ontiveros A, Nicolini H, Mendoza R, Jerez A, Dassori A, Chavarria-Siles I, Escamilla MA, Raventos H: reductase: a novel schizophrenia candidate gene. Am J Med Genet B Neuropsychiatr Genet. 2009 Mar 5;150B(2):219-25. reductase (MSRA) is an antioxidant enzyme implicated in protection against oxidative stress and protein maintenance. |
8(0,0,0,8) | Details |
| 18255097 | Ranaivoson FM, Antoine M, Kauffmann B, Boschi-Muller S, Aubry A, Branlant G, Favier F: A structural analysis of the catalytic mechanism of methionine sulfoxide reductase A from Neisseria meningitidis. J Mol Biol. 2008 Mar 14;377(1):268-80. Epub 2008 Jan 16. The reductases (Msrs) are thioredoxin-dependent oxidoreductases that catalyse the reduction of the sulfoxide function of the oxidized residues. |
1(0,0,0,1) | Details |
| 18455987 | Erickson JR, Joiner ML, Guan X, Kutschke W, Yang J, Oddis CV, Bartlett RK, Lowe JS, O'Donnell SE, Aykin-Burns N, Zimmerman MC, Zimmerman K, Ham AJ, Weiss RM, Spitz DR, Shea MA, Colbran RJ, Mohler PJ, Anderson ME: A dynamic pathway for -independent activation of CaMKII by oxidation. Cell. 2008 May 2;133(3):462-74. CaMKII oxidation is reversed by methionine sulfoxide reductase A (MsrA), and MsrA-/- mice show exaggerated CaMKII oxidation and myocardial apoptosis, impaired cardiac function, and increased mortality after myocardial infarction. |
1(0,0,0,1) | Details |
| 19542914 | Taungjaruwinai WM, Bhawan J, Keady M, Thiele JJ: Differential expression of the antioxidant repair enzyme reductase (MSRA and MSRB) in human skin. Am J Dermatopathol. 2009 Jul;31(5):427-31. Recently, the antioxidant repair enzymes -S-sulfoxide reductase A (MSRA) and methionine-R-sulfoxide reductase B (MSRB) were described in human epidermal keratinocytes and melanocytes. |
8(0,0,1,3) | Details |
| 17784942 | Lei KF, Wang YF, Zhu XQ, Lu PC, Sun BS, Jia HL, Ren N, Ye QH, Sun HC, Wang L, Tang ZY, Qin LX: Identification of MSRA gene on chromosome 8p as a candidate metastasis suppressor for human hepatitis B virus-positive hepatocellular carcinoma. BMC Cancer. 2007 Sep 4;7:172. |
5(0,0,0,5) | Details |
| 18032652 | Wassef R, Haenold R, Hansel A, Brot N, Heinemann SH, Hoshi T: Methionine sulfoxide reductase A and a dietary supplement prevent Parkinson's-like symptoms. J Neurosci. 2007 Nov 21;27(47):12808-16. |
5(0,0,0,5) | Details |
| 20006300 | Dhandayuthapani S, Jagannath C, Nino C, Saikolappan S, Sasindran SJ: Methionine sulfoxide reductase B (MsrB) of Mycobacterium smegmatis plays a limited role in resisting oxidative stress. Tuberculosis. 2009 Dec;89 Suppl 1:S26-32. We have previously reported, using Mycobacterium smegmatis as a model to identify the bacterial components that resist intracellular ROI, that an antioxidant methionine sulfoxide reductase A (MsrA) plays a critical role in this process. |
1(0,0,0,1) | Details |
| 19085252 | Haenold R, Wassef R, Brot N, Neugebauer S, Leipold E, Heinemann SH, Hoshi T: Protection of vascular smooth muscle cells by over-expressed sulphoxide reductase A: role of intracellular localization and substrate availability. Free Radic Res. 2008 Nov;42(11-12):978-88. sulphoxide reductase A (MSRA) that reduces -S-sulphoxide back to constitutes a catalytic antioxidant mechanism to prevent oxidative damage at multiple sub-cellular loci. |
4(0,0,0,4) | Details |
| 18845237 | Pascual I, Larrayoz IM, Rodriguez IR: regulates the human methionine sulfoxide reductase A (MSRA) gene via two distinct promoters. Genomics. 2009 Jan;93(1):62-71. Epub 2008 Oct 25. |
4(0,0,0,4) | Details |
| 17943184 | Schallreuter KU, Rubsam K, Gibbons NC, Maitland DJ, Chavan B, Zothner C, Rokos H, Wood JM: reductases A and B are deactivated by peroxide (H2O2) in the epidermis of patients with vitiligo. J Invest Dermatol. 2008 Apr;128(4):808-15. Epub 2007 Oct 18. Such high concentrations of H (2) O (2) oxidize residues in proteins and peptides to (R and sulfoxide diasteriomers. In this report, we show that the expression/activities of MSRA and MSRB are significantly decreased in the epidermis of patients with vitiligo compared to healthy controls. |
3(0,0,0,3) | Details |
| 19747232 | Minniti AN, Cataldo R, Trigo C, Vasquez L, Mujica P, Leighton F, Inestrosa NC, Aldunate R: Methionine sulfoxide reductase A expression is regulated by the DAF-16/FOXO pathway in Caenorhabditis elegans. Aging Cell. 2009 Dec;8(6):690-705. Epub 2009 Sep 11. |
3(0,0,0,3) | Details |
| 17624653 | Cabreiro F, Picot CR, Perichon M, Mary J, Friguet B, Petropoulos I: Identification of proteins undergoing expression level modifications in WI-38 SV40 fibroblasts overexpressing methionine sulfoxide reductase A. Biochimie. 2007 Nov;89(11):1388-95. Epub 2007 May 24. |
3(0,0,0,3) | Details |
| 20167203 | Uthus EO: Determination of the specific activities of methionine sulfoxide reductase A and B by capillary electrophoresis. Anal Biochem. 2010 Feb 16. The method is based on detection of the 4-(dimethylamino) azobenzene-4'-sulfonyl derivative of (dabsyl Met), the product of the enzymatic reactions when either dabsyl S-sulfoxide or dabsyl R-sulfoxide is used as a substrate. |
2(0,0,0,2) | Details |
| 19653131 | Oien DB, Shinogle HE, Moore DS, Moskovitz J: Clearance and phosphorylation of alpha-synuclein are inhibited in methionine sulfoxide reductase a null yeast cells. J Mol Neurosci. 2009 Nov;39(3):323-32. Epub 2009 Aug 4. |
2(0,0,0,2) | Details |
| 18456002 | Liu F, Hindupur J, Nguyen JL, Ruf KJ, Zhu J, Schieler JL, Bonham CC, Wood KV, Davisson VJ, Rochet JC: Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults. Free Radic Biol Med. 2008 Aug 1;45(3):242-55. Epub 2008 Apr 11. |
2(0,0,0,2) | Details |
| 19854239 | Oien DB, Osterhaus GL, Lundquist BL, Fowler SC, Moskovitz J: Caloric restriction alleviates abnormal locomotor activity and levels in the brain of the methionine sulfoxide reductase A knockout mouse. Neurosci Lett. 2010 Jan 1;468(1):38-41. Epub 2009 Oct 23. |
2(0,0,0,2) | Details |
| 19415325 | Guo X, Wu Y, Wang Y, Chen Y, Chu C: OsMSRA4.1 and OsMSRB1.1, two rice plastidial reductases, are involved in abiotic stress responses. Planta. 2009 Jun;230(1):227-38. Epub 2009 May 5. In proteins, residues are especially sensitive to oxidation, leading to the formation of S- and R- diastereoisomers, and these two sulfoxides can be specifically reversed by two types of reductases (MSRs), MSRA and MSRB. |
2(0,0,0,2) | Details |
| 18767149 | Kim HY, Zhang Y, Lee BC, Kim JR, Gladyshev VN: The selenoproteome of Clostridium sp. Proteins. 2009 Mar;74(4):1008-17. OhILAs: characterization of anaerobic bacterial selenoprotein methionine sulfoxide reductase A.. |
2(0,0,0,2) | Details |
| 19392687 | Bechtold U, Rabbani N, Mullineaux PM, Thornalley PJ: Quantitative measurement of specific biomarkers for protein oxidation, nitration and glycation in Arabidopsis leaves. Plant J. 2009 Aug;59(4):661-71. Epub 2009 Apr 25. A comparison between wild-type plants and a mutant lacking peptide methionine sulfoxide reductase (pmsr2-1) showed increased protein oxidation, nitration and glycation of specific amino acid residues during darkness in pmsr2-1. |
1(0,0,0,1) | Details |
| 19646993 | Le HT, Chaffotte AF, Demey-Thomas E, Vinh J, Friguet B, Mary J: Impact of peroxide on the activity, structure, and conformational stability of the oxidized protein repair enzyme methionine sulfoxide reductase A. J Mol Biol. 2009 Oct 16;393(1):58-66. Epub 2009 Jul 30. |
1(0,0,0,1) | Details |
| 19343712 | Alvarez S, Berla BM, Sheffield J, Cahoon RE, Jez JM, Hicks LM: Comprehensive analysis of the Brassica juncea root proteome in response to cadmium exposure by complementary proteomic approaches. Proteomics. 2009 May;9(9):2419-31. This study determined the involvement of enzymes such as peptide methionine sulfoxide reductase and 2-nitropropane dioxygenase in alternatives redox-regulation mechanisms, as well as sulfhydrylase, glutathione-S-transferase and -conjugate membrane transporter, as essential players in the Cd hyperaccumation and tolerance of B. juncea. |
1(0,0,0,1) | Details |
| 19686038 | Moskovitz J, Oien DB: Protein carbonyl and the reductase system. Antioxid Redox Signal. 2010 Mar;12(3):405-15. Supportive evidence for this possibility arises from the elevated protein-carbonyl accumulations observed in organisms, such as yeast and mice, lacking the methionine sulfoxide reductase A (MsrA) enzyme. |
1(0,0,0,1) | Details |