Wenjie Li

Emailwjli12345@126.com

Education Background:

2016.09-Present       East China University of Science and Technology, Shanghai, China

Doctorate degree in Medical Science (Major: pharmacy)

  • Awards: second class academic scholarship (2016-2019) &first class academic scholarship (2020-2021)
  • Earned the honorary title of “Outstanding students” (2017-2018)

2012.09-2016.06       Yancheng Institute of Technology, Jiangsu, China

Bachelor’s degree in engineering science (Major: Pharmaceutical engineering)

  • Awards: first class academic scholarship (2012-2016)
  • Obtained the certificates of CET-6 (520 points) and National Certificate in Computing Level 2

Publication:

[1] Le Xu#, Wenjie Li#, Yanyan Diao#, Hongxia Sun, Honglin Li, Lili Zhu*, Hongchang Zhou*, Zhenjiang Zhao*. Synthesis, Design, and Structure-Activity Relationship of the Pyrimidone Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase. Molecules, 2018. 23(6): 1254-1268.

[2] Wanqi Wang#, Yanyan Diao#, Wenjie Li#, Yating Luo, Tingyuan Yang, Yuyu Zhao, Tiantian Qi, Fangling Xu, Xiangyu Ma, Huan Ge, Yingfan Liang, Zhenjiang Zhao, Xin Liang, Rui Wang, Lili Zhu*, Honglin Li*, Yufang Xu*. Design, synthesis and structure-activity relationship study of aminopyridine derivatives as novel inhibitors of Janus Kinase 2. Bioorg. Med. Chem. Lett., 2019. 29(12): 1507-1513.

[3] Dou Dou#, Yanyan Diao#, Wenjie Sha#, Rongrong Su, Linjiang Tong, Wenjie Li, Limin Leng, Lijuan Xie, Zhixiao Yu, Haoming Song, Zihao Shen, Lili Zhu, Zhenjiang Zhao, Hua Xie, Zhuo Chen*, Honglin Li*, Yufang Xu*. Discovery of Pteridine-7(8H)-one Derivatives as Potent and Selective Inhibitors of Bruton’s Tyrosine Kinase (BTK). J. Med. Chem., 2022. 65(3): 2694-2709.

[4] Dou Dou#, Jie Wang#, Yunjin Qiao#, Gulinuer Wumaier#, Wenjie Sha#, Wenjie Li, Wenyi Mei, Tingyuan Yang, Chen Zhang, Huan He, Caolin Wang, Linna Chu, Baihui Sun, Rongrong Su, Xiangyu Ma, Mengdie Gong, Lijuan Xie, Wenzhe Jiang, Yanyan Diao, Lili Zhu, Zhenjiang Zhao, Zhuo Chen*, Yufang Xu*, Shengqing Li*, HonglinLi*. Discovery and optimization of 4-anilinoquinazoline derivatives spanning ATP binding site and allosteric site as effective EGFR-C797S inhibitors. Eur. J. Med. Chem., 2022. 244: 114856.

 

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Honglin Li's Lab
Shanghai Key Laboratory of New Drug Design
School of Pharmacy
East China University of Sci. & Tech.
Room 527, Building 18, 130 Meilong Road,
Shanghai, 200237, P. R. China
Tel: (86) 21 6425 0213
Prof. Honglin Li
hlli@ecust.edu.cn

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