thiodicarb

Identification (Source:EPA,EU)

ID 1363
Name thiodicarb
CAS 59669-26-0
IUPAC
Inchi InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3
CIPAC 543
EPA Code 114501
Formula C10H18N4O4S3
SMILES O=C(ON=C(SC)C)N(SN(C(=O)ON=C(SC)C)C)C
Status Not Approved

Classification

Mode of Action Mainly stomach action but some contact effects. Acetylcholinesterase (AChE) inhibitor.
Pesticide Type Insecticide, Molluscicide, Ovicide
Chemical Group Carbamate
Classification Molluscicides
oxime carbamate insecticides

Properties (Source:PubChem)

Molecular Weight 354.47
Physical State White powder
AlogP 1.729
H-Bond Donor 0
H-Bond Acceptor 9
Surface Area 358.54
Polar Surface Area 159.7

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Chronic 96 hour NOEC, growth 3.2 mg l-1
Algae Acute 72 hour EC50, growth 8.3 mg l-1
Aquatic crustaceans Acute 96 hour LC50 0.014 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.0016 mg l-1
Aquatic invertebrates Acute 48 hour EC50 0.027 mg l-1
Birds Acute LD50 2023 mg kg-1
Birds Short term dietary LC50/LD50 > 5620 mg/kg feed
Earthworms Chronic 14 day NOEC, reproduction 2.0 mg kg-1
Earthworms Acute 14 day LD50 38.5 mg kg-1
Fish Acute 96 hour LC50 1.4 mg l-1
Honeybees Acute 48 hour LD50 0.153 μg bee-1
Mammals Acute oral LD50 50 mg kg-1
Mammals Short term dietary NOEL 10 mg kg-1
Sediment dwelling organisms Chronic 28 day NOEC, sediment 0.08 mg kg-1
Bio-concentration factor BCF 6.3
Bio-concentration factor CT50 12 days

Related targets

Target Name RScore (About this table)
P glycoprotein 250(2,4,7,15) Details
Acetylcholinesterase 172(1,3,5,22) Details
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