Protein Information

Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

Name thiodicarb
CAS

Reference List

PubMed Abstract RScore(About this table)
16461013 Yi MQ, Liu HX, Shi XY, Liang P, Gao XW: Inhibitory effects of four carbamate insecticides on acetylcholinesterase of male and female Carassius auratus in vitro. Comp Biochem Physiol C Toxicol Pharmacol. 2006 May;143(1):113-6. Epub 2006 Feb 3.

The ratios of bimolecular rate constant (female/male) for AChE reacting with methomyl, thiodicarb, carbofuran and carbosulfan were 1.03, 2.44, 1.03 and 1.106, respectively.
122(1,2,3,7) Details
18366586 Hoizey G, Canas F, Binet L, Kaltenbach ML, Jeunehomme G, Bernard MH, Lamiable D: Thiodicarb and methomyl tissue distribution in a fatal multiple compounds poisoning. J Forensic Sci. 2008 Mar;53(2):499-502.

Thiodicarb is a nonsystemic carbamate insecticide whose acetylcholinesterase activity is related to its main methomyl degradation product.
31(0,1,1,1) Details
8980026 Gunning RV, Moores GD, Devonshire AL: Insensitive Acetylcholinesterase and Resistance to Thiodicarb in Australian Helicoverpa armigera Hubner (Lepidoptera: Noctuidae). Pestic Biochem Physiol. 1996 May;55(1):21-8.
7(0,0,1,2) Details
15041023 Li F, Han Z: Mutations in acetylcholinesterase associated with insecticide resistance in the cotton aphid, Aphis gossypii Glover. Insect Biochem Mol Biol. 2004 Apr;34(4):397-405.

6(0,0,0,6) Details
17546082 Chen MH, Han ZJ, Qiao XF, Qu MJ: Mutations in acetylcholinesterase genes of Rhopalosiphum padi resistant to organophosphate and carbamate insecticides. Genome. 2007 Feb;50(2):172-9.

Bioassays showed that the resistant strain used was highly or moderately resistant to pirimicarb, omethoate, and monocrotophos (resistance ratio, 263.8, 53.8, and 17.5, respectively), and showed little resistance to deltamethrin or thiodicarb (resistance ratio, 5.2 and 3.4, respectively).
6(0,0,0,6) Details