acetamiprid

Identification (Source:EPA,EU)

ID 1462
Name acetamiprid
CAS 135410-20-7
IUPAC
Inchi InChI=1S/C10H11ClN4/c1-8(14-7-12)15(2)6-9-3-4-10(11)13-5-9/h3-5H,6H2,1-2H3/b14-8+
CIPAC 649
EPA Code 099050
Formula C10H11ClN4
SMILES Clc1ncc(cc1)CN(\C(=N\C#N)C)C
Status Approved

Classification

Mode of Action Systemic with translaminar activity having both contact and stomach action. Acetylcholine receptor (nAChR) agonist.
Pesticide Type Insecticide
Chemical Group Neonicotinoid
Classification pyridylmethylamine nicotinoid insecticides

Properties (Source:PubChem)

Molecular Weight 222.67
Physical State Colourless crystals
AlogP 1.079
H-Bond Donor 0
H-Bond Acceptor 4
Surface Area 236.9
Polar Surface Area 52.28

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth > 98.3 mg l-1
Aquatic invertebrates Acute 48 hour EC50 49.8 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 5 mg l-1
Aquatic plants Acute 7 day EC50, biomass 1 mg l-1
Birds Acute LD50 98 mg kg-1
Birds Short term dietary LC50/LD50 > 741 mg/kg bw/day
Earthworms Chronic 14 day NOEC, reproduction 1.26 mg kg-1
Earthworms Acute 14 day LD50 9 mg kg-1
Fish Acute 96 hour LC50 > 100 mg l-1
Fish Chronic 21 day NOEC 19.2 mg l-1
Honeybees Acute 48 hour LD50 8.09 μg bee-1
Mammals Acute oral LD50 213 mg kg-1
Mammals Short term dietary NOEL 15 mg kg-1
Sediment dwelling organisms Chronic 28 day NOEC, sediment 0.005 mg kg-1
Bio-concentration factor CT50 Not available days

Related targets

Target Name RScore (About this table)
acetylcholine receptor (protein family or complex) 135(1,2,3,20) Details
Acetylcholinesterase 97(1,1,3,7) Details
cytochrome P450 (protein family or complex) 83(1,1,1,3) Details
GABA receptor (protein family or complex) 33(0,1,1,3) Details
ATPase 19(0,0,3,4) Details
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