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indoxacarb

Identification (Source:EPA,EU)

ID	1582
Name	indoxacarb
CAS	173584-44-6
IUPAC
Inchi	InChI=1S/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,1-2H3/t21-/m0/s1
CIPAC	612
EPA Code	118200
Formula	C22H17ClF3N3O7
SMILES	FC(F)(F)Oc1ccc(cc1)N(C(=O)OC)C(=O)N3/N=C4/c2c(cc(Cl)cc2)C[C@@]4(OC3)C(=O)OC
Status	Approved

Classification

Mode of Action	Contact and stomach action. Voltage-dependent sodium channel blocker.
Pesticide Type	Insecticide
Chemical Group	Oxadiazine
Classification	oxadiazine insecticides

Properties (Source:PubChem)

Molecular Weight	527.83
Physical State	White powder
AlogP	5.826
H-Bond Donor	0
H-Bond Acceptor	8
Surface Area	454.49
Polar Surface Area	106.97

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	0.11 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.042 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.6 mg l-1
Aquatic plants	Acute	7 day	EC50, biomass	0.084 mg l-1
Birds	Short term dietary		LC50/LD50	340 mg/kg bw/day
Birds	Acute		LD50	98 mg kg-1
Earthworms	Chronic	14 day	NOEC, reproduction	7.8 mg kg-1
Earthworms	Acute	14 day	LD50	> 625 mg kg-1
Fish	Acute	96 hour	LC50	0.65 mg l-1
Fish	Chronic	21 day	NOEC	0.15 mg l-1
Honeybees	Acute	48 hour	LD50	0.094 μg bee-1
Mammals	Acute oral		LD50	268 mg kg-1
Mammals	Short term dietary		NOEL	40 ppm diet
	Bio-concentration factor		CT50	Not available days
	Bio-concentration factor		BCF	520

Related targets

Target Name	RScore (About this table)
sodium channel (protein family or complex)	142(1,2,5,17)	Details
acetylcholine receptors (protein family or complex)	8(0,0,1,3)	Details

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