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cyfluthrin

Identification (Source:EPA,EU)

ID	1602
Name	cyfluthrin
CAS	68359-37-5
IUPAC
Inchi	InChI=1S/C22H18Cl2FNO3/c1-22(2)15(11-19(23)24)20(22)21(27)29-18(12-26)13-8-9-16(25)17(10-13)28-14-6-4-3-5-7-14/h3-11,15,18,20H,1-2H3
CIPAC	385
EPA Code	128831
Formula	C22H18Cl2FNO3
SMILES	Cl/C(Cl)=C/C3C(C(=O)OC(C#N)c2ccc(F)c(Oc1ccccc1)c2)C3(C)C
Status	Approved

Classification

Mode of Action	Non-systemic with contact and stomach action and rapid knock-down effect. Sodium channel modulator.
Pesticide Type	Insecticide
Chemical Group	Pyrethroid
Classification	pyrethroid ester insecticides

Properties (Source:PubChem)

Molecular Weight	434.29
Physical State	Yellow paste
AlogP	5.51
H-Bond Donor	0
H-Bond Acceptor	4
Surface Area	399.78
Polar Surface Area	59.32

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	> 10 mg l-1
Aquatic crustaceans	Acute	96 hour	LC50	0.000002 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.00002 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.00016 mg l-1
Birds	Acute		LD50	> 2000 mg kg-1
Birds	Short term dietary		LC50/LD50	> 5000 mg/kg feed
Earthworms	Acute	14 day	LD50	> 1000 mg kg-1
Fish	Chronic	21 day	NOEC	0.00001 mg l-1
Fish	Acute	96 hour	LC50	0.00047 mg l-1
Honeybees	Acute	48 hour	LD50	0.001 μg bee-1
Mammals	Acute oral		LD50	> 16.2 mg kg-1
Mammals	Short term dietary		NOEL	10 mg kg-1
Mammals	Short term dietary		NOEL	50 ppm diet
Sediment dwelling organisms	Acute	96 hour	LC50	0.00011 mg l-1
	Bio-concentration factor		BCF	506
	Bio-concentration factor		CT50	9 days

Related targets

Target Name	RScore (About this table)
sodium channel (protein family or complex)	116(1,2,2,6)	Details
cis 3	87(1,1,1,7)	Details
chloride channel (protein family or complex)	83(1,1,1,3)	Details
interferon gamma	81(1,1,1,1)	Details
ATPase	35(0,1,1,5)	Details
cytochrome P450 (protein family or complex)	34(0,1,1,4)	Details
iceberg	32(0,1,1,2)	Details
glial fibrillary acidic protein	31(0,1,1,1)	Details
extracellular signal regulated kinase 1	31(0,1,1,1)	Details
interleukin 6	31(0,1,1,1)	Details

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