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methamidophos

Identification (Source:EPA,EU)

ID	249
Name	methamidophos
CAS	10265-92-6
IUPAC
Inchi	InChI=1S/C2H8NO2PS/c1-5-6(3,4)7-2/h1-2H3,(H2,3,4)
CIPAC	355
EPA Code	101201
Formula	C2H8NO2PS
SMILES	O=P(OC)(SC)N
Status	Not Approved

Classification

Mode of Action	Systemic with contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
Pesticide Type	Insecticide, Acaricide, Metabolite
Chemical Group	Organophosphate
Classification	phosphoramidothioate insecticides phosphoramidothioate acaricides

Properties (Source:PubChem)

Molecular Weight	141.13
Physical State	Off-white crystalline solid
AlogP	-0.274
H-Bond Donor	1
H-Bond Acceptor	3
Surface Area	143.89
Polar Surface Area	87.43

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	178 mg l-1
Aquatic crustaceans	Acute	96 hour	LC50	1.05 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.27 mg l-1
Birds	Acute		LD50	10 mg kg-1
Earthworms	Acute	14 day	LD50	34 mg kg-1
Fish	Acute	96 hour	LC50	25 mg l-1
Honeybees	Acute	48 hour	LD50	0.22 μg bee-1
Mammals	Acute oral		LD50	30 mg kg-1
Mammals	Short term dietary		NOEL	0.1 mg kg-1
	Bio-concentration factor		BCF	75
	Bio-concentration factor		CT50	Not available days

Related targets

Target Name	RScore (About this table)
Acetylcholinesterase	3862(34,60,86,232)	Details
cholinesterase	1295(11,20,33,80)	Details
neuropathy target esterase	347(2,7,9,27)	Details
ScFv	95(1,1,3,5)	Details
CS3	88(1,1,2,3)	Details
CS2	87(1,1,2,2)	Details
CS1	40(0,1,2,5)	Details
Fatty acid amide hydrolase	39(0,1,1,9)	Details
Beach	37(0,1,2,2)	Details
interleukin 1	36(0,1,1,6)	Details
alpha tubulin	34(0,1,1,4)	Details
beta actin	34(0,1,1,4)	Details
F11	38(0,0,6,8)	Details

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