pymetrozine

Identification (Source:EPA,EU)

ID 331
Name pymetrozine
CAS 123312-89-0
IUPAC
Inchi InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+
CIPAC 593
EPA Code 101103
Formula C10H11N5O
SMILES O=C2N(/N=C/c1cccnc1)C\C(=N/N2)C
Status Approved

Classification

Mode of Action Selective, neural inhibition of feeding behavior that eventually starves insect.
Pesticide Type Insecticide
Chemical Group Pyridine
Classification Antifeedants

Properties (Source:PubChem)

Molecular Weight 217.23
Physical State Colourless to brown coloured crystals
AlogP -0.292
H-Bond Donor 1
H-Bond Acceptor 4
Surface Area 214.34
Polar Surface Area 69.95

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 21.6 mg l-1
Aquatic crustaceans Acute 96 hour LC50 61.7 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.025 mg l-1
Aquatic invertebrates Acute 48 hour EC50 87 mg l-1
Aquatic plants Acute 7 day EC50, biomass 106 mg l-1
Birds Acute LD50 > 2000 mg kg-1
Birds Short term dietary LC50/LD50 > 5200 mg/kg feed
Earthworms Acute 14 day LD50 > 250 mg kg-1
Earthworms Chronic 14 day NOEC, reproduction 1.39 mg kg-1
Fish Acute 96 hour LC50 > 100 mg l-1
Fish Chronic 21 day NOEC > 11.7 mg l-1
Honeybees Acute 48 hour LD50 > 117 μg bee-1
Mammals Acute oral LD50 5820 mg kg-1
Mammals Short term dietary NOEL 3.7 mg kg-1
Sediment dwelling organisms Chronic 28 day NOEC, sediment 0.313 mg kg-1
Bio-concentration factor CT50 Not available days

Related targets

Target Name RScore (About this table)
GABA receptor (protein family or complex) 33(0,1,1,3) Details
iceberg 32(0,1,1,2) Details
acetylcholine receptors (protein family or complex) 31(0,1,1,1) Details
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