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ioxynil

Identification (Source:EPA,EU)

ID	974
Name	ioxynil
CAS	1689-83-4
IUPAC
Inchi	InChI=1S/C7H3I2NO/c8-5-1-4(3-10)2-6(9)7(5)11/h1-2,11H
CIPAC	86
EPA Code	353200
Formula	C7H3I2NO
SMILES	Ic1cc(C#N)cc(I)c1O
Status	Approved

Classification

Mode of Action	Selective, systemic with contact action, acts by inhibiting photosynthesis at Photosystem II
Pesticide Type	Herbicide, Metabolite
Chemical Group	Hydroxybenzonitrile
Classification	nitrile herbicides

Properties (Source:PubChem)

Molecular Weight	370.91
Physical State	White crystalline solid
AlogP	2.623
H-Bond Donor	1
H-Bond Acceptor	2
Surface Area	208.78
Polar Surface Area	44.02

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	24 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	3.9 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.013 mg l-1
Aquatic plants	Acute	7 day	EC50, biomass	0.027 mg l-1
Birds	Short term dietary		LC50/LD50	1346 mg/kg feed
Birds	Acute		LD50	62 mg kg-1
Earthworms	Acute	14 day	LD50	> 60 mg kg-1
Earthworms	Chronic	14 day	NOEC, reproduction	20.0 mg kg-1
Fish	Acute	96 hour	LC50	8.5 mg l-1
Fish	Chronic	21 day	NOEC	3.2 mg l-1
Honeybees	Acute	48 hour	LD50	10.1 μg bee-1
Mammals	Acute oral		LD50	130 mg kg-1
Mammals	Short term dietary		NOEL	20 ppm diet
Mammals	Short term dietary		NOEL	1 mg kg-1
Sediment dwelling organisms	Chronic	28 day	NOEC, sediment	0.013 mg kg-1
	Bio-concentration factor		CT50	Not available days
	Bio-concentration factor		BCF	29

Related targets

Target Name	RScore (About this table)
transthyretins	369(4,5,6,14)	Details
nitrilase (protein family or complex)	114(1,2,2,4)	Details
protein is	91(1,1,2,6)	Details
mitochondrial ATPase	81(1,1,1,1)	Details
thyroid hormone receptor alpha	81(1,1,1,1)	Details

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