| Name | calcium channel (protein family or complex) |
|---|---|
| Synonyms | calcium channel |
| Name | dichlorvos |
|---|---|
| CAS | 2,2-dichloroethenyl dimethyl phosphate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16635102 | Choudhary S, Verma SK, Raheja G, Kaur P, Joshi K, Gill KD: The L-type calcium channel blocker nimodipine mitigates cytoskeletal proteins phosphorylation in dichlorvos-induced delayed neurotoxicity in rats. Basic Clin Pharmacol Toxicol. 2006 May;98(5):447-55. |
62(0,2,2,2) | Details |
| 11705460 | Choudhary S, Gill KD: Protective effect of nimodipine on dichlorvos-induced delayed neurotoxicity in rat brain (1). Biochem Pharmacol. 2001 Nov 1;62(9):1265-72. This indicates that nimodipine, a centrally acting calcium channel blocker, may contribute to the amelioration of dichlorvos-induced neurotoxicity by attenuation of -mediated disruption of cytoskeletal homeostasis, without preventing NTE inhibition. |
31(0,1,1,1) | Details |
| 19631781 | Liu CY, Chang PA, Wu YJ: Trichlorfon induces apoptosis in SH-SY5Y neuroblastoma cells via the endoplasmic reticulum?. Chem Biol Interact. 2009 Sep 14;181(1):37-44. Epub 2009 Mar 20. Flow cytometric analysis demonstrated that trichlorfon and its degradation product dichlorvos-induced apoptosis in a dose-dependent manner and Hoechst 33342 staining experiments revealed trichlorfon/dichlorvos-induced nucleus condensation. Intracellular Ca (2+) level ([Ca (2+)](i)) in SH-SY5Y cells increased after treatment with trichlorfon but was significantly reduced by pre-treatment with a combination of a calcium channel blocker, an inositol trisphosphate receptor inhibitor, and a ryanodine receptor inhibitor. |
1(0,0,0,1) | Details |
| 12186780 | Choudhary S, Raheja G, Gupta V, Gill KD: Possible involvement of dopaminergic neurotransmitter system in dichlorvos induced delayed neurotoxicity. J Biochem Mol Biol Biophys. 2002 Feb;6(1):29-36. Administration of nimodipine, a centrally acting calcium channel blocker, along with dichlorvos restricted all these alterations to within control values and could also ameliorate certain behavioural deficits by maintaining the dopaminergic neurotransmitter system. |
6(0,0,1,1) | Details |