---

dichlorvos

Identification (Source:EPA,EU)

ID	186
Name	dichlorvos
CAS	62-73-7
IUPAC	2,2-dichlorovinyl dimethyl phosphate
Inchi	InChI=1S/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3
CIPAC	11
EPA Code	084001
Formula	C4H7Cl2O4P
SMILES	O=P(O\C=C(/Cl)Cl)(OC)OC
Status	Not Approved

Classification

Mode of Action	Respiratory, contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
Pesticide Type	Insecticide, Acaricide, Metabolite
Chemical Group	Organophosphate
Classification	organophosphate insecticides organophosphate acaricides

Properties (Source:PubChem)

Molecular Weight	220.98
Physical State	Pale yellow clear liquid
AlogP	0.473
H-Bond Donor	0
H-Bond Acceptor	4
Surface Area	196.89
Polar Surface Area	54.57

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	52.8 mg l-1
Algae	Chronic	96 hour	NOEC, growth	4.73 mg l-1
Aquatic crustaceans	Acute	96 hour	LC50	0.019 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.00019 mg l-1
Birds	Short term dietary		LC50/LD50	251 ppm
Birds	Acute		LD50	24 mg kg-1
Fish	Acute	96 hour	LC50	0.55 mg l-1
Fish	Chronic	21 day	NOEC	0.11 mg l-1
Honeybees	Acute	48 hour	LD50	0.29 μg bee-1
Mammals	Acute oral		LD50	80 mg kg-1
Mammals	Short term dietary		NOEL	0.5 mg kg-1
	Bio-concentration factor		CT50	Not available days

Related targets

Target Name	RScore (About this table)
Acetylcholinesterase	3598(30,53,87,338)	Details
cholinesterase	3402(29,49,83,312)	Details
acylpeptide hydrolase	480(5,7,7,20)	Details
NMDA receptor (protein family or complex)	314(2,6,9,19)	Details
neuropathy target esterase	279(2,5,6,24)	Details
glutathione S transferase	236(2,4,5,11)	Details
albumin	213(2,3,3,23)	Details
Hsp70	166(2,2,2,6)	Details
CREB	113(1,2,2,3)	Details
caspase 3	98(1,1,3,8)	Details
acid phosphatase	96(1,1,2,11)	Details
alkaline phosphatase	96(1,1,3,6)	Details
MAO A	88(1,1,2,3)	Details
microtubule associated protein	87(1,1,2,2)	Details
alanine aminotransferase	87(1,1,2,2)	Details
monoamine oxidase	86(1,1,1,6)	Details
glutaminase	82(1,1,1,2)	Details
adenylyl cyclase	82(1,1,1,2)	Details
CS2	82(1,1,1,2)	Details
adenylate cyclase	81(1,1,1,1)	Details
ATPase	81(1,1,1,1)	Details
interleukin 6	81(1,1,1,1)	Details
calcium channel (protein family or complex)	100(0,3,4,5)	Details
catalase	81(0,2,4,11)	Details
superoxide dismutase	79(0,2,4,9)	Details
lactate dehydrogenase (protein family or complex)	75(0,2,4,5)	Details
Rho kinase	65(0,2,2,5)	Details
glucokinase	46(0,1,3,6)	Details
lymphokine	43(0,1,1,13)	Details
perforin	42(0,1,1,12)	Details
gamma glutamyl transferase	38(0,1,2,3)	Details
glutathione reductase	38(0,1,2,3)	Details
granzyme A	36(0,1,1,6)	Details
CB1 receptor	35(0,1,1,5)	Details
cytochrome P450 (protein family or complex)	35(0,1,1,5)	Details
calmodulin	33(0,1,1,3)	Details
cholesterol esterase	33(0,1,1,3)	Details
histidine decarboxylase	33(0,1,1,3)	Details
MCP	32(0,1,1,2)	Details
S100beta	32(0,1,1,2)	Details
cytochrome c	31(0,1,1,1)	Details
FAME	31(0,1,1,1)	Details
TEPP	31(0,1,1,1)	Details
F11	23(0,0,3,8)	Details

Docunmentation of Network Visuallization