Protein Information

Name calmodulin
Synonyms CALM; CAM; CALM 1; CALM 2; CALM 3; CALM1; CALM2; CALM3…

Compound Information

Name dichlorvos
CAS 2,2-dichloroethenyl dimethyl phosphate

Reference List

PubMed Abstract RScore(About this table)
2993719 Iwaki T, Noguchi A, Sekimoto T: Sources of extramitochondrial corticoidogenic cholesterol in the adrenal cortex. Jpn J Pharmacol. 1985 Jun;38(2):207-14.

The inhibitors were ML-236B (3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor), W-7 (N-(6-aminohexyl)-5-chloro-1-naphthalene sulfonamide; calmodulin inhibitor), dichlorvos (O,O-dimethyl-2,2-dichlorovinyl phosphate; organic phosphorylation inhibitor), chloroquine [7-chloro-4-4-diethylamino-1-methyl-butylamino) quinoline; lysosomal enzyme inhibitor) and cycloheximide (protein synthesis inhibitor).
31(0,1,1,1) Details
16635102 Choudhary S, Verma SK, Raheja G, Kaur P, Joshi K, Gill KD: The L-type calcium channel blocker nimodipine mitigates cytoskeletal proteins phosphorylation in dichlorvos-induced delayed neurotoxicity in rats. Basic Clin Pharmacol Toxicol. 2006 May;98(5):447-55.

Ca2+/Calmodulin-dependent and cAMP dependent protein kinases, at all post exposure intervals (day 7, 15 and 21) as compared to that of controls.
1(0,0,0,1) Details
11282359 Choudhary S, Joshi K, Gill KD: Possible role of enhanced microtubule phosphorylation in dichlorvos induced delayed neurotoxicity in rat. Brain Res. 2001 Apr 6;897(1-2):60-70.

Microtubule associated Ca2+/calmodulin dependent as well as cAMP dependent protein kinases were assayed.
1(0,0,0,1) Details