Protein Information

Name Hsp70
Synonyms APG 2; APG2; HS24/P52; HSP70RY; HSPA 4; HSPA4; Heat shock 70 kDa protein 4; Heat shock 70 related protein APG 2…

Compound Information

Name dichlorvos
CAS 2,2-dichloroethenyl dimethyl phosphate

Reference List

PubMed Abstract RScore(About this table)
17640809 Gupta SC, Siddique HR, Mathur N, Vishwakarma AL, Mishra RK, Saxena DK, Chowdhuri DK: Induction of hsp70, alterations in oxidative stress markers and apoptosis against dichlorvos exposure in transgenic Drosophila melanogaster: modulation by reactive oxygen species. Biochim Biophys Acta. 2007 Sep;1770(9):1382-94. Epub 2007 Jun 16.

We examined a hypothesis that reactive oxygen species (ROS) generated by organophosphate compound dichlorvos modulates Hsp70 expression and anti-oxidant defense enzymes and acts as a signaling molecule for apoptosis in the exposed organism.
166(2,2,2,6) Details
17618723 Gupta SC, Siddique HR, Mathur N, Mishra RK, Mitra K, Saxena DK, Chowdhuri DK: Adverse effect of organophosphate compounds, dichlorvos and chlorpyrifos in the reproductive tissues of transgenic Drosophila melanogaster: 70kDa heat shock protein as a marker of cellular damage. Toxicology. 2007 Aug 16;238(1):1-14. Epub 2007 May 24.

0(0,0,0,0) Details