| 3027258 |
Lummis SC, Chow SC, Holan G, Johnston GA: gamma-Aminobutyric acid receptor ionophore complexes: differential effects of deltamethrin, dichlorodiphenyltrichloroethane, and some novel insecticides in a rat brain membrane preparation. J Neurochem. 1987 Mar;48(3):689-94.
The binding of [35S] t-butylbicyclophosphorothionate ([35S] TBPS), a gamma-aminobutyric acid (GABA)-activated chloride ionophore ligand; [3H] diazepam, a benzodiazepine agonist; and [3H] muscimol, a GABA receptor probe, were used to assess the effects at 100 microM of deltamethrin, dichlorodiphenyltrichloroethane (DDT), and three experimental insecticides--a DDT-pyrethroid hybrid, GH414 (cycloprothrin), and two DDT-analogues, GH266 and GH149 (EDO), on GABA receptor ionophore complexes in a rat brain membrane preparation. |
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