| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | cypermethrin |
|---|---|
| CAS | cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17385498 | Rattanapan A, Visetson S, Ngernsiri L, Milne J: Efficiency of Thai derris extract and cypermethrin: toxicity and detoxification enzyme mechanism in the tropical armyworm, Spodoptera litura F. Commun Agric Appl Biol Sci. 2006;71(2 Pt B):329-37. The cypermethrin was elevated esterase and acetylcholinesterase enzyme activities more than derris extract ca. 0.23 fold and 0.05 fold, respectively. |
6(0,0,1,1) | Details |
| 10355540 | Kale M, Rathore N, John S, Bhatnagar D: Lipid peroxidative damage on pyrethroid exposure and alterations in antioxidant status in rat erythrocytes: a possible involvement of reactive species. Toxicol Lett. 1999 Apr 12;105(3):197-205. A single dose of cypermethrin and/or fenvalerate (0.001% LD50) was administered orally to rats and the animals were sacrificed at 0, 1, 3, 7 and 14 days of treatment. Erythrocytes and serum acetylcholinesterase (AChE) activity was measured in pyrethroid-induced oxidative stress as it may mimic inhibition in target tissues such as muscle and brain. |
3(0,0,0,3) | Details |
| 18755020 | Perera MD, Hemingway J, Karunaratne SP: Multiple insecticide resistance mechanisms involving metabolic changes and insensitive target sites selected in anopheline vectors of malaria in Sri Lanka. Malar J. 2008 Aug 28;7:168. METHODS: Adult females were exposed to the WHO discriminating dosages of DDT, malathion, fenitrothion, propoxur, lambda-cyhalothrin, cyfluthrin, cypermethrin, deltamethrin, permethrin and etofenprox. The presence of metabolic resistance by esterase, glutathione S-transferase (GST) and monooxygenase-based mechanisms, and the sensitivity of the acetylcholinesterase target site were assessed using synergists, and biochemical, and metabolic techniques. |
2(0,0,0,2) | Details |
| 18922205 | Singh V, Singh DK: The effect of abiotic factors on the toxicity of cypermethrin against the snail Lymnaea acuminata in the control of fascioliasis. J Helminthol. 2009 Mar;83(1):39-45. Epub 2008 Oct 16. A significant positive rank correlation between AChE, ACP and ALP activity did exist following exposure to the corresponding sublethal concentrations. |
2(0,0,0,2) | Details |
| 8481527 | Rodriguez M, Ortiz E, Bisset JA, Hemingway J, Saledo E: Changes in malathion and pyrethroid resistance after cypermethrin selection of Culex quinquefasciatus field populations of Cuba. Med Vet Entomol. 1993 Apr;7(2):117-21. Use of the organophosphorus insecticide malathion for mosquito control in Cuba, for 7 years up to 1986, selected elevated non-specific esterase and altered acetylcholinesterase (AChE) resistance mechanisms in Culex quinquefasciatus. |
2(0,0,0,2) | Details |
| 15171950 | Srinivas R, Udikeri SS, Jayalakshmi SK, Sreeramulu K: Identification of factors responsible for insecticide resistance in Helicoverpa armigera. Comp Biochem Physiol C Toxicol Pharmacol. 2004 Mar;137(3):261-9. Moth larvae (Helicoverpa armigera Hubner) collected from field crops were tested for resistance to cypermethrin, fenvalerate, endosulfan, monocrotophos and quinolphos. Acetylcholinesterase of resistant larvae was less sensitive to monocrotophos and methyl paraoxon. |
2(0,0,0,2) | Details |
| 15476966 | Foil LD, Coleman P, Eisler M, Fragoso-Sanchez H, Garcia-Vazquez Z, Guerrero FD, Jonsson NN, Langstaff IG, Li AY, Machila N, Miller RJ, Morton J, Pruett JH, Torr S: Factors that influence the prevalence of acaricide resistance and tick-borne diseases. Vet Parasitol. 2004 Oct 28;125(1-2):163-81. Farmers continued to use amitraz as the major acaricide for tick control after the diagnosis of resistance, although it was supplemented with moxidectin (dairy farms) or fluazuron, macrocyclic lactones or cypermethrin/chlorfenvinphos. Acetylcholine esterase affinity for OPs is changed in resistant tick populations. |
2(0,0,0,2) | Details |
| 19908228 | Carletto J, Martin T, Vanlerberghe-Masutti F, Brevault T: Insecticide resistance traits differ among and within host races in Aphis gossypii. Pest Manag Sci. 2010 Mar;66(3):301-7. Conversely, all clones were resistant to dimethoate (organophosphate) (RF = 4.1-38.1) and carried mutation S431F in the acetylcholinesterase gene. Auber and Burk were highly resistant (RF = 41.2 and 473 respectively) to cypermethrin (pyrethroid). |
1(0,0,0,1) | Details |
| 9805056 | Gonzalez T, Bisset JA, Diaz C, Rodriguez MM, Dieguez L: [The evolution of resistance in a Culex quinquefasciatus strain starting from selection with the pyrethroid insecticide lambdacyhalothrin]. Rev Cubana Med Trop. 1996;48(3):218-23. There was an increase of the levels of resistance to methyl-pyrimifos (2.4 times), propoxur (6 times), DDT (5.2 times), clorpirifos (22 time), cypermethrin (67.5 times), and deltamethrin (20.2 times). The frequencies of the genes that codify for the elevated esterases enzymes and for the modified acetylcholinesterase reached their maximum value. |
1(0,0,0,1) | Details |
| 1292170 | Dudrikova E, Lenhardt L, Poracova J: [Biochemical aspects of the toxic effects of Supermethrin and the histochemical activity of alkaline phosphatase, acid phosphatase and non-specific esterase in subchronic poisoning in sheep]. Vet Med. 1992 Nov;37(11):613-22. During the experiment changes of aspartate aminotransferase (EC 2.6.1.1), alanine aminotransferase (EC 2.6.1.2), acetylcholine esterase (EC 3.1.1.7), urea und levels in blood serum were observed. |
1(0,0,0,1) | Details |
| 11681666 | Maklakov A, Ishaaya I, Freidberg A, Yawetz A, Horowitz AR, Yarom I: Toxicological studies of organophosphate and pyrethroid insecticides for controlling the fruit fly Dacus ciliatus (Diptera: Tephritidae). J Econ Entomol. 2001 Oct;94(5):1059-66. This was supported by the insignificant decrease of head acetylcholinesterase activity. |
1(0,0,0,1) | Details |
| 11826520 | Bisset JA, Rodriguez MM, Diaz C, Soca A: [Course of insecticide resistance in Culex quinquefasciatus (Diptera: Culicidae) in a region of La Habana]. Rev Cubana Med Trop. 2000 Sep-Dec;52(3):180-5. The use of malathion to control mosquitoes in Cuba during 7 years until 1986 selected 2 resistance mechanisms: that of elevated activity of nonspecific esterases and that of altered acetylcholinesterase (Ache) in Culex quinquefasciatus (Say). In Havana, specifically in the area under study (Quibu River), malathion was replaced by cypermethrin in 1987 and cycles of treatment with cypermethrin have been intensively used since 1987 up to now when the populations of Aedes or Culex increase. |
1(0,0,0,1) | Details |
| 19115232 | Roditakis E, Grispou M, Morou E, Kristoffersen JB, Roditakis N, Nauen R, Vontas J, Tsagkarakou A: Current status of insecticide resistance in Q biotype Bemisia tabaci populations from Crete. Pest Manag Sci. 2009 Mar;65(3):313-22. A propoxur-based AChE diagnostic test indicated that iAChE was widespread in most populations. High resistance levels were identified in the majority of populations (> 80%) for imidacloprid (RF: 38-1958x) and alpha-cypermethrin (RF: 30-600x). |
1(0,0,0,1) | Details |
| 19297972 | Gurusubramanian G, Rahman A, Sarmah M, Ray S, Bora S: Pesticide usage pattern in tea ecosystem, their retrospects and alternative measures. J Environ Biol. 2008 Nov;29(6):813-26. Due to this practice, the tea pests showed a higher tolerance/ resistance status due to formation of greater amount of esterases, glutathione S-transferase and acetylcholinesterase. Thus, over reliance on pesticides end up with pesticide residue in made tea (DDT - 10.4-47.1%; endosulfan - 41.1-98.0%; dicofol- 0.0-82.4%; ethion - 0.0-36.2%; cypermethrin - 6.0- 45.1%). |
1(0,0,0,1) | Details |
| 9685989 | Rodriguez MM, Bisset J, Rodriguez I, Diaz C: [Determination of insecticide resistance and its biochemical mechanisms in 2 strains of Culex quinquefasciatus from Santiago de Cuba]. Rev Cubana Med Trop. 1997;49(3):209-14. It was analyzed the behavior of the resistance of 3 organophosphated insecticides (malathion, clorpirifos and methyl-pyrimifos), 3 pyrethroids (deltamethrin, lambda-cyhalothrin and cypermethrin), and 1 (propuxur) in populations of Culex quinquefasciatus from 2 municipalities of the province of Santiago de Cuba. It was determined by the biochemical tests that there existed a high frequency of the mechanisms of esterases and altered acetylcholinesterase. |
1(0,0,0,1) | Details |
| 10774652 | Karunaratne SH: Insecticide cross-resistance spectra and underlying resistance mechanisms of Sri Lankan anopheline vectors of malaria. Southeast Asian J Trop Med Public Health. 1999 Sep;30(3):460-9. Adult mosquitos were individually tested for their insecticide detoxifying enzyme activities and altered target-site, acetylcholinesterase. Adults were also tested for WHO standard discriminating dosages of malathion, propoxur, permethrin, DDT, cypermethrin, deltamethlin and lambda cyhalothrin. |
1(0,0,0,1) | Details |
| 16506569 | Rodriguez MM, Bisset JA, De Armas Y, Ramos F: Pyrethroid insecticide-resistant strain of Aedes aegypti from Cuba induced by deltamethrin selection. J Am Mosq Control Assoc. 2005 Dec;21(4):437-45. After selection for 12 generations with deltamethrin, the Santiago de Cuba colony (SAN-F12) showed little or no cross-resistance to the organophosphates evaluated, but high cross-resistance was observed for all the pyrethroids in larvae from this strain: lambdacyhalothrin (197.5 x), cypermethrin (45 x), and cyfluthrin (41.2 x). |
0(0,0,0,0) | Details |
| 17239417 | Flaskos J, Harris W, Sachana M, Munoz D, Tack J, Hargreaves AJ: The effects of diazinon and cypermethrin on the differentiation of neuronal and glial cell lines. Toxicol Appl Pharmacol. 2007 Mar;219(2-3):172-80. Epub 2006 Dec 15. |
0(0,0,0,0) | Details |
| 11107890 | Diaz C, Perez M, Rodriguez MM, Calvo E, Bisset JA, Fresneda M: [Resistance to insecticides in Blattella germanica species strains from Santiago de Cuba]. Rev Cubana Med Trop. 2000 Jan-Apr;52(1):24-30. A study was conducted on the level of resistance to seven insecticides, namely, 3 organophosphate compounds (malathion, chlorpyrifos and pirimiphos-methyl), one (propoxur) and 1 pyrethroid (cypermethrin, deltamethrin and lambdacialotrine) of three field-collected strains of Blattella germanica (Linnaeus, 1767) from Santiago de Cuba. |
0(0,0,0,0) | Details |
| 10867365 | Gupta A, Agarwal AK, Shukla1 GS: Effect of quinalphos and cypermethrin exposure on developing blood-brain barrier: role of Environ Toxicol Pharmacol. 2000 Jan 1;8(2):73-78. |
0(0,0,0,0) | Details |
| 12716053 | el-Demerdash FM, Yousef MI, Al-Salhen KS: Protective effects of isoflavone on some biochemical parameters affected by cypermethrin in male rabbits. J Environ Sci Health B. 2003 May;38(3):365-78. |
0(0,0,0,0) | Details |
| 11748873 | Latuszynska J, Luty S, Raszewski G, Tokarska-Rodak M, Przebirowska D, Przylepa E, Haratym-Maj A: effect of dermally-applied chlorpyrifos and cypermethrin in Wistar rats. Ann Agric Environ Med. 2001;8(2):163-70. The aim of the study was to evaluate the effect of a dermally-applied mixture of chlorpyrifos and cypermethrin in rats based on cognitive function, activity of the blood cholinesterase and brain acetylcholinesterase, as well as histologic brain examination. |
163(2,2,2,3) | Details |
| 2365420 | Ansari MZ, Kumar A, Prasad RL, Basu A, Sahai BN, Sinha AP: Clinico-biochemical use of serum acetylcholine esterase following treatment with synthetic pyrethroids, cypermethrin and fenvalerate, in cattle and buffalo experimentally infested with Boophilus microplus. Indian J Exp Biol. 1990 Mar;28(3):241-4. Following treatment, cypermethrin and fenvalerate, were found to have inhibitory effect on serum acetylcholine esterase (AchE) activity of cattle and buffalo experimentally infested with B. microplus. |
87(1,1,2,2) | Details |
| 9374595 | McCutchen BF, Hoover K, Preisler HK, Betana MD, Herrmann R, Robertson JL, Hammock BD: Interactions of recombinant and wild-type baculoviruses with classical insecticides and pyrethroid-resistant tobacco budworm (Lepidoptera: Noctuidae). J Econ Entomol. 1997 Oct;90(5):1170-80. A type II pyrethroid (cypermethrin, which modifies currents of channels) and a (methomyl, an inhibitor of acetylcholinesterase) were synergistic in combination with AcAaIT. |
81(1,1,1,1) | Details |
| 1883402 | Reddy AT, Ayyanna K, Yellamma K: Sensitivity of brain cholinesterase to cypermethrin toxicity in freshwater teleost Tilapia mossambica. Biochem Int. 1991 Mar;23(5):959-62. Maximum inhibition of AChE activity is noticed at 6h and 12h after exposure to cypermethrin in juvenile and adult fish respectively. |
38(0,1,2,3) | Details |
| 7595515 | Rao GV, Rao KS: Modulation in acetylcholinesterase of rat brain by pyrethroids in vivo and an in vitro kinetic study. J Neurochem. 1995 Nov;65(5):2259-66. The modulation of acetylcholinesterase (AChE) of rat brain by two pyrethroids--permethrin (PM) and cypermethrin (CPM)--was studied both in vivo and in vitro. |
33(0,1,1,3) | Details |
| 8167458 | Reddy PM, Philip GH: In vivo inhibition of AChE and ATPase activities in the tissues of freshwater fish, Cyprinus carpio exposed to technical grade cypermethrin. Bull Environ Contam Toxicol. 1994 Apr;52(4):619-26. |
31(0,1,1,1) | Details |
| 19830865 | Li SG: [Differences of acetylcholinesterase level in variety classes and strains of Culex pipiens pallens]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2009 Sep;38(5):511-4. The AChE activity of anti-DDVP (Rd) and anti-propoxur (Rp) strains of Culex pipiens pallens was significantly higher than that of sensitive (S) strain (P <0.01), while the AChE activity of anti-cypermethrin (Rc) strain of Culex pipiens pallens was similar to that of S strain (P> 0.05). |
13(0,0,1,8) | Details |
| 10571459 | Bendahou N, Bounias M, Fleche C: Toxicity of cypermethrin and fenitrothion on the hemolymph carbohydrates, head acetylcholinesterase, and thoracic muscle Na+, K+-ATPase of emerging honeybees (Apis mellifera mellifera. Ecotoxicol Environ Saf. 1999 Oct;44(2):139-46. |
7(0,0,1,2) | Details |
| 8385837 | Malaviya M, Husain R, Seth PK, Husain R: Perinatal effects of two pyrethroid insecticides on brain neurotransmitter function in the neonatal rat. Vet Hum Toxicol. 1993 Apr;35(2):119-22. Significant decreases were observed during lactation in monoamine oxidase and acetylcholinesterase in fenvalerate-exposed pups and in acetylcholinesterase and Na+, K (+)-ATPase in cypermethrin-exposed pups. |
7(0,0,1,2) | Details |