| Name | androgen receptor |
|---|---|
| Synonyms | AIS; AR; Androgen receptor; DHTR; Dihydrotestosterone receptor; HUMARA; KD; NR3C4… |
| Name | cypermethrin |
|---|---|
| CAS | cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16857237 | Sun H, Xu XL, Xu LC, Song L, Hong X, Chen JF, Cui LB, Wang XR: Antiandrogenic activity of pyrethroid pesticides and their metabolite in reporter gene assay. Chemosphere. 2007 Jan;66(3):474-9. Epub 2006 Jul 20. We tested three frequently encountered pyrethroids (fenvalerate, cypermethrin, permethrin) and their metabolite 3-phenoxybenzoic acid (3-PBA) for antiandrogenic and androgenic activity using a human androgen receptor (AR) mediated luciferase reporter gene assay in CV-1 African green monkey kidney cell. |
81(1,1,1,1) | Details |
| 17980950 | Xu LC, Liu L, Ren XM, Zhang MR, Cong N, Xu AQ, Shao JH: Evaluation of androgen receptor transcriptional activities of some pesticides in vitro. Toxicology. 2008 Jan 14;243(1-2):59-65. Epub 2007 Oct 2. The selected chemicals are three organophosphate pesticides including dichlorvos, parathion and trichlorphon, and two pyrethroid pesticides including permethrin and cypermethrin. |
2(0,0,0,2) | Details |
| 18586453 | Zhang J, Zhu W, Zheng Y, Yang J, Zhu X: The antiandrogenic activity of pyrethroid pesticides cyfluthrin and beta-cyfluthrin. Reprod Toxicol. 2008 Aug;25(4):491-6. Epub 2008 May 15. A stably transfected, androgen-responsive cell line, MDA-kb2, was used to determine the androgen receptor (AR) antagonistic effects of cyfluthrin and beta-cyfluthrin in vitro, and the Hershberger assay was utilized to detect the antiandrogenic potential of the two pyrethroids in vivo. Moreover, we also compared the antiandrogenic activities of cyfluthrin and beta-cyfluthrin to four structurally related pyrethoids: permethrin, cypermethrin, beta-cypermethrin and bifenthrin. |
1(0,0,0,1) | Details |