| Name | cholinesterase |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | fenitrothion |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 3727380 | Simeonov SP: [Toxicologic research on acute poisoning with fenitrothion (Agria 1050) in chickens]. Vet Med Nauki. 1986;23(2):39-42. Most characteristic were the drop of cholinesterase activity up to 71 per cent and the rise of blood sugar by 49 per cent. |
2(0,0,0,2) | Details |
| 10771584 | Nigg HN, Knaak JB: Blood cholinesterases as human biomarkers of organophosphorus pesticide exposure. Rev Environ Contam Toxicol. 2000;163:29-111. In some cases, P-450 isozymes catalyze the oxidative cleavage of P-O-aryl bonds (e.g., parathion, methyl parathion, fenitrothion, and diazinon) to form inactive water-soluble alkyl phosphates and aryl leaving groups that are readily conjugated with glucuronic or sulfuric acids and excreted. |
2(0,0,0,2) | Details |
| 17324630 | Corsi I, Pastore AM, Lodde A, Palmerini E, Castagnolo L, Focardi S: Potential role of cholinesterases in the invasive capacity of the freshwater bivalve, Anodonta woodiana (Bivalvia: Unionacea): a comparative study with the indigenous species of the genus, Anodonta sp. Comp Biochem Physiol C Toxicol Pharmacol. 2007 Apr;145(3):413-9. Epub 2007 Feb 1. Calculated IC (50) for fenitrothion and chlorpyrifos was in the range 10 (-6)-10 (-3) M in muscle of A. woodiana while a higher inhibition was observed for fenitrothion (10 (-7) M) and lower for chlorpyrifos (10 (-2) M) in the indigenous species Anodonta sp. |
2(0,0,0,2) | Details |
| 8027507 | Dementi B: Ocular effects of organophosphates: a historical perspective of Saku disease. J Appl Toxicol. 1994 Mar-Apr;14(2):119-29. Follow-up studies in animals performed in Japan using such agents as ethylthiometon, fenthion and fenitrothion demonstrate adverse effects of organophosphates on the visual system. An important question arising from this work is that of the role of cholinesterase inhibition in the etiology of the effects. |
2(0,0,0,2) | Details |
| 8107298 | Yamanaka S, Yoshida M, Yamamura Y, Nishimura M, Takaesu Y: [A study on acute organophosphorus poisoning--changes in the activity and isoenzyme patterns of serum cholinesterase in human poisoning]. Nippon Eiseigaku Zasshi. 1993 Dec;48(5):955-65. Fenitrothion, Malathion, Isoxathion, Pyridaphenthion and Trichlorfon, and studied on the changes in the activity and isoenzyme patterns of serum ChE after ingestion. |
2(0,0,0,2) | Details |
| 6662350 | Matkovics B, Szabo L, Ivan J, Gaal I: Some further data on the effects of two organophosphate pesticides on the oxidative metabolism in the liver. Gen Pharmacol. 1983;14(6):689-91. Sumithion is the most active cholinesterase inhibitor. |
2(0,0,0,2) | Details |
| 7299616 | Matsubara T, Horikoshi I: Difference in fenitrothion-inhibited rat plasma cholinesterase activities determined by delta pH-method and DTNB-method, due to spontaneous reactivation. J Pharmacobiodyn. 1981 Jul;4(7):497-504. |
87(1,1,2,2) | Details |
| 9080632 | Yamashita M, Yamashita M, Tanaka J, Ando Y: Human mortality in organophosphate poisonings. Vet Hum Toxicol. 1997 Apr;39(2):84-5. Fenitrothion, malathion, dichlorvos, trichlorfon and fenitrothion/malathion were the most frequent chemicals involved. About 3/4 of the severely serum cholinesterase-depressed cases needed ventilators. |
2(0,0,0,2) | Details |
| 18771337 | Fildes K, Astheimer LB, Buttemer WA: The effect of acute fenitrothion exposure on a variety of physiological indices, including avian aerobic metabolism during exercise and cold exposure. Environ Toxicol Chem. 2009 Feb;28(2):388-94. The effect of fenitrothion exposure on birds was examined by measuring aerobic metabolism, blood hemoglobin content, plasma cholinesterases, and body weight for up to 21 d postdose. |
84(1,1,1,4) | Details |
| 6814874 | Liska D, Kolesar D, Hladka A, Valkyova I, Raiskup JC: Clinical and laboratory findings in Metation EK-50. Czech Med. 1982;5(3):146-54. From among the biochemical parameters after the exposure to fenitrothion the following ones can be mentioned: inhibition of cholinesterase in blood, increase of GPT transaminase, increase of insoenzyme LDH5 and changes in protein fractions, as statistically significant (P less than 0,001). |
81(1,1,1,1) | Details |
| 1178696 | Klaverkamp JF, Hobden BR, Harrison SE: Acute lethality and in vitro brain cholinesterase inhibition of acephate and fenitrothion in rainbow trout. Proc West Pharmacol Soc. 1975;18:358-61. |
81(1,1,1,1) | Details |
| 56273 | Freed VH, Matin MA, Fang SC, Kar PP: Role of striatal in delayed effects of organophosphorus compounds. Eur J Pharmacol. 1976 Jan;35(1):229-32. Fenitrothion neither produced motor dysfunction nor changed the level of striatal The cholinesterase activity of corpus striatum was inhibited by all the compounds. |
1(0,0,0,1) | Details |
| 680858 | Malik JK, Gupta RC, Paul BS: In vitro study on the comparative inhibitory effect of malathion, sumithion & hinosan on blood cholinesterase of Bubalus bubalis. Indian J Exp Biol. 1978 Apr;16(4):496-7. |
1(0,0,0,1) | Details |
| 7434367 | Trottier B, Fraser AR, Planet G, Ecobichon DJ: Subacute toxicity of technical fenitrothion in male rats. Toxicology. 1980;17(1):29-38. The brain plasma and erythrocyte cholinesterases, hepatic and renal non-specific carboxylesterases were assayed. |
1(0,0,0,1) | Details |
| 17701701 | Farghaly M, Mahdy F, Taha H, Fathy U: Behavior of the organophosphorus insecticide fenitrothion in stored faba beans and its biological effects towards experimental animals. J Environ Sci Health B. 2007 Aug;42(6):655-62. Feeding mice for 90 days with a diet mixed with total internal fenitrothion residues in stored faba beans led to a reduction in body weight gain, and an appreciable decrease in cholinesterase activity of 32% for plasma and 15% for red blood cells (RBC (S)) after two months of experiment. |
81(1,1,1,1) | Details |
| 12611659 | Meaklim J, Yang J, Drummer OH, Killalea S, Staikos V, Horomidis S, Rutherford D, Ioannides-Demos LL, Lim S, McLean AJ, McNeil JJ: Fenitrothion: toxicokinetics and toxicologic evaluation in human volunteers. Environ Health Perspect. 2003 Mar;111(3):305-8. On days 1 and 4, blood and urine samples were collected for analysis of fenitrothion and its major metabolites, as well as plasma and red blood cell cholinesterase activities, and biochemistry and hematology examination. |
81(1,1,1,1) | Details |
| 20143730 | Lajmanovich RC, Attademo AM, Peltzer PM, Junges CM: Inhibition and recovery of cholinesterases in Odontophrynus americanus tadpoles exposed to fenitrothion. J Environ Biol. 2009 Sep;30(5 Suppl):923-6. |
37(0,1,2,2) | Details |
| 14768874 | Bain D, Buttemer WA, Astheimer L, Fildes K, Hooper MJ: Effects of sublethal fenitrothion ingestion on cholinesterase inhibition, standard metabolism, thermal preference, and prey-capture ability in the Australian central bearded dragon (Pogona vitticeps, Agamidae). Environ Toxicol Chem. 2004 Jan;23(1):109-16. |
33(0,1,1,3) | Details |
| 1205634 | Hladka A, Krampl V: Effect of S-methylfenitrothion on the activity of cholinesterase and on the excretion of its metabolites in rats. Int Arch Occup Environ Health. 1975 Nov 4;36(1):67-73. |
1(0,0,0,1) | Details |
| 3874716 | Warren M, Spencer HC, Churchill FC, Francois VJ, Hippolyte R, Staiger MA: Assessment of exposure to organophosphate insecticides during spraying in Haiti: monitoring of urinary metabolites and blood cholinesterase levels. Bull World Health Organ. 1985;63(2):353-60. |
1(0,0,0,1) | Details |
| 8123995 | Villar D, Gonzalez M, Gualda MJ, Schaeffer DJ: Effects of organophosphorus insecticides on Dugesia tigrina: cholinesterase activity and head regeneration. Bull Environ Contam Toxicol. 1994 Feb;52(2):319-24. |
1(0,0,0,1) | Details |
| 18966276 | Kumaran S, Morita M: Application of a cholinesterase biosensor to screen for organophosphorus pesticides extracted from soil. Talanta. 1995 Apr;42(4):649-55. Based on the principle of enzyme inactivation, a butyrylcholinesterase (EC 3.1.1.8.) biosensor, to determine some organophosphorus (ORP) pesticides (Fenitrothion, Diazinon, Parathion ethyl, Mevinphos and Heptenophos) in soil extracts, is presented. |
32(0,1,1,2) | Details |
| 17178631 | Sochaski MA, McManus BM, Struve MF, Wallace DG, Dorman DC: Inhibition and recovery of maternal and foetal cholinesterase enzymes following fenitrothion administration in CD rats. Xenobiotica. 2007 Jan;37(1):19-29. |
31(0,1,1,1) | Details |
| 6726618 | Matsubara T, Horikoshi I: Chemical reactivations of inactivated acetylcholinesterase after 2-PAM therapy in fenitrothion-poisoned rat and rabbit. J Pharmacobiodyn. 1984 Feb;7(2):131-7. By single treatment with 2-PAM carried out immediately after fenitrothion administration, the significant reactivations of inactivated AChE in red blood cell (RBC) and brain as well as inactivated cholinesterase (ChE) in plasma were observed at 2 h after administration of 20 mg/kg fenitrothion in rat, while these reactivations became less in rats severely poisoned with 500 mg/kg fenitrothion. |
31(0,1,1,1) | Details |
| 15590106 | Okahashi N, Sano M, Miyata K, Tamano S, Higuchi H, Kamita Y, Seki T: Lack of evidence for endocrine disrupting effects in rats exposed to fenitrothion in utero and from weaning to maturation. Toxicology. 2005 Jan 5;206(1):17-31. In the P generation, brain cholinesterase activity was remarkably reduced in the 60 ppm males and in the 20 and 60 ppm females. |
1(0,0,0,1) | Details |
| 8897085 | Futagami K, Tanaka N, Nishimura M, Tateishi H, Aoyama T, Oishi R: Relapse and elevation of blood urea in acute fenitrothion and malathion poisoning. Int J Clin Pharmacol Ther. 1996 Oct;34(10):453-6. In addition, erythrocyte cholinesterase (EChE) activities were more helpful to diagnose the development of relapse than plasma cholinesterase activities. |
1(0,0,0,1) | Details |
| 11097804 | Kim YA, Lee HS, Park YC, Lee YT: A convenient method for oxidation of organophosphorus pesticides in organic solvents. Environ Res. 2000 Nov;84(3):303-9. Since organophosphorus pesticides can be oxidized to oxons in vivo and in the environment and their determination based on inhibition of cholinesterases can be more sensitive after their oxidation to oxons, development of an efficient method for their in vitro oxidation is important for their toxicological and analytical studies. Inhibition calibration curves for both unoxidized and oxidized forms of fenitrothion and parathion were obtained. |
1(0,0,0,1) | Details |
| 2086312 | Schop RN, Hardy MH, Goldberg MT: Comparison of the activity of topically applied pesticides and the herbicide 2,4-D in two short-term in vivo assays of genotoxicity in the mouse. Fundam Appl Toxicol. 1990 Nov;15(4):666-75. Serum cholinesterase levels were reduced to 70 +/- 4.7% of the DMSO control level with DDVP, 57 +/- 8.2% with aminocarb, and 60.3 +/- 4.8% with fenitrothion, indicating some systemic activity with these topically applied agents. |
31(0,1,1,1) | Details |
| 6631110 | El Sawaf BM, Rady MH: In situ inhibition of cholinesterase in Anopheles pharoensis and Culex pipiens by malathion and fenitrothion. J Egypt Soc Parasitol. 1983 Jun;13(1):43-7. |
31(0,1,1,1) | Details |
| 17089720 | Fildes K, Astheimer LB, Story P, Buttemer WA, Hooper MJ: Cholinesterase response in native birds exposed to fenitrothion during locust control operations in eastern Australia. Environ Toxicol Chem. 2006 Nov;25(11):2964-70. |
13(0,0,2,3) | Details |
| 3368670 | Ishimatsu S, Igisu H, Tanaka I, Inoue N, Akiyama T: [Effects of repeated inhalation-exposure to fenitrothion powder on blood cholinesterase activity in rats]. J UOEH. 1988 Mar 1;10(1):71-5. |
12(0,0,2,2) | Details |
| 10421485 | Satoh T, Suzuki S, Kawai N, Nakamura T, Hosokawa M: Toxicological significance in the cleavage of esterase-beta-glucuronidase complex in liver microsomes by organophosphorus compounds. Chem Biol Interact. 1999 May 14;119-120:471-8. From these in vivo and in vitro data, it is concluded that increase of the plasma beta-G level after OP administration is much more sensitive biomarker than cholinesterase inhibition to acute intoxication of OPs and carbamates. The EG complex was easily dissociated by administration of OPs, i.e. fenitrothion, EPN, phenthionate, and bis-beta-nitrophenyl (BNPP), and resulting beta-G dissociated was released into blood, leading to the rapid and transient increase of plasma beta-G level with a concomitant decrease of liver microsomal beta-G level. |
1(0,0,0,1) | Details |
| 1697627 | Yoshikawa H, Yoshida M, Hara I: Electroretinographic changes induced by organophosphorus pesticides in rats. J Toxicol Sci. 1990 May;15(2):87-95. Male Wistar rats were intraperitoneally injected with fenthion, chlorpyrifos, fenitrothion, dichlorvos or chlorfenvinphos at doses of 0.01 mmol/kg and/or 0.05 mmol/kg. The electroretinogram (ERG) was recorded at 5 hours and 2 days after the administration, and brain and retinochoroid cholinesterase (ChE) activities was assayed at 3 days after the injections. |
1(0,0,0,1) | Details |
| 3438612 | Ishimatsu S, Igisu H, Tanaka I, Inoue N, Akiyama T: [The inhaled effects of fenitrothion powder on blood cholinesterase in rats]. J UOEH. 1987 Dec 1;9(4):379-83. |
12(0,0,2,2) | Details |
| 8241478 | Fakhri ZI: Cholinesterase assessment as a result of fenitrothion exposure: a survey in a group of public health workers exposed to an organophosphorus pesticide. Occup Med. 1993 Nov;43(4):197-202. |
10(0,0,1,5) | Details |
| 7097808 | Yamamoto T, Egashira T, Yoshida T, Kuroiwa Y: Comparison of the effect of an equimolar and low dose of fenitrothion and methylparathion on their own metabolism in rat liver. J Toxicol Sci. 1982 Feb;7(1):35-41. The effects of fenitrothion and methylparathion on the activities of cholinesterase and hepatic microsomal monooxygenases were investigated and compared following a single or repeated oral administration of an equimolar and low dose of the insecticides. |
7(0,0,1,2) | Details |
| 2602857 | Tyburczyk W, Borkowska J, Klimek K, Galicki D: [Effect of the combined action of and fenitrothion on certain biochemical parameters in rat blood]. Rocz Panstw Zakl Hig. 1989;40(1):58-64. decreased the activity of glucose-6-phosphate dehydrogenase and with an increase of the activity of superoxide dismutase and protein SH groups and methaemoglobin level. fenitrothion caused similar changes as and decreased the activity of choline esterase and the level of |
7(0,0,1,2) | Details |
| 8812182 | Escartin E, Porte C: Acetylcholinesterase inhibition in the crayfish Procambarus clarkii exposed to fenitrothion. Ecotoxicol Environ Saf. 1996 Jul;34(2):160-4. Acetyl- and butyryl-cholinesterase activities were measured in the muscle of P. clarkii exposed to different doses of fenitrothion (4, 20, and 100 microg/liter) for different times (up to 48 hr). |
7(0,0,1,2) | Details |
| 7747323 | Bouma MJ, Nesbit R: Fenitrothion intoxication during spraying operations in the malaria programme for Afghan refugees in North West Frontier Province of Pakistan. Trop Geogr Med. 1995;47(1):12-4. A few weeks after commencement of the spraying operations, cholinesterase levels had fallen to 43.8% in personnel mixing the insecticide, and to 60.7% in spraymen, as measured by tintometry. |
1(0,0,0,1) | Details |
| 18584365 | Inoue S, Saito T, Suzuki Y, Iizuka S, Takazawa K, Akieda K, Yamamoto I, Inokuchi S: Prognostic factors and toxicokinetics in acute fenitrothion self-poisoning requiring intensive care. Clin Toxicol. 2008 Jul;46(6):528-33. We compared the characteristics, initial vital signs, physiological scores, corrected QT interval on electrocardiogram and laboratory data (serum fenitrothion concentration and cholinesterase activity) of non-survivors and survivors. |
6(0,0,1,1) | Details |
| 612605 | Khanna RN, Misra D, Hasan MZ: Effect of fenitrothion on level and cholinesterase activity in rats. Indian J Physiol Pharmacol. 1977 Jul-Sep;21(3):209-10. |
6(0,0,1,1) | Details |
| 3590223 | Malik JK, Srivastava AK: Effects of cholinesterase reactivators and atropine on fenitrothion-induced hypothermia in Bubalus bubalis. Toxicol Lett. 1987 May;36(3):289-95. |
6(0,0,1,1) | Details |
| 8511793 | Veronesi B, Ehrich M: Differential cytotoxic sensitivity in mouse and human cell lines exposed to organophosphate insecticides. Toxicol Appl Pharmacol. 1993 Jun;120(2):240-6. Baseline activities of the major target esterases, i.e., cholinesterase, carboxylesterase, and neurotoxic esterase, were assayed in mouse and several human neural candidate cell lines. IC50 data indicated that the tested mouse cell line was consistently more sensitive than the human cell line to equimolar doses of various OP compounds (e.g., mipafox, parathion, paraoxon, DFP, leptophos oxon, fenthion, and fenitrothion). |
1(0,0,0,1) | Details |
| 3590218 | Malik JK, Srivastava AK: Studies on the interaction between and fenitrothion in rats. Toxicol Lett. 1987 May;36(3):221-6. Oral administration of FTH (260 mg/kg) markedly inactivated cholinesterase (ChE) and carboxylesterase and elevated the activities of acid phosphatase, alanine aminotransferase and aspartate aminotransferase in different tissues 3 h after dosing. |
1(0,0,0,1) | Details |
| 3663986 | Busby DG, Pearce PA, Garrity NR: Effect of ultra ULV fenitrothion spraying on brain cholinesterase activity in forest songbirds. Bull Environ Contam Toxicol. 1987 Aug;39(2):304-11. |
6(0,0,1,1) | Details |
| 3820777 | Shimada E, Yoshida M, Yamanaka S, Aoyama H, Yamamura Y: [Erythrocyte and plasma cholinesterase activities on poisoning by disyston, fenitrothion and malathion] Sangyo Igaku. 1986 Sep;28(5):368-9. |
6(0,0,1,1) | Details |
| 2593091 | Audegond L, Catez D, Foulhoux P, Fournex R, Le Rumeur C, L'Hotellier M, Stepniewski JP: [Potentiation of deltamethrin toxicity by organophosphorus insecticides] . J Toxicol Clin Exp. 1989 May-Jun;9(3):163-76. It was demonstrated that some of them (azinphos, dichlorvos, dimethoate, fenitrothion, omethoate) induce an increase of toxicity of deltamethrin. Cholinesterase inhibitors of the group are ineffective. |
1(0,0,0,1) | Details |
| 2032000 | Abiola FA, Houeto P, Diatta F, Badiane M, Fayomi B: Agricultural organophosphate applicators cholinesterase activity and lipoprotein metabolism. Bull Environ Contam Toxicol. 1991 Mar;46(3):351-60. |
1(0,0,0,1) | Details |
| 6860145 | Yamamoto T, Egashira T, Yoshida T, Kuroiwa Y: Effect of adrenalectomy, pretreatment with SKF 525-A, phenobarbital and diethyl on the acute toxicity of fenitrothion in male rats. Arch Toxicol. 1983 Mar;52(3):233-42. The effect of adrenalectomy (Adx), SKF 525-A, phenobarbital (PB), and diethyl (DEM) on the acute toxicity of fenitrothion was investigated in male rats by assessing the degree of plasma cholinesterase activity. |
6(0,0,1,1) | Details |
| 3772007 | Coulombe PA, Lortie S, Cote MG, Chevalier G: Pulmonary toxicity of the insecticide fenitrothion in the rat following a single field exposure. J Appl Toxicol. 1986 Oct;6(5):317-23. Plasma pseudocholinesterase activity and pulmonary alveoli ultrastructure were used as indices to the fenitrothion exposure. |
6(0,0,1,1) | Details |
| 7284638 | Busby DG, Pearce PA, Garrity NR: Brain cholinesterase response in songbirds exposed to experimental fenitrothion spraying in New Brunswick, Canada. Bull Environ Contam Toxicol. 1981 Mar;26(3):401-6. |
6(0,0,1,1) | Details |
| 17713226 | Barata C, Damasio J, Lopez MA, Kuster M, Lopez de Alda M, Barcelo D, Riva MC, Raldua D: Combined use of biomarkers and in situ bioassays in Daphnia magna to monitor environmental hazards of pesticides in the field. Environ Toxicol Chem. 2007 Feb;26(2):370-9. The results obtained indicated high levels of pesticides in water, with peak values of 487 microg/L for bentazone, 8 microg/L for methyl-4-chlorophenoxyacetic acid, 5 microg/L for propanil, 0.8 microg/L for molinate, and 0.7 microg/L for fenitrothion. Measured biological responses denoted severe effects on grazing rates; a strong inhibition of cholinesterases and carboxylesterases, which are specific biomarkers of organophosphorous and pesticides; and altered patterns of the antioxidant enzyme catalase and the phase II metabolizing enzyme glutathione S-transferase. |
1(0,0,0,1) | Details |
| 9198006 | Yoshida A, Harada T, Maita K: A safety study on rat's eye after 13-week oral administration with fenitrothion. J Toxicol Sci. 1997 May;22(2):89-97. At termination of treatment, surviving animals were subjected to ophthalmoscopy, electroretinography, and biochemical analyses of plasma, erythrocyte, and brain cholinesterase (ChE). |
1(0,0,0,1) | Details |
| 18639607 | Farghaly M, El-Maghraby S: Toxicological evaluation and bioavailability of (14) C-fenitrothion bound residues on soybeans towards experimental animals. Food Chem Toxicol. 2008 Sep;46(9):3111-5. Epub 2008 Jun 29. The maximum inhibition in plasma and erythrocyte cholinesterase activity was observed 22.5%, 18.9% and 8.6%, 9% after one and seven days, respectively. |
1(0,0,0,1) | Details |
| 8295230 | Uehara S, Hiromori T, Isobe N, Suzuki T, Kato T, Miyamoto J: Studies on the therapeutic effect of 2- methiodide (2-PAM) in mammals following organophosphorus compound-poisoning (report III): distribution and antidotal effect of 2-PAM in rats. J Toxicol Sci. 1993 Nov;18(4):265-75. Intramedullary administration of 2-PAM to rats poisoned with fenitrothion or malathion enabled their survival and induced reactivation of brain cholinesterase. |
6(0,0,1,1) | Details |
| 6533340 | Yamanaka S, Nishimura M: [Effects of organophosphorus compounds and PAM on cholinesterase activity in rat tissues] Nippon Eiseigaku Zasshi. 1984 Dec;39(5):795-806. |
1(0,0,0,1) | Details |
| 4436402 | Kovac J, Markova V, Kralik P: Gas chromatographic determination of cholinesterase inhibition. J Chromatogr. 1974 Nov 13;100(1):171-4. |
1(0,0,0,1) | Details |
| 2777157 | Kojima T, Yashiki M, Miyazaki T, Chikasue F, Ohtani M: Detection of S-methylfenitrothion, aminofenitrothion, aminofenitroxon and acetylaminofenitroxon in the urine of a fenitrothion intoxication case. Forensic Sci Int. 1989 Jun;41(3):245-53. The serum cholinesterase activity (normal range: 175-440 I.U.) was only 29 at 3 h, 32 at 1 day, 59 at 2 days and 75 at 3 days after ingestion. |
1(0,0,0,1) | Details |
| 9478093 | Podolak M, Panasiuk L: Biological indicators for the assessment of human exposure to organophosphorous compounds. Przegl Lek. 1997;54(10):719-22. Cholinesterase activity in plasma and red blood cells was determined spectrophotometrically by the Ellman modified method. |
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| 18969806 | Solna R, Sapelnikova S, Skladal P, Winther-Nielsen M, Carlsson C, Emneus J, Ruzgas T: Multienzyme electrochemical array sensor for determination of phenols and pesticides. Talanta. 2005 Jan 30;65(2):349-57. The screen-printed four-electrode system was used as the amperometric transducer for determination of phenols and pesticides using immobilised tyrosinase, peroxidase, acetylcholinesterase and butyrylcholinesterase. The detection of and as well as of pesticides including carbaryl, heptenophos and fenitrothion was carried out in flow-through and steady state arrangements. |
3(0,0,0,3) | Details |
| 885596 | Anand M, Khanna RN, Misra D, Sharma HK: Changes in brain of rats after dermal application of fenitrothion (Sumithion). Indian J Physiol Pharmacol. 1977 Apr-Jun;21(2):124-4. Cholinesterase activity was measured in blood and brain. |
2(0,0,0,2) | Details |
| 3523965 | Simeonov SP, Borisov I: [Action of fenitrothion (Agria 1050) on the development of a surgical infection with Corynebacterium pyogenes in sheep]. Vet Med Nauki. 1986;23(1):42-7. Those of the second group developed the disease at a rapid course, with affection of the general state, atony of the forestomach, substantial changes in the hemopoiesis, the enzyme activity, the glycogenesis process, and the blood picture (erythropenia, drop of the hemoglobin content, higher erythrocyte sedimentation rate, leukocytosis with neutrophilia, strong drop of plasmal and serum cholinesterase, hyperglycaemia). |
1(0,0,0,1) | Details |
| 3224166 | Abiola FA, Sere A, Sawadogo JG, Diatta F, Ly M: Cholinesterase depression among Senegalese crop protection workers exposed to organophosphorous pesticides. Bull Environ Contam Toxicol. 1988 Oct;41(4):483-8. |
1(0,0,0,1) | Details |
| 8921343 | Kunimatsu T, Kamita Y, Isobe N, Kawasaki H: Immunotoxicological insignificance of fenitrothion in mice and rats. Fundam Appl Toxicol. 1996 Oct;33(2):246-53. |
0(0,0,0,0) | Details |
| 11201171 | Sunami O, Kunimatsu T, Yamada T, Yabushita S, Sukata T, Miyata K, Kamita Y, Okuno Y, Seki T, Nakatsuka I, Matsuo M: Evaluation of a 5-day Hershberger assay using young mature male rats: methyltestosterone and p,p'-DDE, but not fenitrothion, exhibited androgenic or antiandrogenic activity in vivo. J Toxicol Sci. 2000 Dec;25(5):403-15. |
0(0,0,0,0) | Details |
| 10227870 | Aprea C, Sciarra G, Sartorelli P, Ceccarelli F, Centi L: Multiroute exposure assessment and excretion of urinary metabolites of fenitrothion during manual operations on treated ornamental plants in greenhouses. Arch Environ Contam Toxicol. 1999 May;36(4):490-7. |
0(0,0,0,0) | Details |
| 8246310 | Uehara S, Hiromori T, Suzuki T, Kato T, Miyamoto J: Studies on the therapeutic effect of 2- methiodide (2-PAM) in mammals following organophosphorus compound (OP)-poisoning (report II): aging of OP-inhibited mammalian cholinesterase. J Toxicol Sci. 1993 Aug;18(3):179-83. We estimated the reactivation rate with 2-PAM following inhibition of ChE by fenitrothion, methylparathion or ethylparathion using erythrocytes of rat and rabbit and rat brain. |
2(0,0,0,2) | Details |
| 15311856 | Guven M, Sungur M, Eser B: The effect of plasmapheresis on plasma cholinesterase levels in a patient with organophosphate poisoning. Hum Exp Toxicol. 2004 Jul;23(7):365-8. |
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| 2975504 | Gun RT, Grycorcewicz C, Esterman AJ, Edwards JB: Ultralow volume application of organophosphate concentrate in grain terminals: a new occupational health hazard. Br J Ind Med. 1988 Dec;45(12):834-7. The introduction of ultralow volume (ULV) application of the organophosphate pesticide Fenitrothion in grain terminals presents a risk to workers of skin contact with concentrate. Blood testing, by the Ellman method, of a group of five grain terminal workers working on grain treatment showed a lowering of mean red blood cell cholinesterase (RBC ChE) activity to 23 units/gm Hb (normal value 28-40) with a range of 16-29. |
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| 7935147 | Aprea C, Sciarra G, Sartorelli P, Ceccarelli F, Maiorano M, Savelli G: [Evaluation of omethoate and fenitrothion absorption in greenhouse workers using protective equipment in confined areas]. Med Lav. 1994 May-Jun;85(3):242-8. |
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| 844021 | Ecobichon DJ, Ozere RL, Reid E, Crocker JF: Acute fenitrothion poisoning. Can Med Assoc J. 1977 Feb 19;116(4):377-9. Erythrocytic and plasma cholinesterase activities had been monitored prior to exposure and were monitored throughout treatment and following recovery. |
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| 7097482 | Matsubara T, Horikoshi I: Spontaneous reactivation of fenitro-oxon-inhibited plasma cholinesterase in various mammals. J Pharmacobiodyn. 1982 Mar;5(3):155-61. |
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