| Name | calmodulin |
|---|---|
| Synonyms | CALM; CAM; CALM 1; CALM 2; CALM 3; CALM1; CALM2; CALM3… |
| Name | fenvalerate |
|---|---|
| CAS | cyano(3-phenoxyphenyl)methyl 4-chloro-α-(1-methylethyl)benzeneacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9655866 | Huang RQ, Dillon GH: Maintenance of recombinant type A gamma-aminobutyric acid receptor function: role of protein phosphorylation and calcineurin. J Pharmacol Exp Ther. 1998 Jul;286(1):243-55. Inhibition of the Ca++/calmodulin-dependent phosphatase calcineurin with fenvalerate also prevented rundown of the response to |
81(1,1,1,1) | Details |
| 15363582 | He J, Chen J, Liu R, Wang S, Song L, Chang HC, Wang X: Alterations of FSH-stimulated production and homeostasis in primarily cultured human luteinizing-granulosa cells induced by fenvalerate. Toxicology. 2004 Oct 15;203(1-3):61-8. Due to and Ca2+ -calmodulin (CaM) system involving gonadotropin-stimulated steroidogenesis by granulosa cells, we then evaluated the effects of fenvalerate on trifluoperazine (TFP)- and -driven FSH-stimulated P4 production. |
37(0,1,2,2) | Details |
| 9587652 | Lippe C, Bellantuono V, Quaranta A, Castronuovo G, Cassano G, Ardizzone C: Cyclosporin A stimulates Na+ transport across the isolated skin of Rana esculenta. Arch Physiol Biochem. 1997 Oct;105(6):596-602. The Cs A effect on Na+ transport could be caused by an inhibition of a Ca2+/calmodulin-dependent protein phosphatase, i.e. calcineurin, since: a) it is mimicked by another inhibitor of calcineurin, i.e. fenvalerate: b) the action of Cs A and fenvalerate on SCC are decreased by the calmodulin inhibitor W7. |
31(0,1,1,1) | Details |
| 9714322 | Fakata KL, Swanson SA, Vorce RL, Stemmer PM: Pyrethroid insecticides as phosphatase inhibitors. . Biochem Pharmacol. 1998 Jun 15;55(12):2017-22. The type II pyrethroid insecticides cis-cypermethrin (c-Cyp), trans-cypermethrin, deltamethrin (Delt), and fenvalerate A alpha (Fen), as well as the type I pyrethroid insecticides cis- and trans-permethrin and S-bioallethrin, were unable to inhibit the phosphatase activity of purified calcineurin under conditions of maximal activation by Ca2+ and calmodulin. |
31(0,1,1,1) | Details |
| 16673813 | He J, Chen JF, Liu R, Song L, Chang HC, Wang XR: Fenvalerate-induced alterations in homeostasis in rat ovary. . Biomed Environ Sci. 2006 Feb;19(1):15-20. The activities of phosphorylase a enhanced in all treated groups, and fenvalerate increased the total content of calmodulin significantly in estrus period. |
7(0,0,1,2) | Details |
| 1315545 | Enan E, Matsumura F: Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides. Biochem Pharmacol. 1992 Apr 15;43(8):1777-84. The inhibitory action of synthetic pyrethroids and some chlorinated hydrocarbon insecticides on the neural -calmodulin-dependent protein phosphatase, calcineurin, was studied using one radiotracer and two colorimetric methods. It was found that all insecticidal Type II pyrethroids (cypermethrin, deltamethrin and fenvalerate) are potent inhibitors of isolated calcineurin from bovine brain. |
1(0,0,0,1) | Details |
| 14989895 | He J, Chen JF, Liu R, Wang YB, Wang XR: [Effect of fenvalerate on the ovarian homeostasis and the serum steroid hormone]. Zhonghua Yu Fang Yi Xue Za Zhi. 2004 Jan;38(1):18-21. The activity of ovarian Ca (2+)-ATPase and phosphorylase A (P-a) and the contents of calmodulin (CaM) were assessed after a 30-day Fen exposure. |
1(0,0,0,1) | Details |
| 9070464 | Victor RG, Rusnak F, Sikkink R, Marban E, O'Rourke B: Mechanism of Ca (2+)-dependent inactivation of L-type Ca2+ channels in GH3 cells: direct evidence against dephosphorylation by calcineurin. J Membr Biol. 1997 Mar 1;156(1):53-61. Similarly, blocking calmodulin activation with calmidazolium or blocking calcineurin with fenvalerate did not influence the extent of Ca (2+)-dependent inactivation after photolysis. |
0(0,0,0,0) | Details |