| 10799337 |
Ledirac N, Delescluse C, Lesca P, Piechocki MP, Hines RN, de Sousa G, Pralavorio M, Rahmani R: Diflubenzuron, a benzoyl-urea insecticide, is a potent inhibitor of TCDD-induced CYP1A1 expression in HepG2 cells. Toxicol Appl Pharmacol. 2000 May 1;164(3):273-9.
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87(1,1,1,7) |
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| 9820645 |
Delescluse C, Ledirac N, de Sousa G, Pralavorio M, Lesca P, Rahmani R: Cytotoxic effects and induction of cytochromes P450 1A1/2 by insecticides, in hepatic or epidermal cells: binding capability to the Ah receptor. Toxicol Lett. 1998 Aug;96-97:33-9.
We therefore tested the comparative acute and chronic toxicity of chemicals belonging to the major insecticides families (DDT, malathion and tetrachlorvinphos, carbaryl, cypermethrin, diflubenzuron), in hepatocytes, HepG2 and HaCaT cell lines.
Two kinds of end-points were used: cytotoxicity parameters and CYP1A1 induction. |
1(0,0,0,1) |
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