Protein Information

Name ATPase
Synonyms ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1…

Compound Information

Name dimethoate
CAS

Reference List

PubMed Abstract RScore(About this table)
11985885 Yang D, Lu X, Zhang W, He F: Biochemical changes in primary culture of skeletal muscle cells following dimethoate exposure. Toxicology. 2002 May 24;174(2):79-85.

Dimethoate can significantly increase the activity of Na+-K+-ATPase in the mitochondrial and cytoplasm fraction of muscle cells, and inhibit the activity of Ca2+-ATPase.
112(1,2,2,2) Details
2973491 Shaker N, Hassan GA, el-Nouty FD, Abo-Elezz Z, Abd-Allah GA: In vivo chronic effect of dimethoate and deltamethrin on rabbits. J Environ Sci Health B. 1988 Aug;23(4):387-99.

Dimethoate inhibited ATPase particularly at the end of treatment in a dose dependent manner.
88(1,1,2,3) Details
16872049 Singh M, Sandhir R, Kiran R: Erythrocyte antioxidant enzymes in toxicological evaluation of commonly used organophosphate pesticides. Indian J Exp Biol. 2006 Jul;44(7):580-3.

Present work is designed to study the in vitro effects of some organophosphates (ethion, chlorpyrifos, dimethoate and monocrotophos) on rat erythrocytes.
Membrane bound enzymes like acetylcholinesterase (AChE), Na (+)-K (+)-ATPase and Ca (2+)-ATPase were also inhibited.
1(0,0,0,1) Details