dimethoate
Identification (Source:EPA,EU)
| ID | 215 |
|---|---|
| Name | dimethoate |
| CAS | 60-51-5 |
| IUPAC | |
| Inchi | InChI=1S/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) |
| CIPAC | 59 |
| EPA Code | 035001 |
| Formula | C5H12NO3PS2 |
| SMILES | O=C(NC)CSP(=S)(OC)OC |
| Status | Approved |
Classification
| Mode of Action | Systemic with contact and stomach action. Acetylcholinesterase (AChE) inhibitor. |
|---|---|
| Pesticide Type | Insecticide, Acaricide, Metabolite |
| Chemical Group | Organophosphate |
| Classification |
organothiophosphate nematicides aliphatic organothiophosphate insecticides aliphatic amide organothiophosphate insecticides organothiophosphate acaricides organothiophosphate insecticides |
Properties (Source:PubChem)
| Molecular Weight | 229.26 |
|---|---|
| Physical State | Grey to white coloured crystals |
| AlogP | 0.352 |
| H-Bond Donor | 1 |
| H-Bond Acceptor | 5 |
| Surface Area | 228.32 |
| Polar Surface Area | 114.76 |
Structure
ChemMapper Search Option (Docunmentation of ChemMapper)
Ecotoxicology (Source:PPDB,IPM)
| Species | Method | Study Time | Dose Type | Value |
|---|---|---|---|---|
| Algae | Acute | 72 hour | EC50, growth | 90.4 mg l-1 |
| Algae | Chronic | 96 hour | NOEC, growth | 32 mg l-1 |
| Aquatic crustaceans | Acute | 96 hour | LC50 | 15.0 mg l-1 |
| Aquatic invertebrates | Acute | 48 hour | EC50 | 2 mg l-1 |
| Aquatic invertebrates | Chronic | 21 day | NOEC | 0.04 mg l-1 |
| Birds | Short term dietary | LC50/LD50 | 14.8 mg/kq bw/day | |
| Birds | Acute | LD50 | 10.5 mg kg-1 | |
| Earthworms | Chronic | 14 day | NOEC, reproduction | 2.87 mg kg-1 |
| Earthworms | Acute | 14 day | LD50 | 31 mg kg-1 |
| Fish | Chronic | 21 day | NOEC | 0.4 mg l-1 |
| Fish | Acute | 96 hour | LC50 | 30.2 mg l-1 |
| Honeybees | Acute | 48 hour | LD50 | 0.12 μg bee-1 |
| Mammals | Acute oral | LD50 | 245 mg kg-1 | |
| Mammals | Short term dietary | NOEL | 0.18 mg kg-1 | |
| Sediment dwelling organisms | Chronic | 28 day | NOEC, sediment | 0.08 mg kg-1 |
| Bio-concentration factor | CT50 | Not available days |
Related targets
| Target Name | RScore (About this table) | |
|---|---|---|
| Acetylcholinesterase | 1493(11,22,41,188) | Details |
| cholinesterase | 443(2,7,13,103) | Details |
| cytochrome P450 (protein family or complex) | 215(2,3,6,10) | Details |
| ATPase | 201(2,3,4,6) | Details |
| acetylcholine receptor (protein family or complex) | 199(2,3,4,4) | Details |
| brains | 118(1,2,2,8) | Details |
| muscles | 115(1,2,2,5) | Details |
| demethylase | 83(1,1,1,3) | Details |
| CYP2B | 81(1,1,1,1) | Details |
| thyroid stimulating hormone (protein family or complex) | 81(1,1,1,1) | Details |
| protein kinase A (protein family or complex) | 81(1,1,1,1) | Details |
| adenylate cyclase | 63(0,2,2,3) | Details |
| NA K ATPase | 62(0,2,2,2) | Details |
| CS2 | 34(0,1,1,4) | Details |
| estrogen receptor | 32(0,1,1,2) | Details |
| succinate dehydrogenase (protein family or complex) | 31(0,1,1,1) | Details |
| NF90 | 26(0,0,4,6) | Details |
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Node List
| ID | Name | Type |
|---|---|---|
Legend:
: Current entry node;
: Target node;
: Compound node;