Protein Information

Name muscles
Synonyms COX 7a M; COX VIIa M; COX7A; COX7A1; COX7A1 protein; COX7AH; COX7AM; Cytochrome c oxidase subunit 7a H…

Compound Information

Name dimethoate
CAS

Reference List

PubMed Abstract RScore(About this table)
719292 Buckley GA, Godden DH, Parrish SK: Motor output to flight muscles and inhibition of acetylcholinesterase after injection of dimethoate into locusts [proceedings] Br J Pharmacol. 1978 Nov;64(3):446P-447P.
81(1,1,1,1) Details
185861 Bleyer H, Moritz KU, Grisk A: [The effect of diisopropylfluorphosphate on the adenylate cyclase activity and the 3',5'-AMP content of myocardium and brain]. Acta Biol Med Ger. 1976;35(1):87-92.

Adenylate cyclase [ATP-pyrophosphatelyase (cyclizing) EC 4.6.1.1.] from ventricular muscles and the cerebrum of rats can be inhibited by diisopropylphosphofluoridate (DFP) and paraxone in concentrations from 10 (-7) - 10 (-9) M, and by dimethoate in concentrations from 10 (-5) - 10 (-7) M.
31(0,1,1,1) Details
1324992 De Bleecker J, Van Den Neucker K, Willems J: The intermediate syndrome in organophosphate poisoning: presentation of a case and review of the literature. J Toxicol Clin Toxicol. 1992;30(3):321-9; discussion 331-2.

A dimethoate-poisoned woman gradually developed a moderately severe cholinergic crisis that was readily treated by atropine.
After being symptom-free for nearly two days, she suffered from sudden life-threatening respiratory paresis and weakness of the facial, extraocular, neck flexor and proximal limb muscles.
1(0,0,0,1) Details
15041284 Sapozhnikova Y, Bawardi O, Schlenk D: Pesticides and PCBs in sediments and fish from the Salton Sea, California, USA. Chemosphere. 2004 May;55(6):797-809.

DDE concentrations in fish muscles tissues were above the 50 ng/g concentration threshold for the protection of predatory birds.
Dimethoate, diazinon, malathion, chlorpyrifos, disulfoton varied from < or = 0.15 to 9.5 ng/g dry wt in sediments and from < or = 0.1 to 80.3 ng/g wet wt in fish tissues.
1(0,0,0,1) Details
3029588 Senanayake N, Karalliedde L: Neurotoxic effects of organophosphorus insecticides. N Engl J Med. 1987 Mar 26;316(13):761-3.

We observed 10 patients who had paralysis of proximal limb muscles, neck flexors, motor cranial nerves, and respiratory muscles 24 to 96 hours after poisoning, after a well-defined cholinergic phase.
The compounds involved were fenthion, monocrotophos, dimethoate, and methamidophos.
1(0,0,0,1) Details