| PubMed |
Abstract |
RScore(About this table) |
| 19186174 |
Cabello CM, Bair WB 3rd, Ley S, Lamore SD, Azimian S, Wondrak GT: The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A (p21) upregulation in human cancer cell lines. Biochem Pharmacol. 2009 Apr 1;77(7):1125-38. Epub 2008 Dec 24.
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7(0,0,1,2) |
Details |
| 10884382 |
Jin YH, Yoo KJ, Lee YH, Lee SK: Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells. J Biol Chem. 2000 Sep 29;275(39):30256-63.
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5(0,0,0,5) |
Details |
| 9844631 |
Yu D, Jing T, Liu B, Yao J, Tan M, McDonnell TJ, Hung MC: Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase. Mol Cell. 1998 Nov;2(5):581-91.
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4(0,0,0,4) |
Details |
| 10660590 |
Romanowski P, Marr J, Madine MA, Rowles A, Blow JJ, Gautier J, Laskey RA: Interaction of Xenopus Cdc2 x cyclin A1 with the origin recognition complex. J Biol Chem. 2000 Feb 11;275(6):4239-43.
The kinase activity is sensitive to several inhibitors of cyclin-dependent kinases including 6-dimethylaminopurine (6-DMAP), olomoucine, and p21 (Cip1). |
1(0,0,0,1) |
Details |
| 15640940 |
Knillova J, Bouchal J, Hlobilkova A, Strnad M, Kolar Z: Synergic effects of the cyclin-dependent kinase (CDK) inhibitor olomoucine and androgen-antagonist bicalutamide on prostatic cancer cell lines. Neoplasma. 2004;51(5):358-67.
The proliferation arrest was accompanied by a decrease in cyclin D1 expression and the activation of p21Waf1/Cip1 and p27Kip1 pathways in both cell lines. |
1(0,0,0,1) |
Details |