| Name | cyclin dependent protein kinases |
|---|---|
| Synonyms | CDK 4; CDK4; CDK4 protein; CMM 3; CMM3; Cell division kinase 4; Cell division protein kinase 4; Cyclin dependent kinase 4… |
| Name | kinetin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16759516 | Tian DS, Wang W, Xu YL, Yu ZY, Xie MJ, Wang P, Zhang GB: [Effects of cyclin dependent protein kinase inhibitor olomoucine on the microenvironment of axonal regeneration after spinal cord injury: an experiment with rats]. Zhonghua Yi Xue Za Zhi. 2006 Apr 4;86(13):901-5. |
2(0,0,0,2) | Details |
| 17925171 | Du XP, Sun MZ, Yu ZY, Chen HX, Tian DS, Xie MJ, Wang W: [Effects of cyclin dependent protein kinase inhibitor olomoucine on the neuronal apoptosis after status epilepticus: experiment with rats]. Zhonghua Yi Xue Za Zhi. 2007 Aug 7;87(29):2025-9. |
2(0,0,0,2) | Details |
| 10717301 | Waters NC, Woodard CL, Prigge ST: Cyclin H activation and drug susceptibility of the Pfmrk cyclin dependent protein kinase from Plasmodium falciparum. Mol Biochem Parasitol. 2000 Mar 15;107(1):45-55. |
2(0,0,0,2) | Details |
| 8943149 | Graeser R, Wernli B, Franklin RM, Kappes B: Plasmodium falciparum protein kinase 5 and the malarial nuclear division cycles. Mol Biochem Parasitol. 1996 Nov 12;82(1):37-49. In the course of our studies on cell cycle regulation mechanisms of Plasmodium falciparum, we investigated expression pattern, kinase activity, and localization of PfPK5, a putative malarial member of the family of cyclin-dependent protein kinase (cdks). |
1(0,0,0,1) | Details |
| 9122166 | Kwon YG, Lee SY, Choi Y, Greengard P, Nairn AC: Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2168-73. The phosphorylation of T320 of PP-1 was reduced by the cyclin-dependent protein kinase inhibitor, olomoucine, and increased by the PP-1/PP-2A inhibitor, calyculin A. |
1(0,0,0,1) | Details |
| 11986377 | Furukawa T, Ogura T, Zheng YJ, Tsuchiya H, Nakaya H, Katayama Y, Inagaki N: Phosphorylation and functional regulation of ClC-2 channels expressed in Xenopus oocytes by M cyclin-dependent protein kinase. J Physiol. 2002 May 1;540(Pt 3):883-93. |
1(0,0,0,1) | Details |
| 7479711 | Schulze-Gahmen U, Brandsen J, Jones HD, Morgan DO, Meijer L, Vesely J, Kim SH: Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine. Proteins. 1995 Aug;22(4):378-91. |
1(0,0,0,1) | Details |
| 12534346 | Bain J, McLauchlan H, Elliott M, Cohen P: The specificities of protein kinase inhibitors: an update. Biochem J. 2003 Apr 1;371(Pt 1):199-204. Our results suggest that the combined use of Roscovitine and Kenpaullone may be useful for identifying substrates and physiological roles of cyclin-dependent protein kinases, whereas the combined use of Kenpaullone and LiCl may be useful for identifying substrates and physiological roles of glycogen synthase kinase 3. |
1(0,0,0,1) | Details |
| 14653808 | Penuelas S, Alemany C, Noe V, Ciudad CJ: The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors. Eur J Biochem. 2003 Dec;270(24):4809-22. To achieve this, we used the chemical inhibitors roscovitine and olomoucine (which inhibit CDK2 preferentially), UCN-01 (which also inhibits CDK4/6) and p21 (as an intrinsic inhibitor). |
1(0,0,0,1) | Details |