| Name | bcl 2 |
|---|---|
| Synonyms | Apoptosis regulator Bcl 2; B cell CLL/lymphoma 2; B cell lymphoma protein 2 alpha; B cell lymphoma protein 2 alpha isoform; BCL2; Bcl 2; B cell CLL/lymphoma 2s; B cell lymphoma protein 2 alphas… |
| Name | methoxychlor |
|---|---|
| CAS | 1,1′-(2,2,2-trichloroethylidene)bis[4-methoxybenzene] |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16081520 | Miller KP, Gupta RK, Greenfeld CR, Babus JK, Flaws JA: Methoxychlor directly affects ovarian antral follicle growth and atresia through Bcl-2- and Bax-mediated pathways. Toxicol Sci. 2005 Nov;88(1):213-21. Epub 2005 Aug 4. |
36(0,1,1,6) | Details |
| 14973267 | Borgeest C, Miller KP, Gupta R, Greenfeld C, Hruska KS, Hoyer P, Flaws JA: Methoxychlor-induced atresia in the mouse involves Bcl-2 family members, but not gonadotropins or Biol Reprod. 2004 Jun;70(6):1828-35. Epub 2004 Feb 18. Because Bcl-2 (an antiapoptotic factor), Bax (a proapoptotic factor), gonadotropins, and are important regulators of atresia in the ovary, the purpose of this study was first to examine whether MXC-induced atresia occurred through alterations in Bcl-2 or Bax, and second, to examine the effect of MXC on gonadotropins, and their receptors. |
5(0,0,0,5) | Details |
| 15525693 | Symonds DA, Tomic D, Miller KP, Flaws JA: Methoxychlor induces proliferation of the mouse ovarian surface epithelium. Toxicol Sci. 2005 Feb;83(2):355-62. Epub 2004 Nov 3. Expression of bcl-2 was significantly increased in MXC- and HPTE-treated cells, while bax was decreased in MXC- and HPTE-treated cells compared to controls. |
1(0,0,0,1) | Details |