| Name | calcitonin gene related peptide |
|---|---|
| Synonyms | Alpha type CGRP; CT; CGRP; CALC 1; CALC1; CALCA; CGRP 1; CGRP I… |
| Name | benzalkonium chloride |
|---|---|
| CAS | quaternary ammonium compounds, alkylbenzyldimethyl, chlorides |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2417614 | Piotrowski W, Foreman JC: Some effects of calcitonin gene-related peptide in human skin and on release. Br J Dermatol. 1986 Jan;114(1):37-46. The substance P analogue, [D-Pro4, D-Trp7,9,10] SP4-11 10 microM, and benzalkonium chloride 10 microM inhibited release from rat mast cells stimulated by either CGRP or substance P. |
85(1,1,1,5) | Details |
| 20162407 | Kaur R, O'Shaughnessy CT, Jarvie EM, Winchester WJ, McLean PG: Characterization of a calcitonin gene-related peptide release assay in rat isolated distal colon. Arch Pharm Res. 2009 Dec;32(12):1775-81. Epub 2010 Feb 17. The mast cell degranulator, compound 48/80 significantly increased CGRP release an effect that was blocked in the presence of the mast cell stabilizer, ketotifen and the selective Gi inhibitor benzalkonium chloride. |
37(0,1,1,7) | Details |
| 10985629 | Wallengren J: Dual effects of CGRP-antagonist on allergic contact dermatitis in human skin. Contact Dermatitis. 2000 Sep;43(3):137-43. The patients were also provoked with tuberculin (delayed immunologic reaction), benzalkonium chloride (irritant contact dermatitis), UV-light and (non-immunologic contact urticaria). |
4(0,0,0,4) | Details |
| 9274467 | Higham A, Vaillant C, Yegen B, Thompson DG, Dockray GJ: Relation between cholecystokinin and antral innervation in the control of gastric emptying in the rat. Gut. 1997 Jul;41(1):24-32. Benzalkonium chloride (BAC) causes selective lesions in gut myenteric neurons after serosal application. RESULTS: In BAC treated rats radioimmunoassay of tissue extracts revealed a dose related specific loss of gastrin releasing peptide, substance P, and vasoactive intestinal polypeptide immunoreactivities from the treated region, and immunohistochemistry revealed loss of the neuronal marker PGP 9.5 and the afferent neuropeptide calcitonin gene related peptide (CGRP). |
2(0,0,0,2) | Details |
| 1361543 | Braga PC, Piatti G, Dal Sasso M, Bernini A: The effects of calcitonin nasal preparations and their excipients on mucociliary clearance in an ex-vivo frog palate test. J Pharm Pharmacol. 1992 Nov;44(11):938-40. The topical tolerability of the commercial preparation of 1-7 Asu-eel and salmon calcitonin with 2% ammonium glycyrrhyzinate and 0.01% benzalkonium chloride, respectively, and of their excipients mixture in solution with increasing concentrations of ammonium glycyrrhyzinate and benzalkonium chloride, respectively, were assessed by investigating their effects on the mucociliary transport velocity in the ex-vivo frog palate preparation. |
1(0,0,0,1) | Details |