Protein Information

Name SARS
Synonyms SARS; SERS; Serine tRNA ligase; SARS 2; SARS2; SARSM; SYS; SerRSmt…

Compound Information

Name formaldehyde
CAS formaldehyde

Reference List

PubMed Abstract RScore(About this table)
17515642 Tsunetsugu-Yokota Y, Ato M, Takahashi Y, Hashimoto S, Kaji T, Kuraoka M, Yamamoto K, Mitsuki YY, Yamamoto T, Oshima M, Ohnishi K, Takemori T: Formalin-treated UV-inactivated SARS coronavirus vaccine retains its immunogenicity and promotes Th2-type immune responses. Jpn J Infect Dis. 2007 May;60(2-3):106-12.

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19045112 Xia L, Wang H, Wang J, Gong K, Jia Y, Zhang H, Sun M: Microwave-assisted synthesis of sensitive silver substrate for surface-enhanced Raman scattering spectroscopy. J Chem Phys. 2008 Oct 7;129(13):134703.

A sensitive silver substrate for surface-enhanced Raman scattering (SERS) spectroscopy is synthesized under multimode microwave irradiation.
Formaldehyde was employed as both the reductant and microwave absorber in the reductive process.
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19094399 Cheng ML, Yang J: Influences of composition on electroless deposition of silver nanoparticles on glass substrates for surface-enhanced Raman scattering measurements. Appl Spectrosc. 2008 Dec;62(12):1384-94.

A silver-mirror reaction was used to prepare active substrates for surface-enhanced Raman scattering (SERS).
Reducing agents included formaldehyde, sodium tartrate, and several carbohydrates.
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18071064 Lutz B, Dentinger C, Sun L, Nguyen L, Zhang J, Chmura A, Allen A, Chan S, Knudsen B: Raman nanoparticle probes for antibody-based protein detection in tissues. J Histochem Cytochem. 2008 Apr;56(4):371-9. Epub 2007 Dec 10.


Surface-enhanced Raman scattering (SERS) nanoparticles are emerging as a new approach for optical detection of biomolecules.
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17705409 Tan S, Erol M, Attygalle A, Du H, Sukhishvili S: Synthesis of positively charged silver nanoparticles via photoreduction of AgNO3 in branched polyethyleneimine/HEPES solutions. Langmuir. 2007 Sep 11;23(19):9836-43. Epub 2007 Aug 17.

The mechanism for the reduction of Ag+ ions in the BPEI/HEPES mixtures entails oxidative cleavage of BPEI chains that results in the formation of positively charged BPEI fragments enriched with amide groups as well as in the production of formaldehyde, which serves as a reducing agent for Ag+ ions.
Importantly, these positively charged Ag nanoparticles demonstrate superior SERS activity over negatively charged citrate reduced Ag nanoparticles for the detection of thiocyanate and perchlorate ions; therefore, they are promising candidates for sensing and detection of a variety of negatively charged analytes in aqueous solutions using surface-enhanced Raman spectroscopy (SERS).
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18095180 Kuo NW, Chiang HC, Chiang CM: Development and application of an integrated indoor air quality audit to an international hotel building in Taiwan. Environ Monit Assess. 2008 Dec;147(1-3):139-47. Epub 2007 Dec 20.

In addition, microbial pollution can affect the health of tourists such as the Legionnaire's disease and SARS problems.
They are: (1) low room temperature (21.8 degrees C), (2) insufficient air exchange rate (<1.5 h (-1)), (3) formaldehyde contamination (> 0.02 ppm), and (4) the microbial pollution (total bacteria: 2,624-3,799 CFU/m (3)).
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