formaldehyde

Identification (Source:EPA,EU)

ID 348
Name formaldehyde
CAS 50-00-0
IUPAC formaldehyde
Inchi InChI=1S/CH2O/c1-2/h1H2
CIPAC 156
EPA Code 043001
Formula CH2O
SMILES C=O
Status Not Approved

Classification

Mode of Action Acts by protein denaturation
Pesticide Type Fungicide, Bactericide, Metabolite, Other product constituent
Chemical Group Unclassified
Classification Bactericides
unclassified fungicides

Properties (Source:PubChem)

Molecular Weight 30.03
Physical State Gas
AlogP -0.885
H-Bond Donor 0
H-Bond Acceptor 1
Surface Area 42.32
Polar Surface Area 17.07

Structure



ChemMapper Search Option (Docunmentation of ChemMapper)

3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 0.88 mg l-1
Aquatic invertebrates Acute 48 hour EC50 0.43 mg l-1
Birds Acute LD50 5000 mg kg-1
Fish Acute 96 hour LC50 1.84 mg l-1
Mammals Acute oral LD50 550 mg kg-1
Mammals Short term dietary NOEL 50 ppm diet
Bio-concentration factor CT50 Not available days

Related targets

Target Name RScore (About this table)
alcohol dehydrogenase 3 398(3,7,8,33) Details
formaldehyde dehydrogenase 334(2,5,14,39) Details
C18 166(2,2,2,6) Details
alcohol dehydrogenase (protein family or complex) 210(1,4,4,40) Details
semicarbazide sensitive amine oxidase 179(1,4,4,9) Details
capsaicin receptor 174(1,3,3,34) Details
ribonuclease A 157(1,3,5,7) Details
H2AX 113(1,2,2,3) Details
tumor necrosis factor alpha 107(1,1,1,27) Details
TRPA1 105(1,1,1,25) Details
aldehyde dehydrogenase (protein family or complex) 102(1,1,1,22) Details
catalase 90(1,1,1,10) Details
GSTP1 90(1,1,2,5) Details
CA2 89(1,1,1,9) Details
FOXA1 88(1,1,1,8) Details
MDM2 88(1,1,2,3) Details
calcyclin 87(1,1,2,2) Details
TFIIIC 85(1,1,1,5) Details
CREB 1 82(1,1,1,2) Details
origin recognition complex (protein family or complex) 82(1,1,1,2) Details
C48 82(1,1,1,2) Details
citrate synthase 82(1,1,1,2) Details
cytochrome P450 monooxygenase 81(1,1,1,1) Details
short chain acyl CoA dehydrogenase 81(1,1,1,1) Details
U2B 81(1,1,1,1) Details
d x 81(1,1,1,1) Details
NMDA receptor (protein family or complex) 122(0,3,3,32) Details
AlkB 109(0,3,3,19) Details
albumin 104(0,3,4,9) Details
IgE 100(0,3,4,5) Details
MP2 75(0,2,2,15) Details
interleukin 10 73(0,2,2,13) Details
TLR2 65(0,2,2,5) Details
interferon gamma 64(0,2,2,4) Details
TLR4 63(0,2,2,3) Details
NR2B 46(0,1,3,6) Details
lysozyme 44(0,1,2,9) Details
5 HT 1B 41(0,1,2,6) Details
interleukin 4 41(0,1,1,11) Details
interleukin (protein family or complex) 38(0,1,2,3) Details
P gp 38(0,1,2,3) Details
MX2 38(0,1,2,3) Details
tyrosine hydroxylase 35(0,1,1,5) Details
novel protein 34(0,1,1,4) Details
protein as 34(0,1,1,4) Details
cytochrome P450 (protein family or complex) 34(0,1,1,4) Details
histone deacetylase (protein family or complex) 33(0,1,1,3) Details
NR2A 33(0,1,1,3) Details
transferase 32(0,1,1,2) Details
K12 32(0,1,1,2) Details
CREB 2 32(0,1,1,2) Details
alkaline phosphatase 31(0,1,1,1) Details
caspase 9 31(0,1,1,1) Details
amine oxidases 31(0,1,1,1) Details
c Myc 31(0,1,1,1) Details
SP2 31(0,1,1,1) Details
c jun 31(0,1,1,1) Details
brains 53(0,0,6,23) Details
microRNAs 48(0,0,1,43) Details
c fos 44(0,0,1,39) Details
interleukin 1 beta 31(0,0,0,31) Details
HER2 30(0,0,1,25) Details
TP53 27(0,0,1,22) Details
Ki 67 26(0,0,2,16) Details
CD8 24(0,0,3,9) Details
immunoglobulin (protein family or complex) 22(0,0,0,22) Details
E cadherin 22(0,0,2,12) Details
muscles 20(0,0,2,10) Details
beta endorphin 19(0,0,1,14) Details
NR1 17(0,0,2,7) Details
SARS 17(0,0,0,17) Details
NTS1 17(0,0,0,17) Details
superoxide dismutase 16(0,0,2,6) Details
CD4 16(0,0,2,6) Details
MGMT 16(0,0,0,16) Details
ALDH2 16(0,0,2,6) Details
IL 6 16(0,0,1,11) Details
caspase 3 15(0,0,1,10) Details
protein is 15(0,0,2,5) Details
osteoclast differentiation factor 15(0,0,1,10) Details
RAI3 15(0,0,1,10) Details
bcl 2 15(0,0,1,10) Details
CYP2E1 14(0,0,2,4) Details
vimentin 14(0,0,1,9) Details
IL 8 14(0,0,0,14) Details
beta catenin 13(0,0,1,8) Details
PRNP 13(0,0,1,8) Details
ATPase 13(0,0,0,13) Details
progesterone receptors 13(0,0,1,8) Details
FOXO1 13(0,0,0,13) Details
ZO 1 13(0,0,1,8) Details
Substance P 12(0,0,0,12) Details
PS1 12(0,0,2,2) Details
cis 2 12(0,0,1,7) Details
hemoglobin (protein family or complex) 12(0,0,1,7) Details
p65 12(0,0,1,7) Details
glial fibrillary acidic protein 12(0,0,0,12) Details
vascular endothelial growth factor 11(0,0,0,11) Details
5 HT 6 11(0,0,0,11) Details
O GlcNAc 11(0,0,1,6) Details
KRAS 11(0,0,0,11) Details
CISH 11(0,0,1,6) Details
K ras 10(0,0,1,5) Details
cyclin D1 10(0,0,0,10) Details
GRP78 10(0,0,1,5) Details
p24 10(0,0,1,5) Details
CD31 10(0,0,0,10) Details
ARMS 10(0,0,0,10) Details
melanocortin 4 receptor 10(0,0,0,10) Details
p38 10(0,0,0,10) Details
calcitonin gene related peptide 10(0,0,0,10) Details
MUTYH 9(0,0,0,9) Details
protein PINCH 9(0,0,0,9) Details
CCL2 9(0,0,0,9) Details
PEG10 9(0,0,0,9) Details
endothelin 1 9(0,0,0,9) Details
nNOS 9(0,0,0,9) Details
NK1 9(0,0,1,4) Details
HEMA 9(0,0,1,4) Details
CD56 9(0,0,1,4) Details
hTERT 9(0,0,1,4) Details
CD117 8(0,0,1,3) Details
hormone receptors 8(0,0,1,3) Details
R12 8(0,0,1,3) Details
TRPM8 8(0,0,0,8) Details
ADH1 8(0,0,0,8) Details
ABH2 8(0,0,0,8) Details
caspase 12 8(0,0,1,3) Details
apolipoprotein E 8(0,0,1,3) Details
glutathione S transferases 8(0,0,1,3) Details
Mu opioid receptor 8(0,0,0,8) Details
estrogen receptor beta 7(0,0,0,7) Details
smooth muscle actin 7(0,0,1,2) Details
PARP 1 7(0,0,0,7) Details
desmin 7(0,0,1,2) Details
chemokines 7(0,0,0,7) Details
glyceraldehyde 3 phosphate dehydrogenase 7(0,0,0,7) Details
mitogen activated protein kinase (protein family or complex) 7(0,0,0,7) Details
cyclooxygenase 2 7(0,0,0,7) Details
occludin 7(0,0,1,2) Details
SS18 7(0,0,0,7) Details
CD11c 7(0,0,0,7) Details
CD62P 7(0,0,0,7) Details
PKCgamma 7(0,0,0,7) Details
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