Protein Information

Name glial fibrillary acidic protein
Synonyms GFAP; Glial fibrillary acidic protein; Glial fibrillary acidic proteins

Compound Information

Name formaldehyde
CAS formaldehyde

Reference List

PubMed Abstract RScore(About this table)
18288452 Turkmen N, Eren B, Fedakar R, Akgoz S, Comunoglu N: Glial fibrillary acidic protein (GFAP) and CD34 expression in the human optic nerve and brain in methanol toxicity. Adv Ther. 2008 Feb;25(2):123-32.

INTRODUCTION: The toxicity of methanol is as a result of its metabolites, formaldehyde and formic acid.
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17426605 Fu ES, Zhang YP, Sagen J, Yang ZQ, Bethea JR: Transgenic glial nuclear factor-kappa B inhibition decreases formalin pain in mice. Neuroreport. 2007 May 7;18(7):713-7.


In this work, we studied transgenic glial fibrillary acidic protein-IkappaBalpha-dn mice that selectively inactivate the classical nuclear factor kappaB pathway by overexpressing the inhibitory protein of kappaBalpha in astrocytes, under the control of glial fibrillary acidic protein promoter.
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19243685 Zhang J, Cheng H, Chen J, Yi F, Li W, Luan R, Guo W, Lv A, Rao Z, Wang H: Involvement of activated astrocyte and microglia of locus coeruleus in cardiac pain processing after acute cardiac injury. Neurol Res. 2009 May;31(4):432-8. Epub 2009 Feb 25.


Afterward, we analysed c-Fos, OX42, GFAP and P2X (4) R expression levels in the LC of the rats by immunofluorescence staining or Western blot analysis.
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17870246 Menetski J, Mistry S, Lu M, Mudgett JS, Ransohoff RM, Demartino JA, Macintyre DE, Abbadie C: Mice overexpressing chemokine ligand 2 (CCL2) in astrocytes display enhanced nociceptive responses. Neuroscience. 2007 Nov 9;149(3):706-14. Epub 2007 Aug 14.


In the present study, we assess nociceptive responses of mice that overexpressed CCL2 under control of glial fibrillary acidic protein promoter (CCL2 tg).
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