Protein Information

Name ADH1
Synonyms ADH 1; ADH1; ADH1A; Alcohol dehydrogenase 1; Alcohol dehydrogenase 1A; Alcohol dehydrogenase alpha subunit; Alcohol dehydrogenase 1s; Alcohol dehydrogenase 1As…

Compound Information

Name formaldehyde
CAS formaldehyde

Reference List

PubMed Abstract RScore(About this table)
19489444 Haseba T: [A new sight on alcohol metabolism and alcoholism--role of high Km alcohol dehydrogenase ADH3 (Class III)]. Nihon Arukoru Yakubutsu Igakkai Zasshi. 2009 Apr;44(2):78-93.


Alcohol metabolism is known to be mainly carried out by the classic ADH1 (Class I) of the liver.
7(0,0,0,7) Details
19376128 Shukla A, Durairaj G, Schneider J, Duan Z, Shadle T, Bhaumik SR: Stimulation of mRNA export by an F-box protein, Mdm30p, in vivo. J Mol Biol. 2009 Jun 5;389(2):238-47. Epub 2009 Apr 16.

With this view, we have systematically analyzed here the role of Mdm30p in regulation of transcriptional initiation, elongation, mRNA processing, and export in Saccharomyces cerevisiae, using a formaldehyde-based in vivo cross-linking and chromatin immunoprecipitation assay in conjunction with RT-PCR and fluorescence in situ hybridization.
We show that Mdm30p is dispensable for formation of the preinitiation complex assembly, association of elongating RNA polymerase II, and recruitment of mRNA capping enzyme, cap-binding complex, and 3' end formation machinery at the transcriptionally active genes such as ADH1, PHO84, and RPS5.
1(0,0,0,1) Details