| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | formaldehyde |
|---|---|
| CAS | formaldehyde |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19089010 | Li D, Wang Y, Yang C, Han K: Theoretical study of N-dealkylation of N-cyclopropyl-N-methylaniline catalyzed by cytochrome P450: insight into the origin of the regioselectivity. Dalton Trans. 2009 Jan 14;(2):291-7. Epub 2008 Nov 19. The first one is a Calpha-H hydroxylation on the N-substituent to form a carbinolaniline complex, and the second is a decomposition of the carbinolaniline to yield cyclopropanone (or formaldehyde) and N-methylaniline (or N-cyclopropylaniline). |
2(0,0,0,2) | Details |
| 17661096 | Liu X, Wang Y, Han K: Systematic study on the mechanism of oxidation to carboxylic acid by cytochrome P450. J Biol Inorg Chem. 2007 Sep;12(7):1073-81. Epub 2007 Jul 28. |
1(0,0,0,1) | Details |
| 18205321 | Cheng G, Wang M, Upadhyaya P, Villalta PW, Hecht SS: Formation of formaldehyde adducts in the reactions of DNA and deoxyribonucleosides with alpha-acetates of 4-(methylnitrosamino)-1-(3-pyridyl)-1- (NNK), 4-(methylnitrosamino)-1-(3-pyridyl)- (NNAL), and N-nitrosodimethylamine (NDMA). Chem Res Toxicol. 2008 Mar;21(3):746-51. Epub 2008 Jan 19. The cytochrome P450-mediated alpha-hydroxylation of the carcinogenic nitrosamines N-nitrosodimethylamine (NDMA, 1), 4-(methylnitrosamino)-1-(3-pyridyl)-1- (NNK, 6a), and 4-(methylnitrosamino)-1-(3-pyridyl)- (NNAL, 6b) produces diazonium ions and formaldehyde. |
31(0,1,1,1) | Details |