Name | interleukin 4 |
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Synonyms | B cell differentiation factor gamma; B cell growth factor; B cell stimulatory factor 1; BCDF gamma; BCDFg; BCDFgamma; BCGF; BSF 1… |
Name | formaldehyde |
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CAS | formaldehyde |
PubMed | Abstract | RScore(About this table) | |
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19422874 | De Jong WH, Arts JH, De Klerk A, Schijf MA, Ezendam J, Kuper CF, Van Loveren H: Contact and respiratory sensitizers can be identified by cytokine profiles following inhalation exposure. Toxicology. 2009 Jul 10;261(3):103-11. Epub 2009 May 5. After inhalation exposure the respiratory sensitizers induced more interleukin-4 (IL-4) and interleukin (IL-10) compared to the contact sensitizers, whereas the contact sensitizers, except formaldehyde, induced relatively more interferon-gamma (IFN-gamma) production. |
32(0,1,1,2) | Details |
19042193 | Tarkowski M, Kur B, Polakowska E, Jablonska E: Comparative studies of lymph node cell subpopulations and cytokine expression in murine model for testing the potentials of chemicals to induce respiratory sensitization. Int J Occup Med Environ Health. 2008;21(3):253-62. MATERIALS AND METHODS: On day 1 and 7, Balb/c mice received toluene-2,4-diisocyanate (TDI), trimellitic anhydride (TMA), 1-chloro-2,4-dinitrobenzene (DNCB), glutaraldehyde (GA), formaldehyde (FA), benzalkonium (ChB) or vehicle. On day 15, auricular lymph nodes (LN) were excised and used for analyzes of T-, B-cells, expression of CD44 and for the estimation of IL-4 and IFN-gamma production after in vitro stimulation with concanavalin A (ConA) and also for IL-4 and IFN-gamma mRNA expression analyses using Real-Time PCR. |
3(0,0,0,3) | Details |
17979570 | Schiltz PM, Lee GJ, Zhang JG, Hoa N, Wepsic HT, Dillman RO, Jadus MR: Human allogeneic and murine xenogeneic dendritic cells are cytotoxic to human tumor cells via two distinct pathways. Cancer Biother Radiopharm. 2007 Oct;22(5):672-83. Human monocyte-derived dendritic cells (DCs), stimulated with granulocyte-macrophage colony-stimulating factor and interleukin-4 for 1 week, major histocompatibility complex killed human tumor cells in 24-hour cytotoxicity assays. |
1(0,0,0,1) | Details |
19827972 | Qiao Y, Li B, Yang G, Yao H, Yang J, Liu D, Yan Y, Sigsgaard T, Yang X: Irritant and adjuvant effects of gaseous formaldehyde on the ovalbumin-induced hyperresponsiveness and inflammation in a rat model. Inhal Toxicol. 2009 Oct 14. Results: The airway reactivity, lung histological changes, pulmonary interleukin-4 secretion, and eosinophil infiltration in the OVA and FA exposed rats were significantly higher after gaseous FA exposures of 417 and 2500 ppb. |
1(0,0,0,1) | Details |
19904815 | Saito A, Tanaka H, Usuda H, Shibata T, Higashi S, Yamashita H, Inagaki N, Nagai H: Characterization of skin inflammation induced by repeated exposure of toluene, xylene, and formaldehyde in mice. Environ Toxicol. 2009 Nov 10. In addition, FA exposure markedly increased the expression of interleukin-4 (IL-4), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and transient receptor potential vanilloid-1 (TRPV-1) mRNAs in the ears and IL-4 and NT-3 mRNAs in the cervical lymph nodes. |
1(0,0,0,1) | Details |
19542471 | Percopo CM, Qiu Z, Phipps S, Foster PS, Domachowske JB, Rosenberg HF: Pulmonary eosinophils and their role in immunopathologic responses to formalin-inactivated pneumonia virus of mice. J Immunol. 2009 Jul 1;183(1):604-12. However, levels of both IL-4 and CCL3 (macrophage inflammatory protein-1alpha) in bronchoalveolar lavage fluid were markedly diminished in PVM Ag-vaccinated, PVM-infected eosinophil-deficient mice when compared with wild-type controls. |
1(0,0,0,1) | Details |
17515642 | Tsunetsugu-Yokota Y, Ato M, Takahashi Y, Hashimoto S, Kaji T, Kuraoka M, Yamamoto K, Mitsuki YY, Yamamoto T, Oshima M, Ohnishi K, Takemori T: Formalin-treated UV-inactivated SARS coronavirus vaccine retains its immunogenicity and promotes Th2-type immune responses. Jpn J Infect Dis. 2007 May;60(2-3):106-12. Interestingly, the UV-F-V vaccine induced fewer IgG (2a) subtype antibodies and higher interleukin-4 production in vaccinated mice than did UV-V. |
1(0,0,0,1) | Details |
17570926 | Gisch K, Gehrke N, Bros M, Priesmeyer C, Knop J, Reske-Kunz AB, Sudowe S: Formalin-fixed Staphylococcus aureus particles prevent allergic sensitization in a murine model of type I allergy. Int Arch Allergy Immunol. 2007;144(3):183-96. Epub 2007 Jun 15. RESULTS: Simultaneous application of OVA and Staphylococcus particles very efficiently inhibited production of specific IgE and IgG1 as well as secretion of IL-4 and IL-5 by splenocytes, while enhancing IgG2a formation and production of IFN-gamma, indicating a shift from a Th2 response towards a Th1-biased response. |
1(0,0,0,1) | Details |