Protein Information

Name interferon gamma
Synonyms IFG; IFI; IFN gamma; IFNG; IFNgamma; Immune interferon; Interferon gamma; Interferon gamma precursor…

Compound Information

Name formaldehyde
CAS formaldehyde

Reference List

PubMed Abstract RScore(About this table)
18849615 Sasaki Y, Ohtani T, Ito Y, Mizuashi M, Nakagawa S, Furukawa T, Horii A, Aiba S: Molecular events in human T cells treated with diesel exhaust particles or formaldehyde that underlie their diminished interferon-gamma and interleukin-10 production. Int Arch Allergy Immunol. 2009;148(3):239-50. Epub 2008 Oct 10.
32(0,1,1,2) Details
19422874 De Jong WH, Arts JH, De Klerk A, Schijf MA, Ezendam J, Kuper CF, Van Loveren H: Contact and respiratory sensitizers can be identified by cytokine profiles following inhalation exposure. Toxicology. 2009 Jul 10;261(3):103-11. Epub 2009 May 5.

After inhalation exposure the respiratory sensitizers induced more interleukin-4 (IL-4) and interleukin (IL-10) compared to the contact sensitizers, whereas the contact sensitizers, except formaldehyde, induced relatively more interferon-gamma (IFN-gamma) production.
31(0,1,1,1) Details
18243933 Gerner W, Kaser T, Pintaric M, Groiss S, Saalmuller A: Detection of intracellular antigens in porcine PBMC by flow cytometry: A comparison of fixation and permeabilisation reagents. Vet Immunol Immunopathol. 2008 Feb 15;121(3-4):251-9. Epub 2007 Oct 2.

In order to improve information about suitable fixation/permeabilisation protocols in porcine lymphocytes we tested six fixation/permeabilisation variants for the staining of different intracellular antigens: CD79alpha, perforin, interferon-gamma and the cell cycle associated protein Ki-67.
For the fixation/permeabilisation procedure, four commercial kits from BD Biosciences, ADG Bio Research, Dako and AbD Serotec were tested in comparison to non-commercial fixation solutions of formaldehyde together with either saponin or Tween-20 for permeabilisation.
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19827972 Qiao Y, Li B, Yang G, Yao H, Yang J, Liu D, Yan Y, Sigsgaard T, Yang X: Irritant and adjuvant effects of gaseous formaldehyde on the ovalbumin-induced hyperresponsiveness and inflammation in a rat model. Inhal Toxicol. 2009 Oct 14.

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17673148 Gao S, Liu C, Qu S, Song J, Li J, Zhang P, Wang Q, Guo C, Gao F, Zhang L: Non-cell Corynebacterium parvum generated by nanotechnology: a promising immunomodulator with less side effects. Int Immunopharmacol. 2007 Oct;7(10):1334-42. Epub 2007 Jun 19.


In present study, we compared effect of NCPP with that of CP and found: (1) NCPP with non-formaldehyde residue was easy to be absorbed without swelling and scleroma in local injected areas; (2) NCPP caused no obvious liver injury in murine and macaques; (3) NCPP maintained powerful anti-tumor activity, increased splenic index, elevated macrophage number, phagocytosis and production of hydrogen peroxide (H (2) O (2)), and nitric oxide (NO); (4) Importantly, unparallel CP, NCPP could stimulate macrophages to produce low level of tumor necrosis factor-alpha (TNF-alpha) but high level of interferon-gamma (IFN-gamma), an inhibitor to fibrosis.
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