Protein Information

Name osteoclast differentiation factor
Synonyms CD254; ODF; SODF; CD254 antigen; OPGL; Osteoclast differentiation factor; Osteoprotegerin ligand; RANKL…

Compound Information

Name formaldehyde
CAS formaldehyde

Reference List

PubMed Abstract RScore(About this table)
19370270 Haghighi M: Formaldehyde cross-linking of proteins to osteoclast differentiation factor promoter for the identification of biofunctional proteins. Saudi Med J. 2009 Apr;30(4):472-7.
7(0,0,1,2) Details
19249596 Huang FM, Lee SS, Yang SF, Chang YC: Up-regulation of receptor activator nuclear factor-kappaB ligand expression by root canal sealers in human osteoblastic cells. J Endod. 2009 Mar;35(3):363-6.


A recently identified tumor necrosis factor family molecule, receptor activator of nuclear factor-kappaB ligand (RANKL), plays a critical role in the development of osteoclasts that result in bone resorption.
6(0,0,0,6) Details
18486789 Queiroz TP, Souza FA, Okamoto R, Margonar R, Pereira-Filho VA, Garcia Junior IR, Vieira EH: Evaluation of immediate bone-cell viability and of drill wear after implant osteotomies: immunohistochemistry and scanning electron microscopy analysis. J Oral Maxillofac Surg. 2008 Jun;66(6):1233-40.

The animals were euthanized immediately after the osteotomies by perfusion with 4% formaldehyde.
Samples then underwent immunohistochemistry processing for ordinal qualitative analysis of osteoprotegerin (OPG), the RANK ligant (RANKL; a tumor-related necrosis factor receptor family), and osteocalcin protein immunolabels, as detected by the immunoperoxidase method and revealed with 3,3-diaminobenzidine.
2(0,0,0,2) Details