Protein Information

Name 5 HT 6
Synonyms 5 hydroxytryptamine receptor 6; serotonin receptor; 5 HT 6; 5 HT6; 5 hydroxytryptamine (serotonin) receptor 6; 5 hydroxytryptamine 6 receptor; HTR 6; HTR6…

Compound Information

Name formaldehyde
CAS formaldehyde

Reference List

PubMed Abstract RScore(About this table)
19422883 Castaneda-Corral G, Rocha-Gonzalez HI, Araiza-Saldana CI, Ambriz-Tututi M, Vidal-Cantu GC, Granados-Soto V: Role of peripheral and spinal 5-HT6 receptors according to the rat formalin test. Neuroscience. 2009 Aug 18;162(2):444-52. Epub 2009 May 5.

6(0,0,0,6) Details
17599826 Finn DP, Fone KC, Beckett SR, Baxter JA, Ansell L, Marsden CA, Chapman V: The effects of pharmacological blockade of the 5-HT (6) receptor on formalin-evoked nociceptive behaviour, locomotor activity and hypothalamo-pituitary-adrenal axis activity in rats. Eur J Pharmacol. 2007 Aug 13;569(1-2):59-63. Epub 2007 Jun 5.

4(0,0,0,4) Details
18723285 Nikai T, Basbaum AI, Ahn AH: Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan. Pain. 2008 Oct 31;139(3):533-40. Epub 2008 Aug 23.


Sumatriptan and the other triptan drugs target the serotonin receptor subtypes1B, 1D, and 1F (5-HT (1B/D/F)), and are prescribed widely in the treatment of migraine.
1(0,0,0,1) Details