Protein Information

Name ATPase
Synonyms ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1…

Compound Information

Name formaldehyde
CAS formaldehyde

Reference List

PubMed Abstract RScore(About this table)
18708502 Stone CB, Johnson DL, Bulir DC, Gilchrist JD, Mahony JB: Characterization of the putative type III secretion ATPase CdsN (Cpn0707) of Chlamydophila pneumoniae. J Bacteriol. 2008 Oct;190(20):6580-8. Epub 2008 Aug 15.

CdsN formed oligomers and high-molecular-weight multimers, as assessed by formaldehyde fixation and nondenaturing polyacrylamide gel electrophoresis.
4(0,0,0,4) Details
19246765 Karst JC, Foucher AE, Campbell TL, Di Guilmi AM, Stroebel D, Mangat CS, Brown ED, Jault JM: The ATPase activity of an 'essential' Bacillus subtilis enzyme, YdiB, is required for its cellular function and is modulated by oligomerization. Microbiology. 2009 Mar;155(Pt 3):944-56.

Importantly, dimers of YdiB were also observed in a B. subtilis extract, or when stabilized by formaldehyde cross-linking for YjeE from E. coli, suggesting that oligomerization might regulate the function of this new class of proteins in vivo.
4(0,0,0,4) Details
17550236 Faouzi S, Medzihradszky KF, Hefner C, Maher JJ, Correia MA: Characterization of the physiological turnover of native and inactivated cytochromes P450 3A in cultured rat hepatocytes: a role for the cytosolic AAA ATPase p97?. Biochemistry. 2007 Jul 3;46(26):7793-803. Epub 2007 Jun 6.

2(0,0,0,2) Details
18247558 Stauber J, Lemaire R, Franck J, Bonnel D, Croix D, Day R, Wisztorski M, Fournier I, Salzet M: MALDI imaging of formalin-fixed paraffin-embedded tissues: application to model animals of Parkinson disease for biomarker hunting. J Proteome Res. 2008 Mar;7(3):969-78. Epub 2008 Feb 5.


In contrast, peroxidoredoxin 6, F1 ATPase, and alpha-enolase are up-regulated.
1(0,0,0,1) Details
19128014 Balgley BM, Guo T, Zhao K, Fang X, Tavassoli FA, Lee CS: Evaluation of archival time on shotgun proteomics of formalin-fixed and paraffin-embedded tissues. J Proteome Res. 2009 Feb;8(2):917-25.


Vacuolar proton translocating ATPase 116 kDa subunit isoform a3, one of the unique proteins expressed in the ASPS, is further validated by immunohistochemistry (IHC).
1(0,0,0,1) Details
18827478 O'Malley JT, Merchant SN, Burgess BJ, Jones DD, Adams JC: Effects of fixative and embedding medium on morphology and immunostaining of the cochlea. Audiol Neurootol. 2009;14(2):78-87. Epub 2008 Oct 1.

Three different fixative solutions [4% formaldehyde (F), 4% formaldehyde + 1% acetic acid (FA), and 4% formaldehyde + 1% acetic acid + 0.1% glutaraldehyde (FGA)] and 3 different embedding media (paraffin, polyester wax, and celloidin) were used.
Immunostaining was studied using a panel of 6 antibodies (to prostaglandin D synthase, aquaporin 1, connective tissue growth factor, 200-kDa neurofilament, tubulin and Na (+),K (+)-ATPase).
1(0,0,0,1) Details