Protein Information

Name vimentin
Synonyms VIM; Vimentin; Vimentins

Compound Information

Name formaldehyde
CAS formaldehyde

Reference List

PubMed Abstract RScore(About this table)
18410440 Rogerson L, Darby S, Jabbar T, Mathers ME, Leung HY, Robson CN, Sahadevan K, O'Toole K, Gnanapragasam VJ: Application of transcript profiling in formalin-fixed paraffin-embedded diagnostic prostate cancer needle biopsies. BJU Int. 2008 Aug;102(3):364-70. Epub 2008 Apr 11.


RESULTS: LCM and RNA extraction was achieved in all biopsies from a pilot cohort of five patients. cDNA produced was successfully used to detect expression of glyceraldehyde-3-phosphate dehydrogenase, RPL13, prostate-specific antigen, vimentin, inhibitor of differentiation/DNA binding 1 (Id-1) and polycomb group protein enhancer of zeste homolog 2 (EZH2) transcripts.
1(0,0,0,1) Details
18060198 Petrescu A, Berdan G, Hulea I, Gaitanidis R, Ambert V, Jinga V, Popescu M, Andrei F, Niculescu L: Renal inflammatory myofibroblastic tumor - a new case report. Rom J Morphol Embryol. 2007;48(4):437-42.

Fragments of the tumor were fixed in 10% formaldehyde, included in paraffin, and the sections were stained with HE, VG and immunohistochemically with vimentin (VIM), MNF116, SyN, smooth muscle actin (ACT), desmin, CD68, S100, HMB45, and CD117.
6(0,0,1,1) Details
18307046 Hipp S, Walch A, Schuster T, Hofler H, Becker KF: Precise measurement of the E-cadherin repressor Snail in formalin-fixed endometrial carcinoma using protein lysate microarrays. Clin Exp Metastasis. 2008;25(6):679-83. Epub 2008 Feb 29.


Over-expression of the zinc finger transcription factor Snail leads to down-regulation of the epithelial proteins E-cadherin and Cytokeratin 18 and to upregulation of the mesenchymal protein Vimentin.
2(0,0,0,2) Details
17552912 Jarutat T, Nickels C, Frisch C, Stellmacher F, Hofig KP, Knappik A, Merz H: Selection of vimentin-specific antibodies from the HuCAL phage display library by subtractive panning on formalin-fixed, paraffin-embedded tissue. Biol Chem. 2007 Jun;388(6):651-8.

2(0,0,0,2) Details
19888862 Lassalle S, Hofman V, Marius I, Gavric-Tanga V, Brest P, Havet K, Butori C, Selva E, Santini J, Mograbi B, Hofman P: Assessment of morphology, antigenicity, and nucleic acid integrity for diagnostic thyroid pathology using formalin substitute fixatives. Thyroid. 2009 Nov;19(11):1239-48.

BACKGROUND: With the advent of the formaldehyde standard law in France, and because of the impact of new methods for diagnosis and prognosis in pathology, formalin replacement in surgical pathology laboratories is currently being discussed in France.
Tissues were stained (hematoxylin-eosin, periodic acid Schiff, trichromic Masson, and Sweet-Gordon staining) and their antigenicity determined by immunohistochemistry (performed with HBME-1, galectin-3, CK19, vimentin, CD31, and KL1 antibodies).
1(0,0,0,1) Details
19902233 Witter K, Tonar Z, Matejka VM, Martinca T, Jonak M, Rokosny S, Pirk J: Tissue reaction to three different types of tissue glues in an experimental aorta dissection model: a quantitative approach. Histochem Cell Biol. 2009 Nov 10.

The aim of our study was to use a porcine experimental model of infrarenal aorta dissection to compare histological changes of the vessel wall 1, 6 and 12 months after application of BioGlue, Gelatin-resorcin-formaldehyde (GRF) glue and Tissucol.
In GRF samples, actin, desmin and vimentin expression changed most severely.
1(0,0,0,1) Details
19242828 Kjaer I, Nolting D: The human periodontal membrane: focusing on the spatial interrelation between the epithelial layer of Malassez, fibers, and innervation. Acta Odontol Scand. 2009;67(3):134-8.

The extracted teeth, fixed in 4% neutral buffered formaldehyde for 5 days, were decalcified in 0.5 M EDTA.
Immunohistochemical reactions: Cytokeratin (wide spectrum screening) for epithelium, anti-vimentin for fibers, and anti-neuronal nuclei (NeuN) for innervation.
1(0,0,0,1) Details