| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | imazalil |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9460227 | Muto N, Hirai H, Tanaka T, Itoh N, Tanaka K: Induction and inhibition of cytochrome P450 isoforms by imazalil, a food contaminant, in mouse small intestine and liver. Xenobiotica. 1997 Dec;27(12):1215-23. |
249(3,3,4,4) | Details |
| 2561184 | Vanden Bossche H, Marichal P, Gorrens J, Coene MC, Willemsens G, Bellens D, Roels I, Moereels H, Janssen PA: Biochemical approaches to selective antifungal activity. Mycoses. 1989;32 Suppl 1:35-52. Azole antifungals (e.g. the imidazoles: miconazole, bifonazole, imazalil, ketoconazole, and the triazoles: diniconazole, triadimenol, propiconazole, fluconazole and itraconazole) inhibit in fungal cells the 14 alpha-demethylation of or 24-methylenedihydrolanosterol. The consequent inhibition of synthesis originates from binding of the unsubstituted (N-3 or N-4) of their or triazole moiety to the heme iron and from binding of their N-1 substituent to the apoprotein of a cytochrome P-450 (P-450 (14) DM) of the endoplasmic reticulum. |
1(0,0,0,1) | Details |
| 17084873 | Takeuchi S, Matsuda T, Kobayashi S, Takahashi T, Kojima H: In vitro screening of 200 pesticides for agonistic activity via mouse peroxisome proliferator-activated receptor (PPAR) alpha and PPARgamma and quantitative analysis of in vivo induction pathway. Toxicol Appl Pharmacol. 2006 Dec 15;217(3):235-44. Epub 2006 Sep 6. To investigate the in vivo effects of diclofop-methyl, pyrethrins and imazalil, we examined the gene expression of PPARalpha-inducible cytochrome P450 4As (CYP4As) in the liver of female mice intraperitoneally injected with these compounds (< or =300 mg/kg). |
6(0,0,1,1) | Details |
| 3386231 | Drummond TD, Mason JI, McCarthy JL: Gerbil 11 beta- and 19-hydroxylating activities respond similarly to inhibitory or stimulatory agents: two activities of a single enzyme. J Steroid Biochem. 1988 Jun;29(6):641-8. Inhibitors of steroidogenesis and a polyclonal antibody against bovine cytochrome P-450 (11 beta) were used to determine if the agents would effect differential or parallel suppression of 19- vs 11 beta-hydroxylation by gerbil mitochondria in vitro. The inhibitors (0.1-60 microM) tested (listed in order of decreasing effectiveness) were imazalil, miconazole and 4-hydroxyandrostenedione. |
1(0,0,0,1) | Details |