Name | statins |
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Synonyms | STN; statin; statins |
Name | TCA |
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CAS | 2,2,2-trichloroacetic acid |
PubMed | Abstract | RScore(About this table) | |
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16232003 | Landsman PB, Yu W, Liu X, Teutsch SM, Berger ML: Impact of 3-tier pharmacy benefit design and increased consumer cost-sharing on drug utilization. Am J Manag Care. 2005 Oct;11(10):621-8. Switches to lower copayments for ACE inhibitors, statins, and triptans occurred more often for cases. |
2(0,0,0,2) | Details |
15901796 | Hirano M, Maeda K, Hayashi H, Kusuhara H, Sugiyama Y: Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, J Pharmacol Exp Ther. 2005 Aug;314(2):876-82. Epub 2005 May 18. The inhibitory effects of hydrophilic statins and rosuvastatin) on the uptake of TCA by BSEP were relatively lower than those of lipophilic statins. |
1(0,0,0,1) | Details |
19175937 | Knight LA, Kurbacher CM, Glaysher S, Fernando A, Reichelt R, Dexel S, Reinhold U, Cree IA: Activity of mevalonate pathway inhibitors against breast and ovarian cancers in the ATP-based tumour chemosensitivity assay. BMC Cancer. 2009 Jan 28;9:38. Previous data suggest that lipophilic statins such as fluvastatin and N-bisphosphonates such as zoledronic acid, both inhibitors of the metabolic pathway, have anti-cancer effects in vitro and in patients. |
1(0,0,0,1) | Details |