Name | superoxide dismutase |
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Synonyms | IPO B; Indophenoloxidase B; MNSOD; Manganese superoxide dismutase; Manganese containing superoxide dismutase; Mangano superoxide dismutase; Mn superoxide dismutase; Mn SOD… |
Name | copper sulfate |
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CAS | sulfuric acid copper(2+) salt (1:1) |
PubMed | Abstract | RScore(About this table) | |
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9199613 | Mattsson C, Marklund SL, Hellstrom S: Application of The results showed that treatment with zinc-superoxide dismutase plus catalase and deferoxamine inhibited or reduced the development of myringosclerosis, whereas the ears treated with copper sulfate plus iron appeared unaffected. |
free radical scavengers to diminish the occurrence of myringosclerosis. Ann Otol Rhinol Laryngol. 1997 Jun;106(6):513-8.37(0,1,2,2) | Details |
11470327 | Alcaraz-Zubeldia M, Montes S, Rios C: Participation of manganese-superoxide dismutase in the neuroprotection exerted by copper sulfate against 1-methyl 4-phenylpyridinium neurotoxicity. Brain Res Bull. 2001 May 15;55(2):277-9. |
10(0,0,1,5) | Details |
2820500 | Huber KR, Sridhar R, Griffith EH, Amma EL, Roberts J: Superoxide dismutase-like activities of (II) complexes tested in serum. Biochim Biophys Acta. 1987 Sep 24;915(2):267-76. |
6(0,0,0,6) | Details |
16828944 | Wu ZX, Gan NQ, Huang Q, Song LR: Response of microcystis to Upon exposure to 0.25 mgl (-1) copper sulfate, the activities of antioxidative enzyme, such as superoxide dismutase (SOD) and catalase (CAT), were significantly increased in colonial Microcystis compared to unicellular Microcystis. |
stress: do phenotypes of microcystis make a difference in stress tolerance?. Environ Pollut. 2007 May;147(2):324-30. Epub 2006 Jul 7.6(0,0,1,1) | Details |
14556383 | Jouili H, el Ferjani E: Changes in antioxidant and lignifying enzyme activities in sunflower roots (Helianthus annuus L.) stressed with SOD (superoxide dismutase, EC 1.15.1.1) activity was reduced but CAT (catalase, EC 1.11.1.6) and GPX peroxidase, EC 1.11.1.7) activities were significantly enhanced. |
excess. C R Biol. 2003 Jul;326(7):639-44.1(0,0,0,1) | Details |
8400082 | Keane WF, O'Donnell MP, Kasiske BL, Kim Y: Oxidative modification of low-density lipoproteins by mesangial cells. J Am Soc Nephrol. 1993 Aug;4(2):187-94. This peroxidation of LDL involved because superoxide dismutase and butylated hydroxytoluene prevented it, whereas scavengers were without effect. Native LDL subjected to chemical oxidation by copper sulfate also inhibited mesangial cell proliferation. |
1(0,0,0,1) | Details |
1554379 | Pelletier O, Hill I, Birnboim HC: Inhibition by superoxide dismutase-mimetic complexes of phorbol ester-induced respiratory burst in human granulocytes. Biochem Pharmacol. 1992 Mar 3;43(5):1061-6. Similar inhibitory effects were seen using copper sulfate. |
2(0,0,0,2) | Details |
8485631 | Berman RS, Martin W: Arterial endothelial barrier dysfunction: actions of xanthine oxidase free radical generating system. Br J Pharmacol. 1993 Apr;108(4):920-6. The increase in albumin transfer induced by and xanthine oxidase was abolished by catalase (3 u ml-1), reduced by allopurinol (4 mM), but unaffected by superoxide dismutase (6000 u ml-1), the scavengers, (15 mM), dimethylthiourea (10 mM) and N-(2-mercaptopropionyl)- (1 mM), the iron chelator, deferoxamine (0.5 mM), ferric (50 microM), an inhibitor of synthase, NG-nitro- (30 microM), or the antioxidant, (3 mM). 4. |
and the -2(0,0,0,2) | Details |
1953187 | Lenskaia EG, Tazhibaev ShS, Karsybekova NM, Alekseeva NR, Sarbaev VT: [Alimentary methods of maintaining the superoxide dismutase activity in the tissues of rats during growth of a transplanted tumor and administration of carminomycin]. Antibiot Khimioter. 1991 Jul;36(7):32-4. |
2(0,0,0,2) | Details |
3435476 | Dameron CT, Harris ED: Regulation of aortic CuZn-superoxide dismutase with Biochem J. 1987 Dec 15;248(3):663-8. |
2(0,0,0,2) | Details |
9016830 | Ossola JO, Groppa MD, Tomaro ML: Relationship between oxidative stress and heme oxygenase induction by copper sulfate. Arch Biochem Biophys. 1997 Jan 15;337(2):332-7. To evaluate liver antioxidant enzymatic defenses, superoxide dismutase, catalase, and peroxidase activities were determined. |
2(0,0,0,2) | Details |
8213346 | Sordelli DO, Fontan PA, Amura CR: Piroxicam- complexes: inhibition of polymorphonuclear leukocyte migration to Pseudomonas aeruginosa chemotactins in vivo and superoxide dismutase-like activity in vitro. Agents Actions. 1993 Mar;38(3-4):196-201. |
2(0,0,0,2) | Details |
8639607 | Schultz JR, Ellerby LM, Gralla EB, Valentine JS, Clarke CF: Autoxidation of superoxide dismutase. . Biochemistry. 1996 May 28;35(21):6595-603. |
-6 is independent of 2(0,0,0,2) | Details |
1649087 | Kohen R, Misgav R, Ginsburg I: The SOD like activity of copper:carnosine, copper:anserine and copper:homocarnosine complexes. Free Radic Res Commun. 1991;12-13 Pt 1:179-85. We have studied the ability of the copper:carnosine (and other derivatives) complexes to act as superoxide dismutase. |
2(0,0,0,2) | Details |
2774578 | DiSilvestro RA: activation of superoxide dismutase in rat erythrocytes. . Arch Biochem Biophys. 1989 Oct;274(1):298-303. |
2(0,0,0,2) | Details |
12899943 | Santamaria A, Flores-Escartin A, Martinez JC, Osorio L, Galvan-Arzate S, Pedraza-Chaverri J, Maldonado PD, Medina-Campos ON, Jimenez-Capdeville ME, Manjarrez J, Rios C: blocks neurotoxicity in rats: contribution of antioxidant systems. Free Radic Biol Med. 2003 Aug 15;35(4):418-27. In addition, reduced the QUIN-induced decreased striatal activity of Cu,Zn-dependent superoxide dismutase, and increased the ferroxidase activity of ceruloplasmin in cerebrospinal fluid from QUIN-treated rats. |
1(0,0,0,1) | Details |
14513838 | Lombardo MF, Ciriolo MR, Rotilio G, Rossi L: Prolonged triggers apoptosis in SH-SY5Y neuroblastoma cells. Cell Mol Life Sci. 2003 Aug;60(8):1733-43. Mitochondrial antioxidants (Mn superoxide dismutase and Bcl-2) were up-regulated. The addition of copper sulfate to the -depleted cells restored enzymes, normalized antioxidant levels and improved cell viability. |
depletion induces expression of antioxidants and 1(0,0,0,1) | Details |
3934352 | Uauy R, Castillo-Duran C, Fisberg M, Fernandez N, Valenzuela A: Red cell superoxide dismutase activity as an index of human nutrition. J Nutr. 1985 Dec;115(12):1650-5. Nine served as controls receiving a copper sulfate supplement (80 micrograms/kg daily for 120 d; eight received a placebo and were supplemented only if plasma levels dropped below 90 micrograms/dl or on d 90 for at least 30 d. |
2(0,0,0,2) | Details |
3094197 | Wallace KB: Nonenzymatic activation and stimulation of lipid peroxidation by doxorubicin- Toxicol Appl Pharmacol. 1986 Oct;86(1):69-79. Associated with these changes was a -dependent consumption of dissolved and a superoxide dismutase-sensitive reduction of ferricytochrome c, suggesting the liberation of free radicals. |
2(0,0,0,2) | Details |
15340235 | Fukaya Y, Yamaguchi M: Regucalcin increases superoxide dismutase activity in rat liver cytosol. . Biol Pharm Bull. 2004 Sep;27(9):1444-6. |
2(0,0,0,2) | Details |
12832419 | Bertinato J, L'Abbe MR: modulates the degradation of chaperone for Cu,Zn superoxide dismutase by the 26 S proteosome. J Biol Chem. 2003 Sep 12;278(37):35071-8. Epub 2003 Jun 27. |
2(0,0,0,2) | Details |
10416023 | Schultz JR, Clarke CF: Characterization of Saccharomyces cerevisiae Superoxide dismutase (SOD) activity decreased and catalase activity increased in both Q-deficient and atp2 delta mutants compared to wild-type cells, suggesting that such changes result from the loss of respiration rather than the lack of Q. |
-deficient mutants. Biofactors. 1999;9(2-4):121-9.1(0,0,0,1) | Details |
18021535 | Wan XH, Li YW, Luo XP: liver injury in -overloaded rats]. Zhonghua Er Ke Za Zhi. 2007 Aug;45(8):604-8. Malondialdehyde (MDA), superoxide dismutase (SOD) and (GSH) in liver homogenates were measured to reflect the induced lipid peroxidation. -overloaded rat model was established by feeding with forage containing 1 g/kg copper sulfate and water with 0.185% copper sulfate for 8 weeks or 12 weeks. |
attenuated the lipid peroxidation and apoptotic 1(0,0,0,1) | Details |
16023296 | Gupta SC, Siddique HR, Saxena DK, Chowdhuri DK: Hazardous effect of organophosphate compound, dichlorvos in transgenic Drosophila melanogaster (hsp70-lacZ): induction of hsp70, anti-oxidant enzymes and inhibition of acetylcholinesterase. Biochim Biophys Acta. 2005 Aug 30;1725(1):81-92. Third instar larvae of Drosophila melanogaster transgenic for hsp70 were exposed to 0.1 to 100.0 ppb dichlorvos and 5.0 mM CuSO (4) (an inducer of oxidative stress and stress genes) and hsp70, and activities of acetylcholinesterase (AchE), superoxide dismutase (SOD), catalase (CAT) and lipid peroxidation (LPO) product were measured. |
1(0,0,0,1) | Details |
17703862 | Hseu YC, Chang WH, Chen CS, Liao JW, Huang CJ, Lu FJ, Chia YC, Hsu HK, Wu JJ, Yang HL: Antioxidant activities of Toona Sinensis leaves extracts using different antioxidant models. Food Chem Toxicol. 2008 Jan;46(1):105-14. Epub 2007 Jul 16. Furthermore, AAPH-induced oxidative hemolysis, lipid peroxidation, and decline in superoxide dismutase (SOD) activity in human erythrocytes were prevented by both the TS extracts and the |
1(0,0,0,1) | Details |
12768346 | Raeymaekers T, Potters G, Asard H, Guisez Y, Horemans N: mediated oxidative burst in Nicotiana tabacum L. cv. Protoplasma. 2003 May;221(1-2):93-100. Superoxide dismutase (5 U/ml) induced an increase in H (2) O (2) production by 22.2%. |
-1(0,0,0,1) | Details |
3784221 | Asano R, Hokari S: Hemolysis of bovine erythrocytes induced by and its relationship to superoxide dismutase activity. Nippon Juigaku Zasshi. 1986 Oct;48(5):887-91. |
1(0,0,0,1) | Details |
15303382 | Kvietkauskaite R, Dringeliene A, Markevicius A, Siaurys A, Acaite J: Effect of low Low-level excess was produced in male BALB/c mice by oral supplementation of copper sulfate solution during a 19-w period. Chronic copper impaired the liver antioxidant defense system by decreasing activities of Cu,Zn-superoxide dismutase and catalase to 14% and 11% respectively. |
exposure on the antioxidant system and some immune parameters. Vet Hum Toxicol. 2004 Aug;46(4):169-72.1(0,0,0,1) | Details |
12512603 | Yost GP, Arthington JD, McDowell LR, Martin FG, Wilkinson NS, Swenson CK: Effect of Red blood cell superoxide dismutase (SOD) activity was higher (P < 0.001) in heifers receiving CuSO4 than Availa-Cu (0.98 vs 0.87 U). |
source and level on the rate and extent of repletion in Holstein heifers. J Dairy Sci. 2002 Dec;85(12):3297-303.1(0,0,0,1) | Details |
3673601 | Dimitrova D, Radonova N, Ivancheva E, Russanov E: The hemolytic effect of complexes with different ligands. . Acta Physiol Pharmacol Bulg. 1987;13(2):48-53. The hemolysis greatly decreased in the presence of chelator of Cu (I) and superoxide dismutase, which suggested oxi-reduction transitions and participation of in the process. |
1(0,0,0,1) | Details |
19523602 | Upadhyay RK, Panda SK: inhibition, oxidative stress and ultrastructural alterations in freshly grown water lettuce (Pistia stratiotes L.). C R Biol. 2009 Jul;332(7):623-32. Epub 2009 Apr 29. The effects of increasing concentrations of on the growth, ultra-structure and on certain biochemical parameters of water lettuce (Pistia stratiotes L.) were investigated under controlled conditions in the nutrient solutions containing increased copper sulfate concentrations ranging from 0 to 100 microM. The antioxidant enzymes, viz., peroxidase (POX, E.C.1.11.1.7), catalase (CAT, E.C.1.11.1.6) and superoxide dismutase (SOD, E.C.1.15.1.1) showed significant variation with the increase in lipid peroxidation. |
-induced growth 1(0,0,0,1) | Details |
15908724 | Tsiskarishvili N: [Cuprum vitiligo in children] . Georgian Med News. 2005 Apr;(121):48-51. The effect of this preparation is based on melon's extract rich in antioxidants (catalases and superoxide dismutase). |
and vitix in the treatment of 1(0,0,0,1) | Details |
19618744 | Stolyar OB, Myhayliv RL, Mischuk OV: The concentration-specific response of metallothioneins in -loading freshwater bivalve Anodonta cygnea. Ukr Biokhim Zh. 2005;77(6):68-72. It was accompanied with Cu,Zn-superoxide dismutase (SOD) activation. |
1(0,0,0,1) | Details |
16364055 | Murakami K, Ohara Y, Haneda M, Tsubouchi R, Yoshino M: Prooxidant action of hinokitiol: hinokitiol-iron dependent generation of reactive The inactivation of aconitase was iron-dependent, and prevented by TEMPOL, a scavenger of reactive species and superoxide dismutase, suggesting that the hinokitiol/iron-mediated generation of is responsible for the inactivation of aconitase. |
species. Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):392-4.1(0,0,0,1) | Details |
17701079 | Sharma MC, Joshi C, Das G: Therapeutic management of copper deficiency in buffalo heifers: impact on immune function. Vet Res Commun. 2008 Jan;32(1):49-63. Epub 2007 Aug 14. Similarly, significant improvement in superoxide dismutase activity in red blood cells was observed at the 30th day, and in total leukocytes and whole blood at the 60th day in group A animals. |
1(0,0,0,1) | Details |
19685012 | Arredondo M, Nunez H, Lopez G, Pizarro F, Ayala M, Araya M: Influence of Estrogens on Indicators: In Vivo and In Vitro Studies. Biol Trace Elem Res. 2009 Aug 14. Participants received 8 mg Cu/day (as copper sulfate) during 6 months. Serum Cp and Cu, Cu-Zn-superoxide dismutase activity, liver function indicators [aspartate aminotransferase (AST), alanine aminotransferase (ALT), and gamma glutamyltransferase (GGT)], and serum Fe and Zn concentrations were measured monthly. |
1(0,0,0,1) | Details |
11166292 | Nelli S, McIntosh L, Martin W: Role of cytochrome P450 in the vasodilator actions of the anion generator, Angeli's salt, on rat aorta. Eur J Pharmacol. 2001 Feb 2;412(3):281-9. sulphate enhanced relaxation to Angeli's salt and SNAP but this resulted from reduced destruction of by rather than from enhanced generation of since it was mimicked by superoxide dismutase and by the superoxide dismutase mimetic, MnCl2. |
ions and 1(0,0,0,1) | Details |
15924928 | Sharma MC, Joshi C, Pathak NN, Kaur H: function in heifers. Res Vet Sci. 2005 Oct;79(2):113-23. Epub 2005 Mar 4. Similarly significant improvement in superoxide dismutase activity in RBC was observed at the 30th day, and WBC and whole blood at 60th day in group A animals. |
status and enzyme, hormone, vitamin and immune 1(0,0,0,1) | Details |
17728190 | Garcia Sampaio F, de Lima Boijink C, Tie Oba E, Romagueira Bichara dos Santos L, Lucia Kalinin A, Tadeu Rantin F: Antioxidant defenses and biochemical changes in pacu (Piaractus mesopotamicus) in response to single and combined hypoxia exposure. Comp Biochem Physiol C Toxicol Pharmacol. 2008 Jan;147(1):43-51. Epub 2007 Aug 1. The exposure to 0.4Cu increased the reactive species (ROS) in the liver, accompanied by increases in superoxide dismutase (SOD) and decreases in catalase (CAT) activity, showing the influence of in this protection. |
and 1(0,0,0,1) | Details |
10629812 | Rabiansky PA, McDowell LR, Velasquez-Pereira J, Wilkinson NS, Percival SS, Martin FG, Bates DB, Johnson AB, Batra TR, Salgado-Madriz E: Evaluating copper sulfate sources for heifers. J Dairy Sci. 1999 Dec;82(12):2642-50. In addition to performance, concentrations of Cu, Fe, and Zn in the plasma and liver, plasma ceruloplasmin, hemoglobin, superoxide dismutase (SOD) activity of neutrophils and lymphocytes, and a cell mediated immune response (phytohemagglutinin-P, PHA) were measured. |
and 1(0,0,0,1) | Details |
16799863 | Murakami K, Ishida K, Watakabe K, Tsubouchi R, Haneda M, Yoshino M: Prooxidant action of maltol: role of transition metals in the generation of reactive oxygen species and enhanced formation of 8-hydroxy-2'-deoxyguanosine formation in DNA. Biometals. 2006 Jun;19(3):253-7. Oxidation of by CuSO (4) was effectively stimulated by addition of maltol, and the enhanced oxidation rate was markedly inhibited by the addition of catalase and superoxide dismutase. |
1(0,0,0,1) | Details |
3528599 | Sugiyama E, Iwata M, Yamashita N, Yoshikawa T, Maruyama M, Yano S: Immunosuppression by captopril in vitro: inhibition of human natural killer activity by -dependent generation of peroxide. Jpn J Med. 1986 May;25(2):149-54. However, in the presence of copper sulfate, captopril inhibited the NK activity in a dose-response fashion. |
0(0,0,0,0) | Details |
1512757 | Eguchi K, Kawakami A, Ida H, Nakashima M, Yamashita I, Sakai M, Shimada H, Terada K, Fukuda T, Ishimaru T, et al.: Bucillamine inhibits T cell adhesion to human endothelial cells. . J Rheumatol. 1992 Jul;19(7):1045-50. Addition of copper sulfate to bucillamine decreased significantly the percent T cell adhesion to the EC compared with bucillamine alone. |
0(0,0,0,0) | Details |
7721909 | Eldad A, Wisoki M, Cohen H, Breiterman S, Chaouat M, Wexler MR, Ben-Bassat H: Our previous studies demonstrated deleterious effects of copper sulfate. |
burns: evaluation of various modalities for primary treatment. J Burn Care Rehabil. 1995 Jan-Feb;16(1):49-55.0(0,0,0,0) | Details |
8223958 | Torii Y, Mutoh M, Saito H, Matsuki N: Involvement of free radicals in cisplatin-induced emesis in Suncus murinus. Eur J Pharmacol. 1993 Aug 2;248(2):131-5. However, MPG did not block the emesis induced by copper sulfate (40 mg/kg, p.o.), veratrine (0.5 mg/kg, s.c.) or (10 mg/kg, i.p.). |
0(0,0,0,0) | Details |
3261590 | Matsubara T, Hirohata K: Suppression of human fibroblast proliferation by D-penicillamine and copper sulfate in vitro. Arthritis Rheum. 1988 Aug;31(8):964-72. |
0(0,0,0,0) | Details |
9166989 | Napoli C, Triggiani M, Palumbo G, Condorelli M, Chiariello M, Ambrosio G: Glycosylation enhances radical-induced modifications and decreases acetylhydrolase activity of human low density lipoprotein. Basic Res Cardiol. 1997 Apr;92(2):96-105. Parallel experiments were done in the presence of the scavenger superoxide dismutase (SOD; 330 U/ml), the peroxide scavenger catalase (1000 U/ml), or the scavenger dimethylthiourea (10 mM) or dimethylsulfoxide (1 mM). |
1(0,0,0,1) | Details |
19665240 | Wu TM, Hsu YT, Sung MS, Hsu YT, Lee TM: Expression of genes involved in redox homeostasis and antioxidant defense in a marine macroalga Ulva fasciata by excess Phycologia 47, 346-360] were cloned and their expression was compared to superoxide dismutase (UfMnsod and UfFesod), peroxidase (UfApx), glutathione reductase (UfGr), and catalase (UfCat). |
Aquat Toxicol. 2009 Oct 4;94(4):275-85. Epub 2009 Jul 19.1(0,0,0,1) | Details |
15836927 | Qian Y, Zheng Y, Abraham L, Ramos KS, Tiffany-Castiglioni E: Differential profiles of neuroblastoma and astrocytoma cells. Brain Res Mol Brain Res. 2005 Apr 4;134(2):323-32. Epub 2005 Jan 13. Differences in Cu-induced ROS between two cell lines paralleled superoxide dismutase (SOD)-catalase expression as detected by Western blot analysis. |
-induced ROS generation in human 1(0,0,0,1) | Details |
11003114 | Zhang SS, Noordin MM, Rahman SO, Haron J: Effects of Malondialdehyde (MDA), Cu-Zn superoxide dismutase (SOD), and Se- peroxidase (GSH-Px) were measured in serum and liver homogenate at 2, 4 and 8 w of dosing. |
overload on hepatic lipid peroxidation and antioxidant defense in rats. Vet Hum Toxicol. 2000 Oct;42(5):261-4.1(0,0,0,1) | Details |
9093389 | Kimura T, Nishioka H: Intracellular generation of E. coli strain lacking either superoxide dismutases or oxidative DNA repair enzymes was hypersensitive to killing by CuSO4. |
by sulphate in Escherichia coli. Mutat Res. 1997 Mar 17;389(2-3):237-42.1(0,0,0,1) | Details |
14962827 | Mao W, Qin F, Iwai C, Vulapalli R, Keng PC, Liang CS: Extracellular reduces neuronal uptake of by oxidative stress in PC12 cells. Am J Physiol Heart Circ Physiol. 2004 Jul;287(1):H29-39. Epub 2004 Feb 12. In addition, the free-radical scavenger and antioxidant enzymes superoxide dismutase and catalase, reduced oxidative stress and attenuated the reductions of NE uptake activity and NET protein produced by NE/Cu. |
1(0,0,0,1) | Details |
6284041 | Russanov EM, Ljutakova SG, Leutchev SI: Effect of CuSO4 and Cu (II)(Gly) 2 on some indirect assays for superoxide dismutase activity. Arch Biochem Biophys. 1982 Apr 15;215(1):222-9. |
1(0,0,0,1) | Details |
17916969 | Feng J, Ma WQ, Gu ZL, Wang YZ, Liu JX: Effects of dietary 160 crossbred (Duroc x Landrace x Yorkshire) gilts averaged 21.25 kg body weight were used to study the effects of dietary (II) (CuSO4) and proteinate (Cu-Pr) on growth performance, plasma Cu concentration, ceruloplasmin activity, and erythrocyte Cu/Zn-superoxide dismutase (SOD) activity. |
(II) and proteinate on performance and blood indexes of status in growing pigs. Biol Trace Elem Res. 2007 Winter;120(1-3):171-8.1(0,0,0,1) | Details |
12722182 | Hernandez-Saavedra NY: Cu,Zn superoxide dismutase in Rhodotorula and Udeniomyces spp. isolated from sea water: cloning and sequencing the encoding region. Yeast. 2003 Apr 30;20(6):479-92. |
1(0,0,0,1) | Details |
10816044 | Fernandes AR, Prieto M, Sa-Correia I: Modification of plasma membrane lipid order and H+-ATPase activity as part of the response of Saccharomyces cerevisiae to cultivation under mild and high stress. Arch Microbiol. 2000 Apr;173(4):262-8. The adaptive mechanisms examined in this study included the coordinate increase in the activities of Cu,Zn-superoxide dismutase (up to five-fold), glutathione reductase (up to 1.7-fold), and plasma membrane H+-ATPase (up to three-fold). |
1(0,0,0,1) | Details |
9172377 | Matsuo T, Ooe S, Ishikawa Y: Limitation of dietary superoxide dismutase activity in the onion fly, Delia antiqua. Comp Biochem Physiol A Physiol. 1997 Jun;117(2):191-5. |
and zinc decreases 1(0,0,0,1) | Details |
20213433 | Sampaio FG, de Lima Boijink C, Dos Santos LR, Oba ET, Kalinin AL, Rantin FT: The combined effect of Copper sulfate is widely used in aquaculture. In liver and red muscle, the superoxide dismutase (SOD) was responsive to the increases in the aquatic |
and low pH on antioxidant defenses and biochemical parameters in neotropical fish pacu, Piaractus mesopotamicus (Holmberg, 1887). Ecotoxicology. 2010 Mar 6.1(0,0,0,1) | Details |
11299314 | Paris I, Dagnino-Subiabre A, Marcelain K, Bennett LB, Caviedes P, Caviedes R, Azar CO, Segura-Aguilar J: mediated uptake and one-electron reduction of aminochrome in a rat substantia nigra neuronal cell line. J Neurochem. 2001 Apr;77(2):519-29. Copper sulfate (1 m M) alone was not toxic to RCSN-3 cells, but was when combined with or with dicoumarol (95% toxicity; p < 0.001) which inhibits and TPNH (DT)-diaphorase. A decrease in the expression of CuZn-superoxide dismutase and peroxidase mRNA was observed when RCSN-3 cells were treated with CuSO (4), or CuSO (4) and |
neurotoxicity is dependent on -1(0,0,0,1) | Details |
12782727 | Shikanai T, Muller-Moule P, Munekage Y, Niyogi KK, Pilon M: PAA1, a P-type ATPase of Arabidopsis, functions in transport in chloroplasts. Plant Cell. 2003 Jun;15(6):1333-46. Cu transport into chloroplasts provides the cofactor for the stromal enzyme /zinc superoxide dismutase (Cu/ZnSOD) and for the thylakoid lumen protein plastocyanin, which functions in photosynthetic electron transport from the cytochrome b (6) f complex to photosystem I. |
1(0,0,0,1) | Details |
16261369 | Fujimori T, Yamada S, Yasui H, Sakurai H, In Y, Ishida T: Orally active antioxidative synthesis, structure characterization, scavenging activity, and in vitro and in vivo antioxidative evaluations. J Biol Inorg Chem. 2005 Dec;10(8):831-41. Epub 2005 Oct 28. Ever since it was proposed that reactive species (ROS) are involved in the pathogeneses of various diseases, superoxide dismutase (SOD)-mimetic complexes have been intensively studied. |
(II) aspirinate: 1(0,0,0,1) | Details |