| Name | cholinesterases |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | oxydemeton-methyl |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9891917 | Astroff AB, Young AD: The relationship between maternal and fetal effects following maternal organophosphate exposure during gestation in the rat. Toxicol Ind Health. 1998 Nov-Dec;14(6):869-89. This study compared the maternal and fetal effects, including cholinesterase inhibition, following gestational exposure to six organophosphates: tribufos, oxydemeton-methyl, azinphos-methyl, fenamiphos, isofenphos, and fenthion in the Sprague-Dawley rat. |
86(1,1,1,6) | Details |
| 10794385 | Sheets LP: A consideration of age-dependent differences in susceptibility to organophosphorus and pyrethroid insecticides. Neurotoxicology. 2000 Feb-Apr;21(1-2):57-63. The first involves multi-generation reproduction studies with rats that were treated with OP insecticides (coumaphos, fenamiphos, tribufos, trichlorfon, or oxydemeton-methyl) through the diet and examined for effects, including cholinesterase (ChE) inhibition. |
31(0,1,1,1) | Details |
| 11993279 | Pogacnik L, Franko M: Validation of different commercially available cholinesterases for pesticide toxicity test. Ann Chim. 2002 Jan-Feb;92(1-2):93-101. A systematic study of different commercially available cholinesterases (AChEs from electric eel, human erythrocytes, bovine erythrocytes and BuChE from horse serum) for the FIA determination of some frequently used organophosphate (paraoxon, oxydemeton-methyl, triazophos, diazionon) and (carbofuran, propoxur) pesticides was carried out. |
10(0,0,1,5) | Details |
| 2729280 | Ames RG, Brown SK, Mengle DC, Kahn E, Stratton JW, Jackson RJ: Cholinesterase activity depression among California agricultural pesticide applicators. Am J Ind Med. 1989;15(2):143-50. Pesticides most frequently associated with cholinesterase depressions exceeding California threshold values included mevinphos (Phosdrin), oxydemeton methyl (Metasystox-R), methomyl (Lannate), and acephate (Orthene); these pesticides included organophosphates in toxicity categories I and II and one in toxicity category I. |
9(0,0,1,4) | Details |
| 18968286 | Pogacnik L, Franko M: Optimisation of FIA system for detection of organophosphorus and pesticides based on cholinesterase inhibition. Talanta. 2001 May 30;54(4):631-41. Responses to some frequently used organophosphorus (paraoxon, oxydemeton-methyl, triazophos) and (carbofuran, propoxur) pesticides were found to be dependent on the origin of cholinesterases. |
9(0,0,1,4) | Details |
| 9875697 | Astroff AB, Freshwater KJ, Eigenberg DA: Comparative organophosphate-induced effects observed in adult and neonatal Sprague-Dawley rats during the conduct of multigeneration toxicity studies. Reprod Toxicol. 1998 Nov-Dec;12(6):619-45. Five organophosphates: tribufos, oxydemeton-methyl, fenamiphos, coumaphos, and trichlorfon were evaluated for their potential to produce reproductive and neonatal toxicity following continuous dietary exposure during multigenerational reproduction toxicity studies in the Sprague-Dawley rat. Significant inhibition of parental cholinesterase activities (plasma, erythrocyte, and brain) was similarly observed in both generations with all test compounds, with at least the highest concentrations. |
3(0,0,0,3) | Details |
| 8714219 | Cochran RC, Formoli TA, Silva MH, Kellner TP, Lewis CM, Pfeifer KF: Risks from occupational and dietary exposure to mevinphos. Rev Environ Contam Toxicol. 1996;146:1-24. The principal toxic effects of mevinphos, both short- and long term, were due to inhibition of cholinesterase activity. Because no acceptable exposure studies for work tasks associated with ground application of mevinphos were available, surrogate data based on ground application of oxydemeton-methyl were used. |
1(0,0,0,1) | Details |
| 19778163 | Eyer F, Worek F, Eyer P, Felgenhauer N, Haberkorn M, Zilker T, Thiermann H: Obidoxime in acute organophosphate poisoning: 1 - clinical effectiveness. Clin Toxicol. 2009 Sep;47(8):798-806. In this article we report clinical findings and activity of cholinesterase in plasma and acetylcholinesterase (AChE) in red blood cells. METHODS: We studied 34 atropinized patients with severe parathion, oxydemeton methyl, and dimethoate self-poisoning who were treated with obidoxime in a standard protocol. |
1(0,0,0,1) | Details |
| 10207609 | Worek F, Diepold C, Eyer P: Dimethylphosphoryl-inhibited human cholinesterases: inhibition, reactivation, and aging kinetics. Arch Toxicol. 1999 Feb;73(1):7-14. Human poisoning by organophosphates bearing two methoxy groups, e.g. by malathion, paraoxon-methyl, dimethoate and oxydemeton-methyl, is generally considered to be rather resistant to oxime therapy. |
1(0,0,0,1) | Details |
| 18281183 | Schrickel JW, Lewalter T, Luderitz B, Nickenig G, Klehr HU, Rabe C: Recovery from ultra-high dose organophosphate poisoning after "in-the-field" antidote treatment: potential lessons for civil defense. J Emerg Med. 2009 Oct;37(3):279-82. Epub 2008 Feb 20. Two patients orally ingested large amounts of the organophosphorous agent oxydemeton-methyl in suicide attempts, resulting in the hypercholinergic syndrome in both. Plasma levels of pseudo cholinesterase were initially very low in both patients. |
1(0,0,0,1) | Details |