Protein Information

Name IL 10
Synonyms B TCGF; B cell derived T cell growth factor; CSIF; Cytokine synthesis inhibitory factor; IL 10; IL10; IL10A; Interleukin 10…

Compound Information

Name paraquat
CAS 1,1′-dimethyl-4,4′-bipyridinium

Reference List

PubMed Abstract RScore(About this table)
18441283 Cho YS, Oh SY, Zhu Z: Tyrosine phosphatase SHP-1 in oxidative stress and development of allergic airway inflammation. Am J Respir Cell Mol Biol. 2008 Oct;39(4):412-9. Epub 2008 Apr 25.

This includes a significant enhancement of intracellular reactive oxygen species and STAT6 phosphorylation in vitro and increased CCL20, decreased IL-10, and increased number of dendritic cells in BAL fluid in vivo.
Hydrogen peroxide (H (2) O (2)) and Paraquat were used in vitro and in vivo, respectively.
1(0,0,0,1) Details
17535659 Jian XD, Sui H, Chu ZH, Zhang ZW, Kan BT, Zhang L, Zhang HT: [Changes of serum cytokine caused by acute paraquat poisoning] . Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2007 Apr;25(4):230-2.

OBJECTIVE: To observe the change of cytokine interleukin IL-1 beta, IL-6, IL-10, tumor necrosis factor-alpha (TNF-alpha) occurred in acute paraquat (PQ) poisoning rats and to investigate the mechanism of acute lung injury caused by paraquat (PQ) poisoning.
32(0,1,1,2) Details
19567158 Shang Y, Xu SP, Wu Y, Jiang YX, Wu ZY, Yuan SY, Yao SL: Melatonin reduces acute lung injury in endotoxemic rats. Chin Med J. 2009 Jun 20;122(12):1388-93.

BACKGROUND: Treatment with melatonin significantly reduces lung injury induced by bleomycin, paraquat and ischemia reperfusion.
Wet/dry ratios (W/D), myeloperoxidase activity, malondialdehyde concentrations and tumor necrosis factor-alpha (TNF-alpha) and interleukin-10 (IL-10) levels in lungs were measured.
2(0,0,0,2) Details
19497220 He XY, Sun Q, Li ZW, Lu ZQ, Hong GL, Liang H, Qiu QM, Hu GX: [Expression of inflammatory factors in lung tissue of acute paraquat poisoned rats]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2009 Mar;27(3):149-52.

The level of tumor necrosis factor alpha (TNF-alpha) mRNA, interleukin 10 (IL-10) mRNA, high mobility group box 1 (HMGB-1) mRNA in lung of rats were detected.
3(0,0,0,3) Details